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The map label for this gene is fabG [H]

Identifier: 162146499

GI number: 162146499

Start: 682424

End: 683290

Strand: Direct

Name: fabG [H]

Synonym: GDI_0675

Alternate gene names: 162146499

Gene position: 682424-683290 (Clockwise)

Preceding gene: 162146498

Following gene: 162146501

Centisome position: 17.3

GC content: 72.32

Gene sequence:

>867_bases
GTGACCGATACTGCCGAGATCCTGGCTTCTCCCGCGCCCGCCGTTGCCGATGGGGGGCGGCCCCTGGCGGTCGTGACCGG
CGGGACGGGCGGGATCGGGCGGCGGGTGGTGGAATTGCTGGCCGGGGCCGGTTACCGGGTGACGGTCCTGTCGCGCCAGG
GTGCGATGGCCGGCGCGATGGCCGGCGCGGGGTTCGCGGACGACATGCCCGTTACGCTGCGGGCCTGCGATCTGGGACGG
GCCGAATCGATCGCGGCGGCATCCTCGGCCATCCTGGCGCAGGATGGGCCGGTCAGCCTGCTGGTCCATTGCGCCGGGGT
GATCCATCCCGGGGACAGCGCCGCGCAGGGCGCGGACGAACTGGCCGCGCAGGTCGCGGTCAACCTGACGGGGCCGATCG
ACCTGACGGCGCGCCTGCTGGGGCGGATGCAGCGCGGCGGGCATGTCGTCTTCGTCAATTCCATGGCCGGCGCGCTGCCG
CTGGCGGGCTGCGGGGCCTATACGGCCGCGAAATTCGGCCTGCGTGGCTATGCGATGTGTCTGGCGCGGGAGGTCCGGAA
ACAGGGAATCCGTGTCTCGTCCGTCTTTCCCGCTGCCGTGGATACGCCGATGCTGCGCCGGGAAATGGCCGAGGGAGGAT
CGGTCCTGAATTTCGTCAGCGCCCCGGCCGACCCGGACCACGTCGCACGCCGCATCGTGCGGATCTGCCGCCATCCCCGG
CGGGAAACCTTCCTGCCGGCCATGGACGGGCTGTTCGCCAATCTCTGCCTGCTGCTGCCCCGGCTGCTGGACCTGGCCCT
GCCGGTCCTGACCCTGGCCGGCCGGCTGGGCTACCGGCGTTTCGTCCGGCGCGGCGGCGGCAGGTAG

Upstream 100 bases:

>100_bases
CCCTGTCGGACAACCGGCCCGGTTTGCGTTGCACCGTCATCCTGCCGCATATCGCCTCGATTGACCCAACCGACGGGCCG
ACTCGCCTGGGGGACAGATA

Downstream 100 bases:

>100_bases
GCGCGGGCGGCGAATTCCGCTTTCCCACGGGCAATTTGTTCACTATATGTTCTTCTCTTGGAGGGGAGAATGACCGGAAC
GGAGCGCACTGACCTGCTGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTDTAEILASPAPAVADGGRPLAVVTGGTGGIGRRVVELLAGAGYRVTVLSRQGAMAGAMAGAGFADDMPVTLRACDLGR
AESIAAASSAILAQDGPVSLLVHCAGVIHPGDSAAQGADELAAQVAVNLTGPIDLTARLLGRMQRGGHVVFVNSMAGALP
LAGCGAYTAAKFGLRGYAMCLAREVRKQGIRVSSVFPAAVDTPMLRREMAEGGSVLNFVSAPADPDHVARRIVRICRHPR
RETFLPAMDGLFANLCLLLPRLLDLALPVLTLAGRLGYRRFVRRGGGR

Sequences:

>Translated_288_residues
MTDTAEILASPAPAVADGGRPLAVVTGGTGGIGRRVVELLAGAGYRVTVLSRQGAMAGAMAGAGFADDMPVTLRACDLGR
AESIAAASSAILAQDGPVSLLVHCAGVIHPGDSAAQGADELAAQVAVNLTGPIDLTARLLGRMQRGGHVVFVNSMAGALP
LAGCGAYTAAKFGLRGYAMCLAREVRKQGIRVSSVFPAAVDTPMLRREMAEGGSVLNFVSAPADPDHVARRIVRICRHPR
RETFLPAMDGLFANLCLLLPRLLDLALPVLTLAGRLGYRRFVRRGGGR
>Mature_287_residues
TDTAEILASPAPAVADGGRPLAVVTGGTGGIGRRVVELLAGAGYRVTVLSRQGAMAGAMAGAGFADDMPVTLRACDLGRA
ESIAAASSAILAQDGPVSLLVHCAGVIHPGDSAAQGADELAAQVAVNLTGPIDLTARLLGRMQRGGHVVFVNSMAGALPL
AGCGAYTAAKFGLRGYAMCLAREVRKQGIRVSSVFPAAVDTPMLRREMAEGGSVLNFVSAPADPDHVARRIVRICRHPRR
ETFLPAMDGLFANLCLLLPRLLDLALPVLTLAGRLGYRRFVRRGGGR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=185, Percent_Identity=33.5135135135135, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4503817, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI20149619, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=31.1475409836066, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=32.1052631578947, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=26.7379679144385, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=193, Percent_Identity=32.1243523316062, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=31.9587628865979, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=196, Percent_Identity=31.6326530612245, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.2083333333333, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364892, Length=247, Percent_Identity=26.7206477732794, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355631, Length=251, Percent_Identity=25.8964143426295, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=223, Percent_Identity=27.8026905829596, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007234, Length=202, Percent_Identity=30.6930693069307, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24663911, Length=202, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29770; Mature: 29639

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTAEILASPAPAVADGGRPLAVVTGGTGGIGRRVVELLAGAGYRVTVLSRQGAMAGAM
CCCCHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AGAGFADDMPVTLRACDLGRAESIAAASSAILAQDGPVSLLVHCAGVIHPGDSAAQGADE
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHCCHHH
LAAQVAVNLTGPIDLTARLLGRMQRGGHVVFVNSMAGALPLAGCGAYTAAKFGLRGYAMC
HHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAREVRKQGIRVSSVFPAAVDTPMLRREMAEGGSVLNFVSAPADPDHVARRIVRICRHPR
HHHHHHHCCCEEEEECCHHHCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCC
RETFLPAMDGLFANLCLLLPRLLDLALPVLTLAGRLGYRRFVRRGGGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDTAEILASPAPAVADGGRPLAVVTGGTGGIGRRVVELLAGAGYRVTVLSRQGAMAGAM
CCCHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AGAGFADDMPVTLRACDLGRAESIAAASSAILAQDGPVSLLVHCAGVIHPGDSAAQGADE
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHCCHHH
LAAQVAVNLTGPIDLTARLLGRMQRGGHVVFVNSMAGALPLAGCGAYTAAKFGLRGYAMC
HHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAREVRKQGIRVSSVFPAAVDTPMLRREMAEGGSVLNFVSAPADPDHVARRIVRICRHPR
HHHHHHHCCCEEEEECCHHHCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCC
RETFLPAMDGLFANLCLLLPRLLDLALPVLTLAGRLGYRRFVRRGGGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534249 [H]