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The map label for this gene is mtnD

Identifier: 162146411

GI number: 162146411

Start: 590464

End: 591003

Strand: Direct

Name: mtnD

Synonym: GDI_0586

Alternate gene names: 162146411

Gene position: 590464-591003 (Clockwise)

Preceding gene: 162146410

Following gene: 162146412

Centisome position: 14.97

GC content: 67.96

Gene sequence:

>540_bases
ATGAGCCACCTGACCGTCTATCGCGACGACGACCCGGACGACATCGTCCTGCGGACCGACGACGCGGCCGTCATCGCCGA
CGCGTTGCGCGGCATCGGTGCGCGCTTCGAACGCTGGGACAGCCCCGTGGTGCCCCCGCTCGACGCCACGCCCGACGCGG
TGCTGAACACCTACCGCCCCTATCTGGACGAGCTGATGGGTGAGACCGGGGCAGGGTCCGCCGACGTGGTGCGCATCAAC
GCCGCCACCCCCAACCTGACGGCCCTGCGCGACAAGTTCCTCTCCGAACATACGCATAGCGAGGACGAGGTCCGGTTCTT
CGTCCATGGCAGCGGCAATTTCGTGCTGCATGTCGACGGCCGGGTCTATGACGTGTGCTGCACGGCCGGCGACCTGATCT
CGGTCCCCCGGGGGACGCCCCACTGGTTCGATGCCGGGCTGTCTCCCGACGTGGTGGCGCTGCGCGTGTTCACCGACACG
ACCGGCTGGATCGCGGATTATACGGGCGACGACATCGCCCGGCGCTTTCCCGTTAGCTGA

Upstream 100 bases:

>100_bases
GCGTGTATGTCTGGGGCGGGACGATGGACGTTGCCCTCGCCCGGCTCGAGGGCCTGGAATTCCTGCTGGCCTGCGAACTG
GAAAGAAGGAAGGTCGCACG

Downstream 100 bases:

>100_bases
GGGGCTGGCGGATATGGTGGTGACGGCGTCCACGGACGCTATCGACTCGGTCCTGCTGGATATCGAAGGTACGACGATTC
CCGTCGCCTTCGTGCACCAG

Product: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRPYLDELMGETGAGSADVVRIN
AATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDGRVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDT
TGWIADYTGDDIARRFPVS

Sequences:

>Translated_179_residues
MSHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRPYLDELMGETGAGSADVVRIN
AATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDGRVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDT
TGWIADYTGDDIARRFPVS
>Mature_178_residues
SHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRPYLDELMGETGAGSADVVRINA
ATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDGRVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDTT
GWIADYTGDDIARRFPVS

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTND_GLUDA (A9H8G4)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001600870.1
- RefSeq:   YP_002275809.1
- ProteinModelPortal:   A9H8G4
- SMR:   A9H8G4
- GeneID:   5792094
- GeneID:   6974822
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1414
- HOGENOM:   HBG660685
- OMA:   CEKNDLI
- ProtClustDB:   CLSK936308
- HAMAP:   MF_01682
- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR23418

Pfam domain/function: PF03079 ARD; SSF51182 RmlC_like_cupin

EC number: =1.13.11.54; =1.13.11.53

Molecular weight: Translated: 19647; Mature: 19516

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRP
CCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
YLDELMGETGAGSADVVRINAATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDG
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECC
RVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDTTGWIADYTGDDIARRFPVS
EEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCHHHHCCCCC
>Mature Secondary Structure 
SHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRP
CCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
YLDELMGETGAGSADVVRINAATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDG
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECC
RVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDTTGWIADYTGDDIARRFPVS
EEEEEEECCCCEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA