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The map label for this gene is 162146693

Identifier: 162146693

GI number: 162146693

Start: 888908

End: 889300

Strand: Direct

Name: 162146693

Synonym: GDI_0871

Alternate gene names: NA

Gene position: 888908-889300 (Clockwise)

Preceding gene: 162146692

Following gene: 162146694

Centisome position: 22.54

GC content: 66.67

Gene sequence:

>393_bases
ATGCGCTTTACCGTCGATCGGCTGGACCATGTCGTCATCACCGTCCGTGACCTGGAGGTCTCGGCGTCCTGGTACCAGCG
GGTGTTGGGCATGGAGCGCGAGGAATATGGCCGCAACAACCGTACGGCGCTGAAGTTCGGCGGCCAGAAGATCAACCTCC
GTCCCCATGGGGCGGAGGGCTGGTCCACCGCGACCGACGCGCTGCCCGGCACCAACGACCTGTGCTTCATCACCGCCGTG
GCCAGCGACGACGTAGTGGAACATCTGCAGGGATGCGGCGTGACGGTGACCGAGGGCCCGGTCGCCCGGCTGGGCGCGCT
GGGCCCCGTGACCTCGGTCTATTGCGAGGACCCGGACGGCAATCTGGTCGAGATCGCCTCCTACCAGGGATAG

Upstream 100 bases:

>100_bases
TCGTCATCGACGATAAGGGTAATGATTTCTACGAAGGCCTGACGGGCTGAGGCGGGGCGATTCGCCCCGTCACCCCTGGG
TCAAGGGAGACCTCCGTTCC

Downstream 100 bases:

>100_bases
CGCATGCCCGATGTCAGTCCGATCGCGCCGGCGGTTGACGACCCGACGCGGTATCCTCACCCCAACGACCGTCCGCTGGC
GGGCGAACCCCATCCCGACC

Product: glyoxalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MRFTVDRLDHVVITVRDLEVSASWYQRVLGMEREEYGRNNRTALKFGGQKINLRPHGAEGWSTATDALPGTNDLCFITAV
ASDDVVEHLQGCGVTVTEGPVARLGALGPVTSVYCEDPDGNLVEIASYQG

Sequences:

>Translated_130_residues
MRFTVDRLDHVVITVRDLEVSASWYQRVLGMEREEYGRNNRTALKFGGQKINLRPHGAEGWSTATDALPGTNDLCFITAV
ASDDVVEHLQGCGVTVTEGPVARLGALGPVTSVYCEDPDGNLVEIASYQG
>Mature_130_residues
MRFTVDRLDHVVITVRDLEVSASWYQRVLGMEREEYGRNNRTALKFGGQKINLRPHGAEGWSTATDALPGTNDLCFITAV
ASDDVVEHLQGCGVTVTEGPVARLGALGPVTSVYCEDPDGNLVEIASYQG

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=124, Percent_Identity=42.741935483871, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14124; Mature: 14124

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTVDRLDHVVITVRDLEVSASWYQRVLGMEREEYGRNNRTALKFGGQKINLRPHGAEG
CCEECCCCCEEEEEEEEEEECHHHHHHHHCCCHHHHCCCCCEEEEECCEEEEEEECCCCC
WSTATDALPGTNDLCFITAVASDDVVEHLQGCGVTVTEGPVARLGALGPVTSVYCEDPDG
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCEEECCCCHHHHCCCCCCCEEEEECCCC
NLVEIASYQG
CEEEEEECCC
>Mature Secondary Structure
MRFTVDRLDHVVITVRDLEVSASWYQRVLGMEREEYGRNNRTALKFGGQKINLRPHGAEG
CCEECCCCCEEEEEEEEEEECHHHHHHHHCCCHHHHCCCCCEEEEECCEEEEEEECCCCC
WSTATDALPGTNDLCFITAVASDDVVEHLQGCGVTVTEGPVARLGALGPVTSVYCEDPDG
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCEEECCCCHHHHCCCCCCCEEEEECCCC
NLVEIASYQG
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]