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The map label for this gene is yfkJ [H]

Identifier: 162146398

GI number: 162146398

Start: 582023

End: 582496

Strand: Direct

Name: yfkJ [H]

Synonym: GDI_0573

Alternate gene names: 162146398

Gene position: 582023-582496 (Clockwise)

Preceding gene: 162146397

Following gene: 162146399

Centisome position: 14.76

GC content: 69.83

Gene sequence:

>474_bases
ATGTCCCGCCGTCCCGCCATCCTGTTCGTCTGCACCGGGAATATCTGCCGCTCCCCCCTGGCCGAGGCCGCGTTTCGCGC
CGCCGCCACCCGATGCGGGCTGGATGCCGTCGTCGATTCGGCGGGGACCGGCGACTGGCATACCGGCGAGCCGCCGGATC
GCCGCGCGCAGGAGGTGGCCCGCCGCAACGGGATCGATATCGCGGGCTATCGCGCGCGCATGGTCACGGCGGAGGATTTC
CGAGTCTTCACCCATATCGTCGCCCTGGACCACACCCACCTGAAGGTCCTGCGCGCGCGCCGGCCGAGCGATGGAATCGC
GGAGCTTTCGCTGCTGCTGGATCATGTGGCAGGGCGTGTCGGCCAGTCGGTGGCCGATCCCTATTACGGACAGGCGCGGG
ATTTCCACACCACCTGGGCGGACGTCCAGGCGGGGACCGAGGCCCTGGTGGCGAGGCTCATCCGCTCCCGTTAG

Upstream 100 bases:

>100_bases
ACGGTGCGCGCGCTGGATATCGGGCTGGATTACGAGGAAGGGTAACCGGATCAAAGTTTTTTGGTTCTTTTTTTCAAAAA
GGAACCGCTAGAGTCGTGCC

Downstream 100 bases:

>100_bases
GAGGATACGCCGCACATGCCGTTCCGCCGGACCATGTCGATGCTTGTCCTTCTCGGGGCGATGCTGGCCGCCGCCGGGAC
ACGGGCCGCGCCGCCGGTCG

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSRRPAILFVCTGNICRSPLAEAAFRAAATRCGLDAVVDSAGTGDWHTGEPPDRRAQEVARRNGIDIAGYRARMVTAEDF
RVFTHIVALDHTHLKVLRARRPSDGIAELSLLLDHVAGRVGQSVADPYYGQARDFHTTWADVQAGTEALVARLIRSR

Sequences:

>Translated_157_residues
MSRRPAILFVCTGNICRSPLAEAAFRAAATRCGLDAVVDSAGTGDWHTGEPPDRRAQEVARRNGIDIAGYRARMVTAEDF
RVFTHIVALDHTHLKVLRARRPSDGIAELSLLLDHVAGRVGQSVADPYYGQARDFHTTWADVQAGTEALVARLIRSR
>Mature_156_residues
SRRPAILFVCTGNICRSPLAEAAFRAAATRCGLDAVVDSAGTGDWHTGEPPDRRAQEVARRNGIDIAGYRARMVTAEDFR
VFTHIVALDHTHLKVLRARRPSDGIAELSLLLDHVAGRVGQSVADPYYGQARDFHTTWADVQAGTEALVARLIRSR

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=139, Percent_Identity=38.1294964028777, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI4757714, Length=139, Percent_Identity=38.1294964028777, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI96304457, Length=79, Percent_Identity=44.3037974683544, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=26.6233766233766, Blast_Score=95, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78706770, Length=130, Percent_Identity=40.7692307692308, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706772, Length=130, Percent_Identity=40.7692307692308, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78711846, Length=130, Percent_Identity=33.8461538461538, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78706766, Length=135, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI78706768, Length=135, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI78706764, Length=124, Percent_Identity=33.8709677419355, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648069, Length=91, Percent_Identity=38.4615384615385, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17192; Mature: 17060

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRPAILFVCTGNICRSPLAEAAFRAAATRCGLDAVVDSAGTGDWHTGEPPDRRAQEVA
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHH
RRNGIDIAGYRARMVTAEDFRVFTHIVALDHTHLKVLRARRPSDGIAELSLLLDHVAGRV
HHCCCCCCCCCEEEECHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GQSVADPYYGQARDFHTTWADVQAGTEALVARLIRSR
HHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SRRPAILFVCTGNICRSPLAEAAFRAAATRCGLDAVVDSAGTGDWHTGEPPDRRAQEVA
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHH
RRNGIDIAGYRARMVTAEDFRVFTHIVALDHTHLKVLRARRPSDGIAELSLLLDHVAGRV
HHCCCCCCCCCEEEECHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GQSVADPYYGQARDFHTTWADVQAGTEALVARLIRSR
HHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]