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The map label for this gene is atpH

Identifier: 162146517

GI number: 162146517

Start: 704449

End: 705045

Strand: Direct

Name: atpH

Synonym: GDI_0693

Alternate gene names: 162146517

Gene position: 704449-705045 (Clockwise)

Preceding gene: 162146516

Following gene: 162146518

Centisome position: 17.86

GC content: 68.51

Gene sequence:

>597_bases
ATGGAAAGGCCGACCGTGGTTTCGGGTGGAACGACAACAATATCGATCGCCTCCGTCGCCAATGGCCTTCCGGGTCGTTA
CGCAACGGCACTCTATGAACTGGCCGCCGACCGGTGGCTGCTGAACGAGGTCCTGCCCCAGGCCGAGGCCCTGCGCGGCC
TGATCGACGGCAACGCCGATTTCCGGGCCCTTCTGAGCGACCGCACCCTCGACATCAAGGACATCACCCGCGCGCTGCTG
GCGGTGCTCGATGCCCAGGGGTTCGGCGCAACCATCCGCCATTTCGTGGGCGTCATCGCCCGCAACCGCCGCCTGTCCCA
GCTGCCGGCCATCCTCGACGCGCTGCGGGCGATCGCCGCCGCCAAGCGCGGGGAAGAGGTGGCTGAAGTTGTCTCGGCCC
AGCCCCTGACGGACTTGCAGCGCGTCCAGCTTCAAAGCCGCCTCGCCGAGGCCGGCTATTCCAGGGTCAACATTCAGGAG
CGTGTCGATGCGGCGCTGCTGGGCGGCCTGGTCGTGCGCGTCGGCGCGCGCCTGTACGACACCAGCCTCCGGTCCCGCCT
GACCCGCCTGCACCACGCCATGAAGGGAGCCGCGTGA

Upstream 100 bases:

>100_bases
GGCGGCATGCTAGACGCCCCGCCAACGATGGACAGGACATGAAACGGCGGACAGGACCGATTCCGGGGCCGCCGCACGTC
ATAATGTTCAGGATCTTGGG

Downstream 100 bases:

>100_bases
TGGAAATCCGCCCCGCCGAGATTTCGGATATCCTCAAGCAGCAGATCGCCACGTTCGACACGCCGGTTGATATTGCCGAG
ACGGGCACGATCCTGTCGGT

Product: ATP synthase delta chain

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MERPTVVSGGTTTISIASVANGLPGRYATALYELAADRWLLNEVLPQAEALRGLIDGNADFRALLSDRTLDIKDITRALL
AVLDAQGFGATIRHFVGVIARNRRLSQLPAILDALRAIAAAKRGEEVAEVVSAQPLTDLQRVQLQSRLAEAGYSRVNIQE
RVDAALLGGLVVRVGARLYDTSLRSRLTRLHHAMKGAA

Sequences:

>Translated_198_residues
MERPTVVSGGTTTISIASVANGLPGRYATALYELAADRWLLNEVLPQAEALRGLIDGNADFRALLSDRTLDIKDITRALL
AVLDAQGFGATIRHFVGVIARNRRLSQLPAILDALRAIAAAKRGEEVAEVVSAQPLTDLQRVQLQSRLAEAGYSRVNIQE
RVDAALLGGLVVRVGARLYDTSLRSRLTRLHHAMKGAA
>Mature_198_residues
MERPTVVSGGTTTISIASVANGLPGRYATALYELAADRWLLNEVLPQAEALRGLIDGNADFRALLSDRTLDIKDITRALL
AVLDAQGFGATIRHFVGVIARNRRLSQLPAILDALRAIAAAKRGEEVAEVVSAQPLTDLQRVQLQSRLAEAGYSRVNIQE
RVDAALLGGLVVRVGARLYDTSLRSRLTRLHHAMKGAA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=180, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984710, Length=176, Percent_Identity=28.9772727272727, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71984717, Length=176, Percent_Identity=28.9772727272727, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647054, Length=179, Percent_Identity=32.9608938547486, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24647056, Length=113, Percent_Identity=34.5132743362832, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_GLUDA (A9H9A1)

Other databases:

- EMBL:   CP001189
- EMBL:   AM889285
- RefSeq:   YP_001600976.1
- RefSeq:   YP_002275713.1
- ProteinModelPortal:   A9H9A1
- SMR:   A9H9A1
- GeneID:   5790135
- GeneID:   6974721
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1316
- HOGENOM:   HBG668108
- OMA:   SIGDKYV
- ProtClustDB:   CLSK2402799
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 21344; Mature: 21344

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPTVVSGGTTTISIASVANGLPGRYATALYELAADRWLLNEVLPQAEALRGLIDGNAD
CCCCCEEECCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCH
FRALLSDRTLDIKDITRALLAVLDAQGFGATIRHFVGVIARNRRLSQLPAILDALRAIAA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKRGEEVAEVVSAQPLTDLQRVQLQSRLAEAGYSRVNIQERVDAALLGGLVVRVGARLYD
HHCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSLRSRLTRLHHAMKGAA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERPTVVSGGTTTISIASVANGLPGRYATALYELAADRWLLNEVLPQAEALRGLIDGNAD
CCCCCEEECCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCH
FRALLSDRTLDIKDITRALLAVLDAQGFGATIRHFVGVIARNRRLSQLPAILDALRAIAA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKRGEEVAEVVSAQPLTDLQRVQLQSRLAEAGYSRVNIQERVDAALLGGLVVRVGARLYD
HHCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSLRSRLTRLHHAMKGAA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA