Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 162146980

GI number: 162146980

Start: 1180756

End: 1182150

Strand: Reverse

Name: pabB [H]

Synonym: GDI_1185

Alternate gene names: 162146980

Gene position: 1182150-1180756 (Counterclockwise)

Preceding gene: 162146981

Following gene: 162146979

Centisome position: 29.97

GC content: 74.12

Gene sequence:

>1395_bases
ATGGATGGTCCGGTTGGCATCGGGGACCTTCACGCCGTCGAACTGCCGTGGCGGGACCCTGATGACGTGCTGTGGGCGTG
GCGGGACGAACCGTGGCTGGCCTGCCTGGACAGCGGCGGGCCGGCGGGGCCGCGCGCGCGCTGGACCATCCTCTGCCGCC
GGCCGCGCCAGGTCCTTGAATGGCGGGACGGCGGGGCCCCGCTGGCATCTGATCCGCTGGCGGCCCTGCGCGCCCTGCTG
CCGCCGGCCGGATCGCCGCCCGTGACCGCATCCGGCGAGGCCCTGCCGTTCGCGGGCGGGGTGATCGGCTTCGCCGGGTA
CGGGGTGGGGCGGCGCCTCGAAGGGATCGCGACCCGCCACGTGGCCGATCCGGCCCAGCCGGACCTGGCGGCGGGGTTCT
ATGACCATGCCGTCCTGTTCGACCGTGTGCGGCGGCGCGCCTACCTGGCGACGATCCGCCCCGATCCGGACCGGCTGATC
GCCGACGTAAGCGCCGCGTGGGCGGCCATGGAGCCGGCCCCGGCCCCCGCCGCCCTGCCGCGCCTGGCCTTCGCCGCCGA
CCAGGCGCCGGGGCAGTACGCCGCCGCGGTGGCGCGCGCGGTGGAGCGGATCGCGGCGGGCGACATCTTCCAGGTCAACA
TCACCGGGCGCATGGCCGCCCGCCGCCCGCCCGGCCTGACGGACGGCGCCATCTACCGGGCCCTGCGCCGGGCCTCGCCC
GCGCCGTTCGGGGCGTGGCTGGCCTGCGGGCCGGGTTTCGGCCTGCTGTCGGCCTCGCCGGAGCGGTTCGTGCATCTCGG
CCCTGACGGGGTGGCCCGCACCCGGCCGATCAAGGGCACCCGCCCGCGCGGCGCCACCCCGGCACAGGATGCCGCCCGCC
GTGTCGAACTCGCGGCCGATGAGAAGGAACGGGCGGAAAACCTGATGATCGTGGACCTGATGCGCAACGATCTGGGTCGT
GTCGCGCGGATCGGCAGCGTCGGTGTCCCGGAACTGCTGTCGGTGGAGACCTTCACCCATGTCCATCACCTGGTGTCCGA
GGTCACGGCCACCCTGGCCCCGGGACGGGATGCCATCGACCTGCTGCGCGCCACCCTGCCGCCCGGATCGGTGACCGGCG
CGCCGAAGCACCGCGCGATGCAGATCATCGACGAACTGGAATCGTCGGCGCGGCAGGCCTATTGCGGGGTGGTCTTTCGC
ATCGGCACCGATGGCGCGATGGACAGTTCGGTCGTCATCCGCGCCCTGGCCACGACGCCGGATGCGATCGTGGCGGCGGC
GGGGGGCGGGATCACGATCCTGTCGGACCCCGGGCGGGAATATGCGGAAATGTGCCTGAAGATCGCGCCGCTGCTGGCCC
TGTTCGGGGCCGAGCCGGCCGGGATGGCGTCATGA

Upstream 100 bases:

>100_bases
TCGAGGACTGCCGACGGCTGGCCCACCGCGTGATGGAATCCCCGGACGTGGCCGAAGTCCTGTCCCTGATCGACGCCTTC
GCCGCGGGGGGGTAGCGGTC

Downstream 100 bases:

>100_bases
CGATGCTGTGGCTGAATGACGGGCTGGTCCCGGCGGACCGGGCGCGGATCGATCCCGCCGATCGCGGCCTGACCCTGGGT
GACGGACTGTTCGAGACGAT

Product: Para-aminobenzoate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MDGPVGIGDLHAVELPWRDPDDVLWAWRDEPWLACLDSGGPAGPRARWTILCRRPRQVLEWRDGGAPLASDPLAALRALL
PPAGSPPVTASGEALPFAGGVIGFAGYGVGRRLEGIATRHVADPAQPDLAAGFYDHAVLFDRVRRRAYLATIRPDPDRLI
ADVSAAWAAMEPAPAPAALPRLAFAADQAPGQYAAAVARAVERIAAGDIFQVNITGRMAARRPPGLTDGAIYRALRRASP
APFGAWLACGPGFGLLSASPERFVHLGPDGVARTRPIKGTRPRGATPAQDAARRVELAADEKERAENLMIVDLMRNDLGR
VARIGSVGVPELLSVETFTHVHHLVSEVTATLAPGRDAIDLLRATLPPGSVTGAPKHRAMQIIDELESSARQAYCGVVFR
IGTDGAMDSSVVIRALATTPDAIVAAAGGGITILSDPGREYAEMCLKIAPLLALFGAEPAGMAS

Sequences:

>Translated_464_residues
MDGPVGIGDLHAVELPWRDPDDVLWAWRDEPWLACLDSGGPAGPRARWTILCRRPRQVLEWRDGGAPLASDPLAALRALL
PPAGSPPVTASGEALPFAGGVIGFAGYGVGRRLEGIATRHVADPAQPDLAAGFYDHAVLFDRVRRRAYLATIRPDPDRLI
ADVSAAWAAMEPAPAPAALPRLAFAADQAPGQYAAAVARAVERIAAGDIFQVNITGRMAARRPPGLTDGAIYRALRRASP
APFGAWLACGPGFGLLSASPERFVHLGPDGVARTRPIKGTRPRGATPAQDAARRVELAADEKERAENLMIVDLMRNDLGR
VARIGSVGVPELLSVETFTHVHHLVSEVTATLAPGRDAIDLLRATLPPGSVTGAPKHRAMQIIDELESSARQAYCGVVFR
IGTDGAMDSSVVIRALATTPDAIVAAAGGGITILSDPGREYAEMCLKIAPLLALFGAEPAGMAS
>Mature_464_residues
MDGPVGIGDLHAVELPWRDPDDVLWAWRDEPWLACLDSGGPAGPRARWTILCRRPRQVLEWRDGGAPLASDPLAALRALL
PPAGSPPVTASGEALPFAGGVIGFAGYGVGRRLEGIATRHVADPAQPDLAAGFYDHAVLFDRVRRRAYLATIRPDPDRLI
ADVSAAWAAMEPAPAPAALPRLAFAADQAPGQYAAAVARAVERIAAGDIFQVNITGRMAARRPPGLTDGAIYRALRRASP
APFGAWLACGPGFGLLSASPERFVHLGPDGVARTRPIKGTRPRGATPAQDAARRVELAADEKERAENLMIVDLMRNDLGR
VARIGSVGVPELLSVETFTHVHHLVSEVTATLAPGRDAIDLLRATLPPGSVTGAPKHRAMQIIDELESSARQAYCGVVFR
IGTDGAMDSSVVIRALATTPDAIVAAAGGGITILSDPGREYAEMCLKIAPLLALFGAEPAGMAS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=434, Percent_Identity=39.4009216589862, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1787518, Length=301, Percent_Identity=33.8870431893688, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1786809, Length=266, Percent_Identity=25.187969924812, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=441, Percent_Identity=31.7460317460317, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6324361, Length=397, Percent_Identity=27.7078085642317, Blast_Score=139, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 48830; Mature: 48830

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGPVGIGDLHAVELPWRDPDDVLWAWRDEPWLACLDSGGPAGPRARWTILCRRPRQVLE
CCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEEEECCCHHHHH
WRDGGAPLASDPLAALRALLPPAGSPPVTASGEALPFAGGVIGFAGYGVGRRLEGIATRH
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
VADPAQPDLAAGFYDHAVLFDRVRRRAYLATIRPDPDRLIADVSAAWAAMEPAPAPAALP
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHH
RLAFAADQAPGQYAAAVARAVERIAAGDIFQVNITGRMAARRPPGLTDGAIYRALRRASP
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHCCC
APFGAWLACGPGFGLLSASPERFVHLGPDGVARTRPIKGTRPRGATPAQDAARRVELAAD
CCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
EKERAENLMIVDLMRNDLGRVARIGSVGVPELLSVETFTHVHHLVSEVTATLAPGRDAID
HHHHHCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LLRATLPPGSVTGAPKHRAMQIIDELESSARQAYCGVVFRIGTDGAMDSSVVIRALATTP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHCCC
DAIVAAAGGGITILSDPGREYAEMCLKIAPLLALFGAEPAGMAS
CCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDGPVGIGDLHAVELPWRDPDDVLWAWRDEPWLACLDSGGPAGPRARWTILCRRPRQVLE
CCCCCCCCCCEEEECCCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEEEECCCHHHHH
WRDGGAPLASDPLAALRALLPPAGSPPVTASGEALPFAGGVIGFAGYGVGRRLEGIATRH
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
VADPAQPDLAAGFYDHAVLFDRVRRRAYLATIRPDPDRLIADVSAAWAAMEPAPAPAALP
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHH
RLAFAADQAPGQYAAAVARAVERIAAGDIFQVNITGRMAARRPPGLTDGAIYRALRRASP
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHCCC
APFGAWLACGPGFGLLSASPERFVHLGPDGVARTRPIKGTRPRGATPAQDAARRVELAAD
CCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
EKERAENLMIVDLMRNDLGRVARIGSVGVPELLSVETFTHVHHLVSEVTATLAPGRDAID
HHHHHCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LLRATLPPGSVTGAPKHRAMQIIDELESSARQAYCGVVFRIGTDGAMDSSVVIRALATTP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHCCC
DAIVAAAGGGITILSDPGREYAEMCLKIAPLLALFGAEPAGMAS
CCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]