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The map label for this gene is ytfL [C]

Identifier: 162146546

GI number: 162146546

Start: 740752

End: 742038

Strand: Direct

Name: ytfL [C]

Synonym: GDI_0723

Alternate gene names: 162146546

Gene position: 740752-742038 (Clockwise)

Preceding gene: 162146545

Following gene: 162146548

Centisome position: 18.78

GC content: 67.99

Gene sequence:

>1287_bases
ATGATCGCGCCGCTTGTCGTCATTTTTCTCCTCGTTCTCATCAATGGCATCTTCGCCATGGGGGAACTGGCCCTGATCTC
GGCGCGCCGCACGCGCCTGATGATCATGCACCGCAGCGGGGTGAAGGGCGCCGAGCGGGCCCTGCGCCTGGCCGAGGACC
CGCAGAGCTTCCTGCCCACGGTGCAGGTCGGCATCACCCTGGTCTCGATCCTGGAAGGTACGTTCGGCGGCACGCAGATC
GAAGGGTACCTGACGCCCTGGCTGGCGCGGTTTCCGGCCTTGCGTCCGTTCGCCGCCGAACTGTCGATGACGGTCGTGGT
GGTGGCGATCACCTCGCTGATGCTGGTGCTGGGCGAACTGGTGCCCAAGCAGCTTGCGCTGCGCCATCCCGAAATCGTCG
CGGCGCGGCTATCGCTGCCGTTGGAAGGCCTGGCCCGCGTCACGCGCCCGGCCGTCTGGCTGCTGGGGCGGTCCTCGAAC
CTGGTGCTGCGCCTGATGGGCGTGGGCGCCATGACCCGCGAAGCCCTGACCGAGGAAGAACTGAAGGCCTATATCGCCGA
AGGCGCGCAGTCCGGCGTGCTGGAGCAGGAGGAGCGCGACATGATCGAGCGCCTGCTGCGCCTGGCGGACCGGCCGGTCC
GTGCCATCATGACGCCGCGCAACGAACTGTTCTGGATCGAACGCCACGCCAGCCGCGAGGAACTGCGCCGTACCCTGCGC
AACACCGTCTATACCCGCATCGTGGTCTGCGACGGCGGGGTCGACAATCCGGTGGGCGTCATCCTGGCGAAGGACATGCT
GGACCGCCTGCTGGACGGGCGGCCGGTCACGATCGAATCGGGGCTGCGCAAGCCCGTGGTGGTCCCCGACACGATCTCGG
CCTTCGACATGGTCGAACGGATGCGCACCGTGCCTCTGGGCATCGCGCTGGTGCTGGACGAATACGGGTCGTTCGAAGGG
ATCGTGACCGCCTCGGACCTGTTCGAGGCCATCGTGGGCGAACACCACGAACCGGGCAGCACCCCCAAGAAGCGCATGGC
GCAGGACGACGTGCTGATCCTGGACGGCTTCATGCCCGCCGACGAGGTCAAGGACCGCCTGGGCCTGTCCGACCTGCCGG
ACGAAGGCAGCTACCACACGCTGGGCGGCCTGATCCTGGCGCTGCTGCGCCGCGTGCCGGCGACGGGGGACAAGGTCGTG
TTTTCCGGCTGGCTGTTCGAGGTCCTGGAGACCGACCAGCGGCGGGTCGTGAAGGTCCGGGCCAGCCGTCAGGCGCTGGC
GGACTGA

Upstream 100 bases:

>100_bases
CTGAAGTGGCGGGGCTTGTCCCCGCCATTTTCATATTCATCGCGTCTTTTTTGCCACAGTTCGGATTGCTTCCGCCGATT
GGTATAAGATCGCTTCCATC

Downstream 100 bases:

>100_bases
ACCGCCCGGGTCCAGGCCGCCCTTCCGGGCCGACCTTCAGTGTATGGTGTGGAAGTGGCGGCCGGCCAGGTCCTGCTCGG
CGGCGAAGGCGGGCCATTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MIAPLVVIFLLVLINGIFAMGELALISARRTRLMIMHRSGVKGAERALRLAEDPQSFLPTVQVGITLVSILEGTFGGTQI
EGYLTPWLARFPALRPFAAELSMTVVVVAITSLMLVLGELVPKQLALRHPEIVAARLSLPLEGLARVTRPAVWLLGRSSN
LVLRLMGVGAMTREALTEEELKAYIAEGAQSGVLEQEERDMIERLLRLADRPVRAIMTPRNELFWIERHASREELRRTLR
NTVYTRIVVCDGGVDNPVGVILAKDMLDRLLDGRPVTIESGLRKPVVVPDTISAFDMVERMRTVPLGIALVLDEYGSFEG
IVTASDLFEAIVGEHHEPGSTPKKRMAQDDVLILDGFMPADEVKDRLGLSDLPDEGSYHTLGGLILALLRRVPATGDKVV
FSGWLFEVLETDQRRVVKVRASRQALAD

Sequences:

>Translated_428_residues
MIAPLVVIFLLVLINGIFAMGELALISARRTRLMIMHRSGVKGAERALRLAEDPQSFLPTVQVGITLVSILEGTFGGTQI
EGYLTPWLARFPALRPFAAELSMTVVVVAITSLMLVLGELVPKQLALRHPEIVAARLSLPLEGLARVTRPAVWLLGRSSN
LVLRLMGVGAMTREALTEEELKAYIAEGAQSGVLEQEERDMIERLLRLADRPVRAIMTPRNELFWIERHASREELRRTLR
NTVYTRIVVCDGGVDNPVGVILAKDMLDRLLDGRPVTIESGLRKPVVVPDTISAFDMVERMRTVPLGIALVLDEYGSFEG
IVTASDLFEAIVGEHHEPGSTPKKRMAQDDVLILDGFMPADEVKDRLGLSDLPDEGSYHTLGGLILALLRRVPATGDKVV
FSGWLFEVLETDQRRVVKVRASRQALAD
>Mature_428_residues
MIAPLVVIFLLVLINGIFAMGELALISARRTRLMIMHRSGVKGAERALRLAEDPQSFLPTVQVGITLVSILEGTFGGTQI
EGYLTPWLARFPALRPFAAELSMTVVVVAITSLMLVLGELVPKQLALRHPEIVAARLSLPLEGLARVTRPAVWLLGRSSN
LVLRLMGVGAMTREALTEEELKAYIAEGAQSGVLEQEERDMIERLLRLADRPVRAIMTPRNELFWIERHASREELRRTLR
NTVYTRIVVCDGGVDNPVGVILAKDMLDRLLDGRPVTIESGLRKPVVVPDTISAFDMVERMRTVPLGIALVLDEYGSFEG
IVTASDLFEAIVGEHHEPGSTPKKRMAQDDVLILDGFMPADEVKDRLGLSDLPDEGSYHTLGGLILALLRRVPATGDKVV
FSGWLFEVLETDQRRVVKVRASRQALAD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=376, Percent_Identity=26.3297872340426, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1790664, Length=425, Percent_Identity=27.2941176470588, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI87082033, Length=333, Percent_Identity=29.1291291291291, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI145693175, Length=431, Percent_Identity=25.0580046403712, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788119, Length=347, Percent_Identity=26.2247838616715, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786879, Length=251, Percent_Identity=27.4900398406374, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47242; Mature: 47242

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPLVVIFLLVLINGIFAMGELALISARRTRLMIMHRSGVKGAERALRLAEDPQSFLPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCHHHHCCH
VQVGITLVSILEGTFGGTQIEGYLTPWLARFPALRPFAAELSMTVVVVAITSLMLVLGEL
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VPKQLALRHPEIVAARLSLPLEGLARVTRPAVWLLGRSSNLVLRLMGVGAMTREALTEEE
HHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCEEEEEECCCHHHHHHHHHHH
LKAYIAEGAQSGVLEQEERDMIERLLRLADRPVRAIMTPRNELFWIERHASREELRRTLR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEHHHCCHHHHHHHHH
NTVYTRIVVCDGGVDNPVGVILAKDMLDRLLDGRPVTIESGLRKPVVVPDTISAFDMVER
HHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEHHCCCCCCEECCCCHHHHHHHHH
MRTVPLGIALVLDEYGSFEGIVTASDLFEAIVGEHHEPGSTPKKRMAQDDVLILDGFMPA
HHHCCHHHHHEEHHCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCH
DEVKDRLGLSDLPDEGSYHTLGGLILALLRRVPATGDKVVFSGWLFEVLETDQRRVVKVR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHH
ASRQALAD
HHHHHCCC
>Mature Secondary Structure
MIAPLVVIFLLVLINGIFAMGELALISARRTRLMIMHRSGVKGAERALRLAEDPQSFLPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCHHHHCCH
VQVGITLVSILEGTFGGTQIEGYLTPWLARFPALRPFAAELSMTVVVVAITSLMLVLGEL
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VPKQLALRHPEIVAARLSLPLEGLARVTRPAVWLLGRSSNLVLRLMGVGAMTREALTEEE
HHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCEEEEEECCCHHHHHHHHHHH
LKAYIAEGAQSGVLEQEERDMIERLLRLADRPVRAIMTPRNELFWIERHASREELRRTLR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEHHHCCHHHHHHHHH
NTVYTRIVVCDGGVDNPVGVILAKDMLDRLLDGRPVTIESGLRKPVVVPDTISAFDMVER
HHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEHHCCCCCCEECCCCHHHHHHHHH
MRTVPLGIALVLDEYGSFEGIVTASDLFEAIVGEHHEPGSTPKKRMAQDDVLILDGFMPA
HHHCCHHHHHEEHHCCCCCCEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCH
DEVKDRLGLSDLPDEGSYHTLGGLILALLRRVPATGDKVVFSGWLFEVLETDQRRVVKVR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHHHHHH
ASRQALAD
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]