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The map label for this gene is crt [H]

Identifier: 162146503

GI number: 162146503

Start: 688827

End: 689654

Strand: Reverse

Name: crt [H]

Synonym: GDI_0679

Alternate gene names: 162146503

Gene position: 689654-688827 (Counterclockwise)

Preceding gene: 162146504

Following gene: 162146500

Centisome position: 17.49

GC content: 71.38

Gene sequence:

>828_bases
GTGACCGGCGCGAGAGACGGGCACGCCGGTCACGGCGCGACAGACGAGCGCGCCGCCGCCGGCCGGGTTCGGCTGGCGAT
CGACCAGGACGTGGCCCACATCACCTTCGACCGGCCGGCGGCGCGCAATGCGATGACGTGGGCGATGTATGCCGATCTGG
CGGACGCGATCGCGCGGATCGGCGATACGCCCTCGGTCCGGATCGCTGTCCTGCGCGGCGCGGGGGGCAAGGCCTTCGTG
GCCGGCACCGACATCGCGCAGTTCCACGCCTTCCGCACGGGCGAGGACGGCGTGGCGTACGAACGGAAGATCGATTCCTG
CATCACGGCATTGGATCGGATCGGCGTGCCCACCCTGGCGGTCGTCGAGGGCTATGCCGTGGGCGGTGGACTGGCGATCG
CCAATGCCTGCGATTTCCGCATCGCGGCGGCGGGGGCCCGGTTCGGGGTGCCCATCGCGCGCACGTTGGGCAACTGCCTG
TCGGCGGCGAATGTCGCGCGGCTGGAACGGGGGCTGGGCGTGGCCTGGGTCAAGCGGATGCTGCTGCTGGCCGAAATGCC
GACCGCCGAGGACCTGGCGCCGACGGGCTATCTGTGTGCCGTCACCGCGCCCGGGGAACTGGACGGTGCCGTCAGCAGGA
TCTGCCGCCGGATTTGCGACCATGCCCCCATCACCATCGACGTCACACGGGAAACGGTACGCCGGCTGGAAGGCGGCGCG
GCGCCGGATATCTCCGACCTCATCAGCCGCTGCTACGGCAGCGCCGACTTCCATCGCGGGGTCGCGGCGTTCGGAACCGG
CACGCCCCCGCGATGGGAGGGGCGCTGA

Upstream 100 bases:

>100_bases
CCCCGCCGCTGCTGGGCCAGCACACGCACGAGGTCCTGGCCGAACGCGGCCTGTCGGATGACGCCATCGCGACCCTGGCG
GCCGAGGGGGCCTTCGCGCC

Downstream 100 bases:

>100_bases
GAAGAATCCTAACGGAAATCCCGGGCGGGAATAACCGGTACCATTCCCGCCCGCAGGTCCGCGCGGCCGATTTCCGACAG
CAGGGGGGTCAGGTCTTCCA

Product: 3-hydroxybutyryl-CoA dehydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTGARDGHAGHGATDERAAAGRVRLAIDQDVAHITFDRPAARNAMTWAMYADLADAIARIGDTPSVRIAVLRGAGGKAFV
AGTDIAQFHAFRTGEDGVAYERKIDSCITALDRIGVPTLAVVEGYAVGGGLAIANACDFRIAAAGARFGVPIARTLGNCL
SAANVARLERGLGVAWVKRMLLLAEMPTAEDLAPTGYLCAVTAPGELDGAVSRICRRICDHAPITIDVTRETVRRLEGGA
APDISDLISRCYGSADFHRGVAAFGTGTPPRWEGR

Sequences:

>Translated_275_residues
MTGARDGHAGHGATDERAAAGRVRLAIDQDVAHITFDRPAARNAMTWAMYADLADAIARIGDTPSVRIAVLRGAGGKAFV
AGTDIAQFHAFRTGEDGVAYERKIDSCITALDRIGVPTLAVVEGYAVGGGLAIANACDFRIAAAGARFGVPIARTLGNCL
SAANVARLERGLGVAWVKRMLLLAEMPTAEDLAPTGYLCAVTAPGELDGAVSRICRRICDHAPITIDVTRETVRRLEGGA
APDISDLISRCYGSADFHRGVAAFGTGTPPRWEGR
>Mature_274_residues
TGARDGHAGHGATDERAAAGRVRLAIDQDVAHITFDRPAARNAMTWAMYADLADAIARIGDTPSVRIAVLRGAGGKAFVA
GTDIAQFHAFRTGEDGVAYERKIDSCITALDRIGVPTLAVVEGYAVGGGLAIANACDFRIAAAGARFGVPIARTLGNCLS
AANVARLERGLGVAWVKRMLLLAEMPTAEDLAPTGYLCAVTAPGELDGAVSRICRRICDHAPITIDVTRETVRRLEGGAA
PDISDLISRCYGSADFHRGVAAFGTGTPPRWEGR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=242, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=28.2352941176471, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=27.4809160305344, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI221142681, Length=265, Percent_Identity=27.5471698113208, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788597, Length=206, Percent_Identity=25.2427184466019, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790281, Length=149, Percent_Identity=30.8724832214765, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=22.7848101265823, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=216, Percent_Identity=24.537037037037, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=210, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=26.4423076923077, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=24.8062015503876, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=25.0996015936255, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28798; Mature: 28667

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGARDGHAGHGATDERAAAGRVRLAIDQDVAHITFDRPAARNAMTWAMYADLADAIARI
CCCCCCCCCCCCCCCCHHHCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GDTPSVRIAVLRGAGGKAFVAGTDIAQFHAFRTGEDGVAYERKIDSCITALDRIGVPTLA
CCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
VVEGYAVGGGLAIANACDFRIAAAGARFGVPIARTLGNCLSAANVARLERGLGVAWVKRM
HHCCEECCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLAEMPTAEDLAPTGYLCAVTAPGELDGAVSRICRRICDHAPITIDVTRETVRRLEGGA
HHHHCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCC
APDISDLISRCYGSADFHRGVAAFGTGTPPRWEGR
CCCHHHHHHHHCCCCHHHCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
TGARDGHAGHGATDERAAAGRVRLAIDQDVAHITFDRPAARNAMTWAMYADLADAIARI
CCCCCCCCCCCCCCCHHHCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GDTPSVRIAVLRGAGGKAFVAGTDIAQFHAFRTGEDGVAYERKIDSCITALDRIGVPTLA
CCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
VVEGYAVGGGLAIANACDFRIAAAGARFGVPIARTLGNCLSAANVARLERGLGVAWVKRM
HHCCEECCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLAEMPTAEDLAPTGYLCAVTAPGELDGAVSRICRRICDHAPITIDVTRETVRRLEGGA
HHHHCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCC
APDISDLISRCYGSADFHRGVAAFGTGTPPRWEGR
CCCHHHHHHHHCCCCHHHCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]