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The map label for this gene is emrK [H]

Identifier: 162146816

GI number: 162146816

Start: 1013728

End: 1014804

Strand: Reverse

Name: emrK [H]

Synonym: GDI_0998

Alternate gene names: 162146816

Gene position: 1014804-1013728 (Counterclockwise)

Preceding gene: 162146817

Following gene: 162146815

Centisome position: 25.73

GC content: 68.8

Gene sequence:

>1077_bases
ATGAACGGAACAACGAAGGCGCTGCTGCTGGCGGCCGGCGTGGTGGTGCTGGGGGCCGCGGCCTGGGGCGGTGACCGCCT
TGTGCTTGGAGACGGCGTGCGGGTCGAGACCAACGACGCCTATGTGTCTGCCTATTCCTCGGTGGTCGCCCCCAAGGTCG
GCGGTCGCATCGACGCCGTGATGGCGCAAGACAACGAGCAGGTCCGCAAAGGCGAGGTGCTGGCCCATATCGAGGATGAC
GACTACCGCGCAGCTCTTACCGTGGCGCGGGGCAATCTCGCCGCCGCGCGCGCCGACATCGCCAATCTGCAGGCGGAGTT
GGCCCGGCAGGATGCGCTGATCGCGGCGGCACGGGCGGCGGTACAATCTGACGACGCTGAACTCGTCTTCGCGCAGCAGG
ACGAGGCGCGCTACCGCAATCTGGCGGTCGGTGGCGCCGGCACGACCGAGCAGCGCCAGCGTACGGCGGCGCAGACCCGC
GAGGCCACGGCCGCGAAAGCCCGCGACGAGGCGAGTGTGCAGGCCGCGACCCAGGAAAAGGATGTGCTCGCCGCCCAGAT
CGCGCGTGCCAGGGGCAACCTGACCCGCGCCGAAGGCGAGGAGCAGCGGGCAGAATTGGATTTGTCCTATTGCACCATCC
CGGCCCCGGTGGACGGCGTGGTCGGCGCGCGCGGCGTGCGTGTGGGCAACTACGTTAATCCCGGCAGTGCGCTGATGGCG
GTCACCCCGGTCCAGGATGCGTTCGTGGTTGCCCATTTCCAGGAGACGCAACTCACGCATGTTGTGCCGGGGCAGAAAGC
GACGGTCTGGGTCGACACCTTCCCGGGTCAGCCACTGCGCGCTCATGTCGACAGCATCCCGCCGGCGACCGGCGTCGCGT
TCGCGCCGATCCAGCCCGATAATGCGACCGGCAACTTCACCAAGGTGGTCCAGCGTCTGCCGGTGCGCATCACCTTCGAT
CCGGGGCAGCCACTTGCCGCGCGCGTCAGGGTCGGCATGTCGGTGGAAGTCAGGGTCGACACGGCCTCCCGTCCCGAAGG
CCCGAAGGCGGACGACCCCCGCTATGCTTGGCGGTGA

Upstream 100 bases:

>100_bases
TCGTGGCCCTCGTCGTAACGATCTACCTGAAGCTGACCTGACGGTCCCGCGCAATCCGCGACAGACGATGTGGCCGCCGG
GGCCGCAAGAGGGAATATTC

Downstream 100 bases:

>100_bases
GGGGCGGATCATGATCACACGCCTCAACCGCCCCATGCTCGCTCTGGCGAGCGCGCTCCTGCTCGGCGCCTGCACGGTCG
GGCCCGACTATCACAAGCCG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNGTTKALLLAAGVVVLGAAAWGGDRLVLGDGVRVETNDAYVSAYSSVVAPKVGGRIDAVMAQDNEQVRKGEVLAHIEDD
DYRAALTVARGNLAAARADIANLQAELARQDALIAAARAAVQSDDAELVFAQQDEARYRNLAVGGAGTTEQRQRTAAQTR
EATAAKARDEASVQAATQEKDVLAAQIARARGNLTRAEGEEQRAELDLSYCTIPAPVDGVVGARGVRVGNYVNPGSALMA
VTPVQDAFVVAHFQETQLTHVVPGQKATVWVDTFPGQPLRAHVDSIPPATGVAFAPIQPDNATGNFTKVVQRLPVRITFD
PGQPLAARVRVGMSVEVRVDTASRPEGPKADDPRYAWR

Sequences:

>Translated_358_residues
MNGTTKALLLAAGVVVLGAAAWGGDRLVLGDGVRVETNDAYVSAYSSVVAPKVGGRIDAVMAQDNEQVRKGEVLAHIEDD
DYRAALTVARGNLAAARADIANLQAELARQDALIAAARAAVQSDDAELVFAQQDEARYRNLAVGGAGTTEQRQRTAAQTR
EATAAKARDEASVQAATQEKDVLAAQIARARGNLTRAEGEEQRAELDLSYCTIPAPVDGVVGARGVRVGNYVNPGSALMA
VTPVQDAFVVAHFQETQLTHVVPGQKATVWVDTFPGQPLRAHVDSIPPATGVAFAPIQPDNATGNFTKVVQRLPVRITFD
PGQPLAARVRVGMSVEVRVDTASRPEGPKADDPRYAWR
>Mature_358_residues
MNGTTKALLLAAGVVVLGAAAWGGDRLVLGDGVRVETNDAYVSAYSSVVAPKVGGRIDAVMAQDNEQVRKGEVLAHIEDD
DYRAALTVARGNLAAARADIANLQAELARQDALIAAARAAVQSDDAELVFAQQDEARYRNLAVGGAGTTEQRQRTAAQTR
EATAAKARDEASVQAATQEKDVLAAQIARARGNLTRAEGEEQRAELDLSYCTIPAPVDGVVGARGVRVGNYVNPGSALMA
VTPVQDAFVVAHFQETQLTHVVPGQKATVWVDTFPGQPLRAHVDSIPPATGVAFAPIQPDNATGNFTKVVQRLPVRITFD
PGQPLAARVRVGMSVEVRVDTASRPEGPKADDPRYAWR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=335, Percent_Identity=30.7462686567164, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789041, Length=312, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790519, Length=301, Percent_Identity=28.9036544850498, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789637, Length=294, Percent_Identity=27.891156462585, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790024, Length=280, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790012, Length=277, Percent_Identity=25.2707581227437, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37857; Mature: 37857

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTTKALLLAAGVVVLGAAAWGGDRLVLGDGVRVETNDAYVSAYSSVVAPKVGGRIDAV
CCCHHHHHHHHHHHHHEEEECCCCCEEEEECCEEEECCCHHHHHHHHHHCCCCCCCEEEE
MAQDNEQVRKGEVLAHIEDDDYRAALTVARGNLAAARADIANLQAELARQDALIAAARAA
EECCCCHHCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSDDAELVFAQQDEARYRNLAVGGAGTTEQRQRTAAQTREATAAKARDEASVQAATQEK
HCCCCCEEEEECCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DVLAAQIARARGNLTRAEGEEQRAELDLSYCTIPAPVDGVVGARGVRVGNYVNPGSALMA
HHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCCCCCCCCCCCCEEECCEECCCCEEEE
VTPVQDAFVVAHFQETQLTHVVPGQKATVWVDTFPGQPLRAHVDSIPPATGVAFAPIQPD
EECCCCEEEEEEECCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCCCCCCEEEECCCCC
NATGNFTKVVQRLPVRITFDPGQPLAARVRVGMSVEVRVDTASRPEGPKADDPRYAWR
CCCCHHHHHHHHCCEEEEECCCCCHHHHEEECCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGTTKALLLAAGVVVLGAAAWGGDRLVLGDGVRVETNDAYVSAYSSVVAPKVGGRIDAV
CCCHHHHHHHHHHHHHEEEECCCCCEEEEECCEEEECCCHHHHHHHHHHCCCCCCCEEEE
MAQDNEQVRKGEVLAHIEDDDYRAALTVARGNLAAARADIANLQAELARQDALIAAARAA
EECCCCHHCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSDDAELVFAQQDEARYRNLAVGGAGTTEQRQRTAAQTREATAAKARDEASVQAATQEK
HCCCCCEEEEECCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DVLAAQIARARGNLTRAEGEEQRAELDLSYCTIPAPVDGVVGARGVRVGNYVNPGSALMA
HHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCCCCCCCCCCCCEEECCEECCCCEEEE
VTPVQDAFVVAHFQETQLTHVVPGQKATVWVDTFPGQPLRAHVDSIPPATGVAFAPIQPD
EECCCCEEEEEEECCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCCCCCCEEEECCCCC
NATGNFTKVVQRLPVRITFDPGQPLAARVRVGMSVEVRVDTASRPEGPKADDPRYAWR
CCCCHHHHHHHHCCEEEEECCCCCHHHHEEECCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]