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The map label for this gene is mtnC [H]

Identifier: 162146412

GI number: 162146412

Start: 591017

End: 591730

Strand: Direct

Name: mtnC [H]

Synonym: GDI_0587

Alternate gene names: 162146412

Gene position: 591017-591730 (Clockwise)

Preceding gene: 162146411

Following gene: 162146413

Centisome position: 14.98

GC content: 71.01

Gene sequence:

>714_bases
ATGGTGGTGACGGCGTCCACGGACGCTATCGACTCGGTCCTGCTGGATATCGAAGGTACGACGATTCCCGTCGCCTTCGT
GCACCAGGTGCTGTTTCCCTACGCCCGCGCGGCGATGCCCGGCCTGCTGGCCCAACGGGCGGACGATCCGGCGGTGCGCG
CGGCCGTGGCCGATATCGCGGCGCTGGCCCCCGGCGTGCCCCCGCTGGACCAGTTGAACGCCTGGATGGACCGGGACGAG
AAGATCGGACCGCTCAAGGCCCTGCAGGGCCTGGCTTGGGAAGAGGGGTATCGCACCGGCGCCCTGCGCGCGACGCTCTA
CCCGGACGTGGTGCCGGCACTGCGGCGCTGGCGGGCAGCGGGGCTGCGGCTCGCGGTCTATTCCTCGGGCTCCGAGGCCG
CGCAGCGCCTGATCTACGGCCACACCACCGACGGCGACGTCGCCGGACTGTTTAGTGGTTTTTATGACCTGCGCATCGGT
GGCAAGCGCGCGGCCGGCAGCTATCGCGCCATCCTGGCTGAAACCGGCTGGGCCGCCGGGCGCACGCTGTTCCTGTCCGA
CATCACGGCCGAACTGGATGCGGCGGAGGAAGCCGGCCTGCGCACCTGCCAGCTCGTCCGGCCGGAAGACGGCACCGTGG
CTGGCGACCGCCATCCCGTCGCCACGACGCTGGACGACGTGGCACGCCGCTTCGCCCTGCCGGTTGCCGCATGA

Upstream 100 bases:

>100_bases
GTGGCGCTGCGCGTGTTCACCGACACGACCGGCTGGATCGCGGATTATACGGGCGACGACATCGCCCGGCGCTTTCCCGT
TAGCTGAGGGGCTGGCGGAT

Downstream 100 bases:

>100_bases
GGGCGCACCTGCATACCGGCTGGCGCCATATCCCGGCCGAGGCGCGGGGCATGGCGGCGGCGCTGGGCAATTTCGACGGC
GTGCATCTGGGCCATGCCCA

Product: enolase-phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVVTASTDAIDSVLLDIEGTTIPVAFVHQVLFPYARAAMPGLLAQRADDPAVRAAVADIAALAPGVPPLDQLNAWMDRDE
KIGPLKALQGLAWEEGYRTGALRATLYPDVVPALRRWRAAGLRLAVYSSGSEAAQRLIYGHTTDGDVAGLFSGFYDLRIG
GKRAAGSYRAILAETGWAAGRTLFLSDITAELDAAEEAGLRTCQLVRPEDGTVAGDRHPVATTLDDVARRFALPVAA

Sequences:

>Translated_237_residues
MVVTASTDAIDSVLLDIEGTTIPVAFVHQVLFPYARAAMPGLLAQRADDPAVRAAVADIAALAPGVPPLDQLNAWMDRDE
KIGPLKALQGLAWEEGYRTGALRATLYPDVVPALRRWRAAGLRLAVYSSGSEAAQRLIYGHTTDGDVAGLFSGFYDLRIG
GKRAAGSYRAILAETGWAAGRTLFLSDITAELDAAEEAGLRTCQLVRPEDGTVAGDRHPVATTLDDVARRFALPVAA
>Mature_237_residues
MVVTASTDAIDSVLLDIEGTTIPVAFVHQVLFPYARAAMPGLLAQRADDPAVRAAVADIAALAPGVPPLDQLNAWMDRDE
KIGPLKALQGLAWEEGYRTGALRATLYPDVVPALRRWRAAGLRLAVYSSGSEAAQRLIYGHTTDGDVAGLFSGFYDLRIG
GKRAAGSYRAILAETGWAAGRTLFLSDITAELDAAEEAGLRTCQLVRPEDGTVAGDRHPVATTLDDVARRFALPVAA

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=242, Percent_Identity=37.603305785124, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115533232, Length=225, Percent_Identity=35.1111111111111, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6320797, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281360080, Length=231, Percent_Identity=38.5281385281385, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24644163, Length=231, Percent_Identity=38.5281385281385, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25154; Mature: 25154

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVTASTDAIDSVLLDIEGTTIPVAFVHQVLFPYARAAMPGLLAQRADDPAVRAAVADIA
CEEECCHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALAPGVPPLDQLNAWMDRDEKIGPLKALQGLAWEEGYRTGALRATLYPDVVPALRRWRAA
HHCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCCCCEEEECCHHHHHHHHHHHHC
GLRLAVYSSGSEAAQRLIYGHTTDGDVAGLFSGFYDLRIGGKRAAGSYRAILAETGWAAG
CEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCCC
RTLFLSDITAELDAAEEAGLRTCQLVRPEDGTVAGDRHPVATTLDDVARRFALPVAA
CEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVVTASTDAIDSVLLDIEGTTIPVAFVHQVLFPYARAAMPGLLAQRADDPAVRAAVADIA
CEEECCHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALAPGVPPLDQLNAWMDRDEKIGPLKALQGLAWEEGYRTGALRATLYPDVVPALRRWRAA
HHCCCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCCCCEEEECCHHHHHHHHHHHHC
GLRLAVYSSGSEAAQRLIYGHTTDGDVAGLFSGFYDLRIGGKRAAGSYRAILAETGWAAG
CEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCCC
RTLFLSDITAELDAAEEAGLRTCQLVRPEDGTVAGDRHPVATTLDDVARRFALPVAA
CEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA