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The map label for this gene is moaB [H]

Identifier: 162146593

GI number: 162146593

Start: 788824

End: 789393

Strand: Direct

Name: moaB [H]

Synonym: GDI_0771

Alternate gene names: 162146593

Gene position: 788824-789393 (Clockwise)

Preceding gene: 162146592

Following gene: 162146594

Centisome position: 20.0

GC content: 67.02

Gene sequence:

>570_bases
GTGGTGGGGAACATGGATGCCATGTCCAGACTCGATCCCACCCGACCGTTCCTGCCAGTCCGTATCGCGGTGCTGACGGT
TTCCGATACGCGCGTATTGGAAACCGACACCTCCGGCGCCCTGCTCGTGCAGCGTATCGCTGCCGCCGGCCATCACCTGG
CCGACCGCGCCATCGAACCGGACGATGCCGACCGCATCGCGGCCCGTCTGGCGGGCTGGATCGCCGATCCCGCGATCGAC
GCGGTCATTTCCACCGGCGGCACCGGCGTCACGGGCCGCGACGTGACGCCCGAAGCCTTCGAACGGGTGCTGGAAAAGCG
GATCGAGGGCTTCGGTGAACTGTTCCGCATGCTGTCGTACCAGAAGATCGGGACGTCGACGATCCAGTCGCGCGCCCTGG
CCGGGGTCGCCAACGGCACTTACCTGTTCGCGCTGCCGGGGTCGTCCGGCGCGGTGAAGGACGGGTGGGACGACATCCTG
GTCTGGCAGTTGGACAGCCGCCACCGCCCCTGCAATTTCGTGGAACTGATGCCCCGCCTGCGGGAGCATCTGGAACCCGC
TCACGATTGA

Upstream 100 bases:

>100_bases
CGTGCCGCCGCGCGGCACTCTCGCTCACCAGACCACGTTTCCAGGCAGGCTTCGCCCACATGTTTCCTGCCGGGCGTGAA
GAGCGTTGACGGCAGTATCG

Downstream 100 bases:

>100_bases
AAGGTCATGCGATGACTGGCAATGCGATGACTGGCAAGAAGCTGCTTCTGCTGGCGGGCGATTACGTCGAAGATTACGAA
ATCATGGTGCCGTACCAGGC

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVGNMDAMSRLDPTRPFLPVRIAVLTVSDTRVLETDTSGALLVQRIAAAGHHLADRAIEPDDADRIAARLAGWIADPAID
AVISTGGTGVTGRDVTPEAFERVLEKRIEGFGELFRMLSYQKIGTSTIQSRALAGVANGTYLFALPGSSGAVKDGWDDIL
VWQLDSRHRPCNFVELMPRLREHLEPAHD

Sequences:

>Translated_189_residues
MVGNMDAMSRLDPTRPFLPVRIAVLTVSDTRVLETDTSGALLVQRIAAAGHHLADRAIEPDDADRIAARLAGWIADPAID
AVISTGGTGVTGRDVTPEAFERVLEKRIEGFGELFRMLSYQKIGTSTIQSRALAGVANGTYLFALPGSSGAVKDGWDDIL
VWQLDSRHRPCNFVELMPRLREHLEPAHD
>Mature_189_residues
MVGNMDAMSRLDPTRPFLPVRIAVLTVSDTRVLETDTSGALLVQRIAAAGHHLADRAIEPDDADRIAARLAGWIADPAID
AVISTGGTGVTGRDVTPEAFERVLEKRIEGFGELFRMLSYQKIGTSTIQSRALAGVANGTYLFALPGSSGAVKDGWDDIL
VWQLDSRHRPCNFVELMPRLREHLEPAHD

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=32.8767123287671, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=32.8767123287671, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787000, Length=157, Percent_Identity=51.5923566878981, Blast_Score=169, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17564954, Length=147, Percent_Identity=35.3741496598639, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136978, Length=146, Percent_Identity=36.986301369863, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=146, Percent_Identity=36.986301369863, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20573; Mature: 20573

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGNMDAMSRLDPTRPFLPVRIAVLTVSDTRVLETDTSGALLVQRIAAAGHHLADRAIEP
CCCCHHHHHHCCCCCCCCEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
DDADRIAARLAGWIADPAIDAVISTGGTGVTGRDVTPEAFERVLEKRIEGFGELFRMLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKIGTSTIQSRALAGVANGTYLFALPGSSGAVKDGWDDILVWQLDSRHRPCNFVELMPRL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
REHLEPAHD
HHHCCCCCC
>Mature Secondary Structure
MVGNMDAMSRLDPTRPFLPVRIAVLTVSDTRVLETDTSGALLVQRIAAAGHHLADRAIEP
CCCCHHHHHHCCCCCCCCEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
DDADRIAARLAGWIADPAIDAVISTGGTGVTGRDVTPEAFERVLEKRIEGFGELFRMLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKIGTSTIQSRALAGVANGTYLFALPGSSGAVKDGWDDILVWQLDSRHRPCNFVELMPRL
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
REHLEPAHD
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]