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The map label for this gene is aroD [H]

Identifier: 162146437

GI number: 162146437

Start: 620795

End: 621601

Strand: Direct

Name: aroD [H]

Synonym: GDI_0612

Alternate gene names: 162146437

Gene position: 620795-621601 (Clockwise)

Preceding gene: 162146436

Following gene: 162146438

Centisome position: 15.74

GC content: 72.49

Gene sequence:

>807_bases
GTGCCCGTGCGGGGCGTGACGCTGGGCGTCGGCCGCGCGGCGGTGATCGTGCCGATCGTCGCCGCCGGGGCGGACGAGGT
CCGGGCCGCCGCCCGCCGCCTGGCCGGCCACGACGCGGTGGACCTGGTCGAGGCCCGGGCCGATCACTGGCATGACGCGC
GCCCGGGGCATGACGGTCACGGCGCGCGCGTCACCGCCCTGTGCCGCGACCTGCGGGCGATCCTGGACCGTCGCGGGCTG
ATCGTGACCTTTCGCACCGGGGCGGAGGGCGGCGCGACCCCGATCGATGACGAGGCCTATGTCGCCTTCTACGACCACGT
GCTGGAGGCCGACCTGCTGCCGGACCTGATCGACGTCGAATTCAATCGCGGCCGGGACGTCGTGCGGCGCATCGTCGCGG
CGGCGCGGGCCGCGGGCGTGCGCGTCATCCTGTCGTCCCATGACTTCGCCGGTACCGGTCCGTCCCATCGCCTGGTGGAG
CGCATGCGCAGGATGCAGGAGTGCGACGTGGATGTCCTGAAGCTCGCGGTCATGCCGCATGACGCGGGGGACGTGCTCAG
CCTGCTGGCCGCCACGTATGAAATGCGCACACGCTGGGCCGACCGGCCGCTGATCACCATGGCGATGGGCGGAAGCGGCG
TCGTCTCGCGCCTGGCGGGTGAAATCTTCGGCTCGGCCGCGACCTTCGGCATGCTGGACCATCCCTCGGCACCGGGGCAG
ATCGATGCCCGCGACCTGCGGCATTGTGTCGAAATCGTCCATCACGCCGTCGCCCCCAGCCTGCGGACAGCCGGGACGGG
CCGCTGA

Upstream 100 bases:

>100_bases
CTGCTGGACCAGTTGGCGGGGAGCACGGTCCATGCGTAGCGCGAAGGACCACGCCCCGGACGAACCGGAACCCTTGGCGC
CGGGGCCGAAACTGCGCGCC

Downstream 100 bases:

>100_bases
CGGTGCGCGACAATGTGACACGCGCCGGTGCCAGGGGTGGGCCGTTTCTCTTGACCCGCCGCGTTCCCCCCGCTCTAAGA
TCGTCGCGTTCTCCGGGGAG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPVRGVTLGVGRAAVIVPIVAAGADEVRAAARRLAGHDAVDLVEARADHWHDARPGHDGHGARVTALCRDLRAILDRRGL
IVTFRTGAEGGATPIDDEAYVAFYDHVLEADLLPDLIDVEFNRGRDVVRRIVAAARAAGVRVILSSHDFAGTGPSHRLVE
RMRRMQECDVDVLKLAVMPHDAGDVLSLLAATYEMRTRWADRPLITMAMGGSGVVSRLAGEIFGSAATFGMLDHPSAPGQ
IDARDLRHCVEIVHHAVAPSLRTAGTGR

Sequences:

>Translated_268_residues
MPVRGVTLGVGRAAVIVPIVAAGADEVRAAARRLAGHDAVDLVEARADHWHDARPGHDGHGARVTALCRDLRAILDRRGL
IVTFRTGAEGGATPIDDEAYVAFYDHVLEADLLPDLIDVEFNRGRDVVRRIVAAARAAGVRVILSSHDFAGTGPSHRLVE
RMRRMQECDVDVLKLAVMPHDAGDVLSLLAATYEMRTRWADRPLITMAMGGSGVVSRLAGEIFGSAATFGMLDHPSAPGQ
IDARDLRHCVEIVHHAVAPSLRTAGTGR
>Mature_267_residues
PVRGVTLGVGRAAVIVPIVAAGADEVRAAARRLAGHDAVDLVEARADHWHDARPGHDGHGARVTALCRDLRAILDRRGLI
VTFRTGAEGGATPIDDEAYVAFYDHVLEADLLPDLIDVEFNRGRDVVRRIVAAARAAGVRVILSSHDFAGTGPSHRLVER
MRRMQECDVDVLKLAVMPHDAGDVLSLLAATYEMRTRWADRPLITMAMGGSGVVSRLAGEIFGSAATFGMLDHPSAPGQI
DARDLRHCVEIVHHAVAPSLRTAGTGR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=255, Percent_Identity=42.3529411764706, Blast_Score=200, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 28726; Mature: 28595

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRGVTLGVGRAAVIVPIVAAGADEVRAAARRLAGHDAVDLVEARADHWHDARPGHDGH
CCCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
GARVTALCRDLRAILDRRGLIVTFRTGAEGGATPIDDEAYVAFYDHVLEADLLPDLIDVE
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCC
FNRGRDVVRRIVAAARAAGVRVILSSHDFAGTGPSHRLVERMRRMQECDVDVLKLAVMPH
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEECCC
DAGDVLSLLAATYEMRTRWADRPLITMAMGGSGVVSRLAGEIFGSAATFGMLDHPSAPGQ
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCCCCCC
IDARDLRHCVEIVHHAVAPSLRTAGTGR
CCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PVRGVTLGVGRAAVIVPIVAAGADEVRAAARRLAGHDAVDLVEARADHWHDARPGHDGH
CCCCEEECCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
GARVTALCRDLRAILDRRGLIVTFRTGAEGGATPIDDEAYVAFYDHVLEADLLPDLIDVE
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCC
FNRGRDVVRRIVAAARAAGVRVILSSHDFAGTGPSHRLVERMRRMQECDVDVLKLAVMPH
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEECCC
DAGDVLSLLAATYEMRTRWADRPLITMAMGGSGVVSRLAGEIFGSAATFGMLDHPSAPGQ
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCCCCCC
IDARDLRHCVEIVHHAVAPSLRTAGTGR
CCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA