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The map label for this gene is ybdL [H]

Identifier: 162146352

GI number: 162146352

Start: 521916

End: 523088

Strand: Direct

Name: ybdL [H]

Synonym: GDI_0527

Alternate gene names: 162146352

Gene position: 521916-523088 (Clockwise)

Preceding gene: 162146349

Following gene: 162146355

Centisome position: 13.23

GC content: 67.77

Gene sequence:

>1173_bases
ATGTTCATGAAATCGCTGAACAGCATGCTGTCCGGCCTGCCGACGACGATCTTCACCGTCATGTCGGCGCTGGCGGCGCG
GCATGACGCCATCAATCTGGGCCAGGGCTTCCCGGACACCGAAGGACCGGCCGATCTGATCGAAGCCGCGGCGGCGGCCC
TGCGCGACGGCCGCAACCAGTATCCGCCCCTGACCGGGGTCCCGGAACTGCGGACGGCGGTCGCGCGGTCGAACGCGCGA
TTCTATGGCCTGTCGGTCGATCCGGCGACCGAGGTGATCGTGACCTCCGGCGCGACCGAGGCCCTGGCGGCCTCGCTGAT
GGCGATGGTCGATCCGGGGGATGAGGTCGTGGTGCTGGAACCGCTCTATGACACCTACCTGCCGGTGATCCGCGCGCTGG
GTGCCGTGGCGCGGCCGGTGCGCCTGACACCGCCGGACTGGTCCCTGCCGCGTGCCGAACTGGCGGCGGCTTTCGGGCCC
AGGACCAAGGCAATCATGCTCAATTCCCCGATGAACCCGACGGGCAAGGTCTTCGGCCCGGACGAACTGGCCTTCATCGC
CGACCTGGTGGCGCGCCACCAGGTCTATGCGATCTGTGACGAGGTGTACGAGCACCTGACATTCGGCGGTGCGCGCCATA
TCCCGCTGATGACCCTGCCGGGCATGCGCCCGCGTTGCGTGCGCATCGGCAGCGCGGGCAAGAGCTTCTCGCTGACCGGA
TGGAAGGTCGGCTATGTCACCGCGCCGGCCGCCATCGCCGCGACCGTCGCCAAGGCGCACCAGCTTCTGACCTTCACCAC
GCCGCCGAACCTGCAGCGCGCGGTCGCGGTGGGGCTGGACAAGGATACGGATTATTTCACCACCCTTGCCGCCGACATGC
AGGCCAAGCGCGACTTGTTGTCCGACGGGCTGCGCGCCGCCGGCTTCGACGTGCTGCCGTGCGACGGCAGCTATTTCATC
GTGGCGGATATCCGCTCGACCGGTTTCGCGGGGGACGACGTGGCGTTCTGCCGTGCCCTGACCGAACGGTGCCGGGTCAC
GGCGATTCCGGTCTCGGCCTTCTATGGTACCGACAACGCACCGGACCATCTGGTGCGATTCGCCTTCTGCAAGAAGGACC
CGATCCTGGCCGAAGCCGTGGCCCGGATTCGGGCCGGCGTGCGCGATTTGTAG

Upstream 100 bases:

>100_bases
ATTGCAAAAGGCCGGCATTTTACGCACATCTGCGCATGGCCGGCGGATTGCAGCACGGATCGCAGCAGGGAAGGGCCCAC
AGGACGGGTCCGAAGGAAGG

Downstream 100 bases:

>100_bases
GAACGCCGGGCAAGGCCGGGCTCTTTTTCACCCTGTGGGTGATTGACGTGCCGGACGAGCTTCTCTAAATCACAGCCCGC
TGTGGCGGACGTAGCTCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MFMKSLNSMLSGLPTTIFTVMSALAARHDAINLGQGFPDTEGPADLIEAAAAALRDGRNQYPPLTGVPELRTAVARSNAR
FYGLSVDPATEVIVTSGATEALAASLMAMVDPGDEVVVLEPLYDTYLPVIRALGAVARPVRLTPPDWSLPRAELAAAFGP
RTKAIMLNSPMNPTGKVFGPDELAFIADLVARHQVYAICDEVYEHLTFGGARHIPLMTLPGMRPRCVRIGSAGKSFSLTG
WKVGYVTAPAAIAATVAKAHQLLTFTTPPNLQRAVAVGLDKDTDYFTTLAADMQAKRDLLSDGLRAAGFDVLPCDGSYFI
VADIRSTGFAGDDVAFCRALTERCRVTAIPVSAFYGTDNAPDHLVRFAFCKKDPILAEAVARIRAGVRDL

Sequences:

>Translated_390_residues
MFMKSLNSMLSGLPTTIFTVMSALAARHDAINLGQGFPDTEGPADLIEAAAAALRDGRNQYPPLTGVPELRTAVARSNAR
FYGLSVDPATEVIVTSGATEALAASLMAMVDPGDEVVVLEPLYDTYLPVIRALGAVARPVRLTPPDWSLPRAELAAAFGP
RTKAIMLNSPMNPTGKVFGPDELAFIADLVARHQVYAICDEVYEHLTFGGARHIPLMTLPGMRPRCVRIGSAGKSFSLTG
WKVGYVTAPAAIAATVAKAHQLLTFTTPPNLQRAVAVGLDKDTDYFTTLAADMQAKRDLLSDGLRAAGFDVLPCDGSYFI
VADIRSTGFAGDDVAFCRALTERCRVTAIPVSAFYGTDNAPDHLVRFAFCKKDPILAEAVARIRAGVRDL
>Mature_390_residues
MFMKSLNSMLSGLPTTIFTVMSALAARHDAINLGQGFPDTEGPADLIEAAAAALRDGRNQYPPLTGVPELRTAVARSNAR
FYGLSVDPATEVIVTSGATEALAASLMAMVDPGDEVVVLEPLYDTYLPVIRALGAVARPVRLTPPDWSLPRAELAAAFGP
RTKAIMLNSPMNPTGKVFGPDELAFIADLVARHQVYAICDEVYEHLTFGGARHIPLMTLPGMRPRCVRIGSAGKSFSLTG
WKVGYVTAPAAIAATVAKAHQLLTFTTPPNLQRAVAVGLDKDTDYFTTLAADMQAKRDLLSDGLRAAGFDVLPCDGSYFI
VADIRSTGFAGDDVAFCRALTERCRVTAIPVSAFYGTDNAPDHLVRFAFCKKDPILAEAVARIRAGVRDL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=404, Percent_Identity=35.6435643564356, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI56713256, Length=404, Percent_Identity=35.6435643564356, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI95147551, Length=413, Percent_Identity=35.1089588377724, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI169881279, Length=413, Percent_Identity=35.1089588377724, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI169881281, Length=411, Percent_Identity=30.1703163017032, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4507369, Length=224, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=41.7989417989418, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=28.8659793814433, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787710, Length=237, Percent_Identity=29.957805907173, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787909, Length=315, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788627, Length=160, Percent_Identity=23.125, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=33.8422391857506, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=33.8422391857506, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=30.3258145363409, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=346, Percent_Identity=25.1445086705202, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=31.9480519480519, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28573069, Length=400, Percent_Identity=35, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24646114, Length=400, Percent_Identity=35, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI28573067, Length=400, Percent_Identity=35, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI28573065, Length=400, Percent_Identity=35, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI18859735, Length=212, Percent_Identity=28.7735849056604, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 41641; Mature: 41641

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMKSLNSMLSGLPTTIFTVMSALAARHDAINLGQGFPDTEGPADLIEAAAAALRDGRNQ
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
YPPLTGVPELRTAVARSNARFYGLSVDPATEVIVTSGATEALAASLMAMVDPGDEVVVLE
CCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEC
PLYDTYLPVIRALGAVARPVRLTPPDWSLPRAELAAAFGPRTKAIMLNSPMNPTGKVFGP
CHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
DELAFIADLVARHQVYAICDEVYEHLTFGGARHIPLMTLPGMRPRCVRIGSAGKSFSLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCCCCEECCC
WKVGYVTAPAAIAATVAKAHQLLTFTTPPNLQRAVAVGLDKDTDYFTTLAADMQAKRDLL
EEEEEEECHHHHHHHHHHHHHEEEECCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHH
SDGLRAAGFDVLPCDGSYFIVADIRSTGFAGDDVAFCRALTERCRVTAIPVSAFYGTDNA
HCCHHHCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCEEEEEEEEEECCCCCC
PDHLVRFAFCKKDPILAEAVARIRAGVRDL
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFMKSLNSMLSGLPTTIFTVMSALAARHDAINLGQGFPDTEGPADLIEAAAAALRDGRNQ
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
YPPLTGVPELRTAVARSNARFYGLSVDPATEVIVTSGATEALAASLMAMVDPGDEVVVLE
CCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEC
PLYDTYLPVIRALGAVARPVRLTPPDWSLPRAELAAAFGPRTKAIMLNSPMNPTGKVFGP
CHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
DELAFIADLVARHQVYAICDEVYEHLTFGGARHIPLMTLPGMRPRCVRIGSAGKSFSLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCCCCEECCC
WKVGYVTAPAAIAATVAKAHQLLTFTTPPNLQRAVAVGLDKDTDYFTTLAADMQAKRDLL
EEEEEEECHHHHHHHHHHHHHEEEECCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHH
SDGLRAAGFDVLPCDGSYFIVADIRSTGFAGDDVAFCRALTERCRVTAIPVSAFYGTDNA
HCCHHHCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCEEEEEEEEEECCCCCC
PDHLVRFAFCKKDPILAEAVARIRAGVRDL
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]