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The map label for this gene is nahA [H]

Identifier: 162146431

GI number: 162146431

Start: 613283

End: 615313

Strand: Direct

Name: nahA [H]

Synonym: GDI_0606

Alternate gene names: 162146431

Gene position: 613283-615313 (Clockwise)

Preceding gene: 162146430

Following gene: 162146435

Centisome position: 15.55

GC content: 71.69

Gene sequence:

>2031_bases
ATGCCGCTGCCCGCCTCGGCGCATTATTCCGGCCAGACCCTGTCCCTGGCCAACGGCCTGGCCGTGCAGTGGGACCACGC
GCCGACACCCCTGCTGCGCCGCGCGGCCGATCGGCTGAGGGCACGCCTGGACCGGCTGGCCGGCCGGGTGCTGCCGGCCG
ACGACCACGCGTCGGGGGCCGCGATGCTGCGGGTCCGCTACGGGGCCGACCCGTCCTTCCTCGCCCTGGGCGAGAAGGAG
CAGTACCGCCTGGCCGTCCGTCCGGACGGCATCACGCTGGACGCCGCCGGTCCCGCCGGGGTGCTGGACGGGTTCGCCAC
CCTGGCGCAACTGGCGGCGCAGGGGCCGCAGGGCCCGGTGCTGATGCAGGCCGATATCGACGACCGGCCGCGCTTTCCCT
GGCGCGGCATCATGATCGACGTCTCGCGCCACTTCATGCGCATCGAGACCCTGCATCGGCAGATCGACGCGATGGAGCAG
GTGAAGCTGAACGTGCTGCACCTGCATCTGGGCGATTCCCAGGGATTTCGGGTCGAAAGCCGGCTGTTCCCGGGCCTGCA
GCGGCAGGGGTCGCATGGCCAGTTCTATACCCAGGCCCAGATCCGCGACCTGGTCGCCTACGCCGCCGATCGCGGCGTGC
GCATCGTGCCGGAATTCGACACGCCCGGCCACGCGCTGGCCATCCTGCTGGCCTATCCCGCGCTGGCGGCCCAGCCGGTC
GATCCGGCCATGCCGGACCCCGACGACGCGGCGCTGAACCCGACGCTGGATGCCACGCTGCACTTCGTCACGCAGCTATA
CGGCGAAATGGGGCGCCTGTTCTCGGATCGCTATTTCCATGCCGGCGGCGATGAGGTGCAGGCCGAACAATGGACCCGCA
ATCCGAAGATTACGGCGTTCATGAAGGCCCACGGCTTCGCGGACACCGCGTCGCTGCAGGCGGCCTTTACCGCGCGGGTG
CAATCCGTGCTGGCCCGCCAGGGCAAGATCATGGTGGGCTGGGACGAGGTCAGCGCGGCCCCGATTCCCAAAAGCGTGGT
GGTCGAGGCCTGGCGGTCGTCCAAATTCATCGGCACCGCCACCCGGGCGGGCCACCCGGTCGTGGTCTCGGCCGGCTATT
ATCTCGACCTGCTGAACCCGGCGGAGCAGCATTACCGGGTCGATCCGCTGGACGTGCAGGCCAGCGGCCTGACCCGCGCG
CAGGCCGATATCAAGCGCGTGACGATGGGCCCCCTGGTGGACGCCTTCACGCTCGACCCCACCCTGCCGCCGCTGGATGC
CGCGCAGCAGAAGCTGGTGCTGGGCGGCGAGGCCCCGCTGTGGAGCGAACTGGTCACGGACGAAACGCTGATGCGCGCCT
GTGTGCCGCGCGCCGCCGCCATAGCCGAGCGGTTCTGGTCGCAGCCGGAGATCCGCGATGTCGATGGCATGGATCGCCGC
CTGACGGAGGTGGCGAGCCGCCTGGAGGTGACCGGCCTGCAGGCGCGGGCGAACGCCTATCGGATGCAGGCCCGCCTGGC
GCCCGCCGATCCCGGGGCGGTCGCCTGCCTGATGGGTGCCGTGATGCCGGTGCGCAATTACGCCCTGAACAGCTTCGTCC
GGCGCAGCGGCCAGGTGCGGTTCGACGAACTGGCGGAAATCGCATCCCCCGACCCCATCGCCGCGATGCGGTTCAACGCG
CTGGCCGCGCGCTTCGCCGCCGGGGATCGCGGCGTGGCGGAGGCGTTGCGGGCGCAACTCGGCGCGTGGGCCGCGTGCGG
GGATCGCTTCGCCACGGTCGCGCAGGGCGTGGGCGCGCTGGAACAGGGCCTGCCGGTGGCGCGGGACATCGCGGCCCTGG
CCCGCATCGGGCTGGCCGCCCTGTCCGGCCCCCTGGACGACGCGCAGCGCCGCGATGCCGTGGCACGGATCGCAGCCGAC
CAGGCGGTGGTCGAGTCGTTTGCCGGCGTGGTGCGGACCCACGGCGTGAAACCGCCGCCCGCCGGGCTGCTGGTGGCGAT
CCTGCCCGGGATCAGGTCCCTGATGGGGTAG

Upstream 100 bases:

>100_bases
GGGCCGGTGGCGGCATGGCGGGCGGCGTGGCGGCCGCGGCGCTGGGCGCGGTGCTGGCCGTGGCGCTGCCGGCGGGGCAC
GCGCGGGCGGCACCGGCGTG

Downstream 100 bases:

>100_bases
CAGCGGCCCCTGGTCTGCCCTATCGCGCGGCGTCGCGCGCGCGGGCGAACCAGGGCGTCATGCGTCGCAATGCCTCCTCC
AGCCGGTCGGTCGAGACCGC

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MPLPASAHYSGQTLSLANGLAVQWDHAPTPLLRRAADRLRARLDRLAGRVLPADDHASGAAMLRVRYGADPSFLALGEKE
QYRLAVRPDGITLDAAGPAGVLDGFATLAQLAAQGPQGPVLMQADIDDRPRFPWRGIMIDVSRHFMRIETLHRQIDAMEQ
VKLNVLHLHLGDSQGFRVESRLFPGLQRQGSHGQFYTQAQIRDLVAYAADRGVRIVPEFDTPGHALAILLAYPALAAQPV
DPAMPDPDDAALNPTLDATLHFVTQLYGEMGRLFSDRYFHAGGDEVQAEQWTRNPKITAFMKAHGFADTASLQAAFTARV
QSVLARQGKIMVGWDEVSAAPIPKSVVVEAWRSSKFIGTATRAGHPVVVSAGYYLDLLNPAEQHYRVDPLDVQASGLTRA
QADIKRVTMGPLVDAFTLDPTLPPLDAAQQKLVLGGEAPLWSELVTDETLMRACVPRAAAIAERFWSQPEIRDVDGMDRR
LTEVASRLEVTGLQARANAYRMQARLAPADPGAVACLMGAVMPVRNYALNSFVRRSGQVRFDELAEIASPDPIAAMRFNA
LAARFAAGDRGVAEALRAQLGAWAACGDRFATVAQGVGALEQGLPVARDIAALARIGLAALSGPLDDAQRRDAVARIAAD
QAVVESFAGVVRTHGVKPPPAGLLVAILPGIRSLMG

Sequences:

>Translated_676_residues
MPLPASAHYSGQTLSLANGLAVQWDHAPTPLLRRAADRLRARLDRLAGRVLPADDHASGAAMLRVRYGADPSFLALGEKE
QYRLAVRPDGITLDAAGPAGVLDGFATLAQLAAQGPQGPVLMQADIDDRPRFPWRGIMIDVSRHFMRIETLHRQIDAMEQ
VKLNVLHLHLGDSQGFRVESRLFPGLQRQGSHGQFYTQAQIRDLVAYAADRGVRIVPEFDTPGHALAILLAYPALAAQPV
DPAMPDPDDAALNPTLDATLHFVTQLYGEMGRLFSDRYFHAGGDEVQAEQWTRNPKITAFMKAHGFADTASLQAAFTARV
QSVLARQGKIMVGWDEVSAAPIPKSVVVEAWRSSKFIGTATRAGHPVVVSAGYYLDLLNPAEQHYRVDPLDVQASGLTRA
QADIKRVTMGPLVDAFTLDPTLPPLDAAQQKLVLGGEAPLWSELVTDETLMRACVPRAAAIAERFWSQPEIRDVDGMDRR
LTEVASRLEVTGLQARANAYRMQARLAPADPGAVACLMGAVMPVRNYALNSFVRRSGQVRFDELAEIASPDPIAAMRFNA
LAARFAAGDRGVAEALRAQLGAWAACGDRFATVAQGVGALEQGLPVARDIAALARIGLAALSGPLDDAQRRDAVARIAAD
QAVVESFAGVVRTHGVKPPPAGLLVAILPGIRSLMG
>Mature_675_residues
PLPASAHYSGQTLSLANGLAVQWDHAPTPLLRRAADRLRARLDRLAGRVLPADDHASGAAMLRVRYGADPSFLALGEKEQ
YRLAVRPDGITLDAAGPAGVLDGFATLAQLAAQGPQGPVLMQADIDDRPRFPWRGIMIDVSRHFMRIETLHRQIDAMEQV
KLNVLHLHLGDSQGFRVESRLFPGLQRQGSHGQFYTQAQIRDLVAYAADRGVRIVPEFDTPGHALAILLAYPALAAQPVD
PAMPDPDDAALNPTLDATLHFVTQLYGEMGRLFSDRYFHAGGDEVQAEQWTRNPKITAFMKAHGFADTASLQAAFTARVQ
SVLARQGKIMVGWDEVSAAPIPKSVVVEAWRSSKFIGTATRAGHPVVVSAGYYLDLLNPAEQHYRVDPLDVQASGLTRAQ
ADIKRVTMGPLVDAFTLDPTLPPLDAAQQKLVLGGEAPLWSELVTDETLMRACVPRAAAIAERFWSQPEIRDVDGMDRRL
TEVASRLEVTGLQARANAYRMQARLAPADPGAVACLMGAVMPVRNYALNSFVRRSGQVRFDELAEIASPDPIAAMRFNAL
AARFAAGDRGVAEALRAQLGAWAACGDRFATVAQGVGALEQGLPVARDIAALARIGLAALSGPLDDAQRRDAVARIAADQ
AVVESFAGVVRTHGVKPPPAGLLVAILPGIRSLMG

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=443, Percent_Identity=33.6343115124154, Blast_Score=245, Evalue=1e-64,
Organism=Homo sapiens, GI189181666, Length=436, Percent_Identity=31.1926605504587, Blast_Score=226, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17569815, Length=445, Percent_Identity=30.7865168539326, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24657468, Length=429, Percent_Identity=27.2727272727273, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17647501, Length=429, Percent_Identity=27.2727272727273, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281365639, Length=429, Percent_Identity=27.5058275058275, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24657474, Length=429, Percent_Identity=27.5058275058275, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45551090, Length=486, Percent_Identity=28.6008230452675, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24653074, Length=481, Percent_Identity=28.6902286902287, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17933586, Length=447, Percent_Identity=28.6353467561521, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 72742; Mature: 72611

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPASAHYSGQTLSLANGLAVQWDHAPTPLLRRAADRLRARLDRLAGRVLPADDHASGA
CCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
AMLRVRYGADPSFLALGEKEQYRLAVRPDGITLDAAGPAGVLDGFATLAQLAAQGPQGPV
EEEEEEECCCCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCE
LMQADIDDRPRFPWRGIMIDVSRHFMRIETLHRQIDAMEQVKLNVLHLHLGDSQGFRVES
EEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEHH
RLFPGLQRQGSHGQFYTQAQIRDLVAYAADRGVRIVPEFDTPGHALAILLAYPALAAQPV
HHCCCHHCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
DPAMPDPDDAALNPTLDATLHFVTQLYGEMGRLFSDRYFHAGGDEVQAEQWTRNPKITAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCEEEE
MKAHGFADTASLQAAFTARVQSVLARQGKIMVGWDEVSAAPIPKSVVVEAWRSSKFIGTA
EECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEC
TRAGHPVVVSAGYYLDLLNPAEQHYRVDPLDVQASGLTRAQADIKRVTMGPLVDAFTLDP
CCCCCCEEEECCCEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHEECCC
TLPPLDAAQQKLVLGGEAPLWSELVTDETLMRACVPRAAAIAERFWSQPEIRDVDGMDRR
CCCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LTEVASRLEVTGLQARANAYRMQARLAPADPGAVACLMGAVMPVRNYALNSFVRRSGQVR
HHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDELAEIASPDPIAAMRFNALAARFAAGDRGVAEALRAQLGAWAACGDRFATVAQGVGAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EQGLPVARDIAALARIGLAALSGPLDDAQRRDAVARIAADQAVVESFAGVVRTHGVKPPP
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGLLVAILPGIRSLMG
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLPASAHYSGQTLSLANGLAVQWDHAPTPLLRRAADRLRARLDRLAGRVLPADDHASGA
CCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
AMLRVRYGADPSFLALGEKEQYRLAVRPDGITLDAAGPAGVLDGFATLAQLAAQGPQGPV
EEEEEEECCCCCEEEECCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCE
LMQADIDDRPRFPWRGIMIDVSRHFMRIETLHRQIDAMEQVKLNVLHLHLGDSQGFRVES
EEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEHH
RLFPGLQRQGSHGQFYTQAQIRDLVAYAADRGVRIVPEFDTPGHALAILLAYPALAAQPV
HHCCCHHCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
DPAMPDPDDAALNPTLDATLHFVTQLYGEMGRLFSDRYFHAGGDEVQAEQWTRNPKITAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCEEEE
MKAHGFADTASLQAAFTARVQSVLARQGKIMVGWDEVSAAPIPKSVVVEAWRSSKFIGTA
EECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEC
TRAGHPVVVSAGYYLDLLNPAEQHYRVDPLDVQASGLTRAQADIKRVTMGPLVDAFTLDP
CCCCCCEEEECCCEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHEECCC
TLPPLDAAQQKLVLGGEAPLWSELVTDETLMRACVPRAAAIAERFWSQPEIRDVDGMDRR
CCCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LTEVASRLEVTGLQARANAYRMQARLAPADPGAVACLMGAVMPVRNYALNSFVRRSGQVR
HHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDELAEIASPDPIAAMRFNALAARFAAGDRGVAEALRAQLGAWAACGDRFATVAQGVGAL
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EQGLPVARDIAALARIGLAALSGPLDDAQRRDAVARIAADQAVVESFAGVVRTHGVKPPP
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGLLVAILPGIRSLMG
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]