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The map label for this gene is engD [H]

Identifier: 162146759

GI number: 162146759

Start: 952002

End: 953096

Strand: Direct

Name: engD [H]

Synonym: GDI_0937

Alternate gene names: 162146759

Gene position: 952002-953096 (Clockwise)

Preceding gene: 162146758

Following gene: 162146761

Centisome position: 24.14

GC content: 67.21

Gene sequence:

>1095_bases
ATGGGGTTCAATTGCGGCATCGTGGGCCTGCCGAATGTCGGCAAGTCCACTCTGTTCAACGCCCTGACCGAAACCGCGTC
GGCCCAGGCCGCGAACTATCCGTTCTGCACGATCGAACCGAATGTCGGCCGCGTGGCGGTGCCCGACCCGCGACTGCAGG
CCCTGGCCGCCATCGGCAAGTCGCAGAAGATCCTGCCGACCAGCCTGGAATTCGTCGATATCGCGGGCCTGGTGCGCGGC
GCCTCGCGCGGCGAGGGACTGGGCAACCAGTTCCTGGCGAATATCCGCGAGGTCGATGCGATCATCCACGTCCTGCGCTG
TTTCGAGGATGACGACATCACCCATGTCGAAGGCGGGATCGATCCGATCCGCGACGCCGAGATCATCGAGACCGAACTGA
TGCTGGCGGACCTGGATTCGCTGGAAAAGCGCATCGTCGCCCTGCAGAAGAAGGCCAAGGGCAACGACCGCGACGCCGCC
GCCCAGGTCGCGCTGATGGAACCGCTGATCGCGGTCCTGCGCGAGGGCCGGCCCGCCCGCCAGGCCATTCCCGCCGGGCA
GGAAGAGGCCGTGCGCCGCCTGCAGCTGATGACCAGCAAGCCGGTCCTGTATGTCTGCAATGTCGAGGAAGCCTCGGCCG
CCACCGGCAATGAATGGTCCGAACGCGTCCGGGCCCGGGCCGAGGCCGAGGGCGCGGTCGCCGTCGTGGTCTCCGCCGCG
ATCGAGGCCGAGGTCAGCCAGCTCGGCCCCGAGGACCGCAAGGAATTCCTCGACGGGCTGGGCCTGTCCGACAGCGGCCT
GGACCGGGTGATCGCCGCGGGCTACCGCCTGCTGGGCCTGCGGACCTATTTCACCGTGGGGCCCAAGGAAACCCGTGCCT
GGACGATCACCGCCGGCACCCGCGCGCCCCAGGCCGCCGCCGTGATCCATAATGATTTCGAACGCGGCTTCATCGCCTGC
GAAACCGTCGCCTATGACGACTACATTCGCTACCAGGGCGAAGCGGGCGCCAAGGAAGCCGGCAAGCTGCGGATCGAAGG
CCGCGACTATGTCGTGCAGGATGGCGACGTCCTCCTCTTCCGCTTCAACGTCTGA

Upstream 100 bases:

>100_bases
GCATGCTCGACGCCATGTCCGACACGGCGCCGGTCCTGGCGGACGGGCAGCCCGAACTGTTCATGACGAAGATGGCCTTG
CTGGCCGGGGAGAAGGGCTG

Downstream 100 bases:

>100_bases
AAAAGGGGCTGGAGACGCGCCCTGTCGGCGATCCGACGCGCGTTTCCTGCGCTCCGGTGCTCACGGCCATCAAGGCCGCT
CTGCTCCGGCGCTCGGAAAC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MGFNCGIVGLPNVGKSTLFNALTETASAQAANYPFCTIEPNVGRVAVPDPRLQALAAIGKSQKILPTSLEFVDIAGLVRG
ASRGEGLGNQFLANIREVDAIIHVLRCFEDDDITHVEGGIDPIRDAEIIETELMLADLDSLEKRIVALQKKAKGNDRDAA
AQVALMEPLIAVLREGRPARQAIPAGQEEAVRRLQLMTSKPVLYVCNVEEASAATGNEWSERVRARAEAEGAVAVVVSAA
IEAEVSQLGPEDRKEFLDGLGLSDSGLDRVIAAGYRLLGLRTYFTVGPKETRAWTITAGTRAPQAAAVIHNDFERGFIAC
ETVAYDDYIRYQGEAGAKEAGKLRIEGRDYVVQDGDVLLFRFNV

Sequences:

>Translated_364_residues
MGFNCGIVGLPNVGKSTLFNALTETASAQAANYPFCTIEPNVGRVAVPDPRLQALAAIGKSQKILPTSLEFVDIAGLVRG
ASRGEGLGNQFLANIREVDAIIHVLRCFEDDDITHVEGGIDPIRDAEIIETELMLADLDSLEKRIVALQKKAKGNDRDAA
AQVALMEPLIAVLREGRPARQAIPAGQEEAVRRLQLMTSKPVLYVCNVEEASAATGNEWSERVRARAEAEGAVAVVVSAA
IEAEVSQLGPEDRKEFLDGLGLSDSGLDRVIAAGYRLLGLRTYFTVGPKETRAWTITAGTRAPQAAAVIHNDFERGFIAC
ETVAYDDYIRYQGEAGAKEAGKLRIEGRDYVVQDGDVLLFRFNV
>Mature_363_residues
GFNCGIVGLPNVGKSTLFNALTETASAQAANYPFCTIEPNVGRVAVPDPRLQALAAIGKSQKILPTSLEFVDIAGLVRGA
SRGEGLGNQFLANIREVDAIIHVLRCFEDDDITHVEGGIDPIRDAEIIETELMLADLDSLEKRIVALQKKAKGNDRDAAA
QVALMEPLIAVLREGRPARQAIPAGQEEAVRRLQLMTSKPVLYVCNVEEASAATGNEWSERVRARAEAEGAVAVVVSAAI
EAEVSQLGPEDRKEFLDGLGLSDSGLDRVIAAGYRLLGLRTYFTVGPKETRAWTITAGTRAPQAAAVIHNDFERGFIACE
TVAYDDYIRYQGEAGAKEAGKLRIEGRDYVVQDGDVLLFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=366, Percent_Identity=43.7158469945355, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=34.7639484978541, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1787454, Length=365, Percent_Identity=57.8082191780822, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=32.3076923076923, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=363, Percent_Identity=42.1487603305785, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=40.5405405405405, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=35.4330708661417, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321649, Length=161, Percent_Identity=36.6459627329193, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640873, Length=364, Percent_Identity=43.4065934065934, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24640877, Length=364, Percent_Identity=43.4065934065934, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24640875, Length=364, Percent_Identity=43.4065934065934, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=40.4907975460123, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24585318, Length=174, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39294; Mature: 39163

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNCGIVGLPNVGKSTLFNALTETASAQAANYPFCTIEPNVGRVAVPDPRLQALAAIGK
CCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCC
SQKILPTSLEFVDIAGLVRGASRGEGLGNQFLANIREVDAIIHVLRCFEDDDITHVEGGI
CCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
DPIRDAEIIETELMLADLDSLEKRIVALQKKAKGNDRDAAAQVALMEPLIAVLREGRPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
QAIPAGQEEAVRRLQLMTSKPVLYVCNVEEASAATGNEWSERVRARAEAEGAVAVVVSAA
HHCCCCHHHHHHHHHHHCCCCEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCEEEEHHHH
IEAEVSQLGPEDRKEFLDGLGLSDSGLDRVIAAGYRLLGLRTYFTVGPKETRAWTITAGT
HHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECC
RAPQAAAVIHNDFERGFIACETVAYDDYIRYQGEAGAKEAGKLRIEGRDYVVQDGDVLLF
CCCCHHHHHHCCCCCCEEEEEEEEECHHHEECCCCCCCCCCEEEECCCEEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure 
GFNCGIVGLPNVGKSTLFNALTETASAQAANYPFCTIEPNVGRVAVPDPRLQALAAIGK
CCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCC
SQKILPTSLEFVDIAGLVRGASRGEGLGNQFLANIREVDAIIHVLRCFEDDDITHVEGGI
CCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
DPIRDAEIIETELMLADLDSLEKRIVALQKKAKGNDRDAAAQVALMEPLIAVLREGRPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
QAIPAGQEEAVRRLQLMTSKPVLYVCNVEEASAATGNEWSERVRARAEAEGAVAVVVSAA
HHCCCCHHHHHHHHHHHCCCCEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCEEEEHHHH
IEAEVSQLGPEDRKEFLDGLGLSDSGLDRVIAAGYRLLGLRTYFTVGPKETRAWTITAGT
HHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECC
RAPQAAAVIHNDFERGFIACETVAYDDYIRYQGEAGAKEAGKLRIEGRDYVVQDGDVLLF
CCCCHHHHHHCCCCCCEEEEEEEEECHHHEECCCCCCCCCCEEEECCCEEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA