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The map label for this gene is yajO [H]

Identifier: 162146282

GI number: 162146282

Start: 453534

End: 454514

Strand: Direct

Name: yajO [H]

Synonym: GDI_0457

Alternate gene names: 162146282

Gene position: 453534-454514 (Clockwise)

Preceding gene: 162146281

Following gene: 162146284

Centisome position: 11.5

GC content: 66.36

Gene sequence:

>981_bases
ATGGAGTACACGCGCTTGGGCCGGACCGGCCTGCAGGTATCGCGTATCTGCCTGGGCTGCATGACCTATGGCGTGCCGGA
ACGCGGCAACCATCCCTGGACGCTGGACGAGGAAACCAGCCGCCCGCTGATCCGTCAGGCGCTGGACGCCGGGATCAATT
TTCTCGATACCGCCAATACCTATTCCGACGGCACGTCGGAGGAGATCGTCGGCCGCGCGATCCGCGATTTCGCCCGGCGC
GAGGAGATCGTGCTGGCCACCAAGGTGTTCTTTCCGCAGCGCAAGGGCCCCAACGGGGGCGGTCTGTCGCGCAAGGCGAT
CCTGGGCGAGATCGACAACAGCCTGCGCCGCCTCGGTACCGATTACGTGGACCTCTACCAGATCCATCGCTGGGACCCTG
AAACGCCGATCGAGGAAACGATGGAGGCGTTGCATGACGTCGTGAAGGCGGGCAAGGCGCGCTATATCGGCGCGTCGTCC
ATGTATGCGTGGCAGTTCGCCAAGGCGGTCTACACGTCGCGGCTCAACGGCTGGACGGAGTTCGTCAGCATGCAGGACCA
TCTGAACCTGCTGAACCGCGAGGAAGAGCGCGAAATGCTGCCCTTCTGCCGGGACCAGGGGATCGGCGTCCTGCCCTGGA
GCCCGCTGGCGCGCGGGCGCCTGGCGCGGGACGGGAACGAAAGCACCAGCCGGCAGGAAACGGACAACTACGCCAAAATC
CTGTATGAAAAAACGGAAGAATCGGATCGCGCCGTCATTGATGCCGTCGGCCGGATCGCGGCGCAACGCGGCGTGCCGCG
CGCCCAGGTCGCGCTGGCGTGGGTGCTCCAGACGCCGGGCGTGACGGCGCCGATCGTGGGGGCGTCGAAGCCCGGGCAAC
TGGCCGACGCGGTCGGTGCGCTGTCCCTGACCCTGACGGCGGAGGAGATCGCCGCCCTGGCAGCACCCTATGTTCCGCAC
CCGGTCGTGGGATTCGGCTAA

Upstream 100 bases:

>100_bases
CGGGTCGCAGTGCGATGCTTGATGAGGCGCGCGTCCGTGACTACGTGATTTCCCATGCCGGTTCTGTGCCGGTCCTGGAA
ACAGTCGGGGAAGACGCATC

Downstream 100 bases:

>100_bases
GTCCTCCTTCAAAAAGATCCTCTAGAATTCAGCAACCTTCCCCCAGGACGAAACCCTGAAGCGCTCGGGGCTGTACGGCA
CGGGATCGACGATCGGGGCC

Product: oxidoreductase (aldo/keto reductase) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEYTRLGRTGLQVSRICLGCMTYGVPERGNHPWTLDEETSRPLIRQALDAGINFLDTANTYSDGTSEEIVGRAIRDFARR
EEIVLATKVFFPQRKGPNGGGLSRKAILGEIDNSLRRLGTDYVDLYQIHRWDPETPIEETMEALHDVVKAGKARYIGASS
MYAWQFAKAVYTSRLNGWTEFVSMQDHLNLLNREEEREMLPFCRDQGIGVLPWSPLARGRLARDGNESTSRQETDNYAKI
LYEKTEESDRAVIDAVGRIAAQRGVPRAQVALAWVLQTPGVTAPIVGASKPGQLADAVGALSLTLTAEEIAALAAPYVPH
PVVGFG

Sequences:

>Translated_326_residues
MEYTRLGRTGLQVSRICLGCMTYGVPERGNHPWTLDEETSRPLIRQALDAGINFLDTANTYSDGTSEEIVGRAIRDFARR
EEIVLATKVFFPQRKGPNGGGLSRKAILGEIDNSLRRLGTDYVDLYQIHRWDPETPIEETMEALHDVVKAGKARYIGASS
MYAWQFAKAVYTSRLNGWTEFVSMQDHLNLLNREEEREMLPFCRDQGIGVLPWSPLARGRLARDGNESTSRQETDNYAKI
LYEKTEESDRAVIDAVGRIAAQRGVPRAQVALAWVLQTPGVTAPIVGASKPGQLADAVGALSLTLTAEEIAALAAPYVPH
PVVGFG
>Mature_326_residues
MEYTRLGRTGLQVSRICLGCMTYGVPERGNHPWTLDEETSRPLIRQALDAGINFLDTANTYSDGTSEEIVGRAIRDFARR
EEIVLATKVFFPQRKGPNGGGLSRKAILGEIDNSLRRLGTDYVDLYQIHRWDPETPIEETMEALHDVVKAGKARYIGASS
MYAWQFAKAVYTSRLNGWTEFVSMQDHLNLLNREEEREMLPFCRDQGIGVLPWSPLARGRLARDGNESTSRQETDNYAKI
LYEKTEESDRAVIDAVGRIAAQRGVPRAQVALAWVLQTPGVTAPIVGASKPGQLADAVGALSLTLTAEEIAALAAPYVPH
PVVGFG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=33.974358974359, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=33.8709677419355, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=32.6923076923077, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=32.6923076923077, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=32.3717948717949, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI27436971, Length=313, Percent_Identity=31.9488817891374, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI223718702, Length=285, Percent_Identity=28.4210526315789, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI41152114, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI223718708, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=61.2307692307692, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=35.8895705521472, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.0229885057471, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=32.8267477203647, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=30.3630363036304, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786400, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI48994888, Length=290, Percent_Identity=26.8965517241379, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537079, Length=349, Percent_Identity=25.5014326647564, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561298, Length=309, Percent_Identity=23.9482200647249, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=41.0714285714286, Blast_Score=259, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=31.0650887573964, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=30.794701986755, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=29.2035398230088, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=31.9066147859922, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6321052, Length=169, Percent_Identity=31.9526627218935, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320079, Length=294, Percent_Identity=27.5510204081633, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324694, Length=237, Percent_Identity=28.6919831223629, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646155, Length=296, Percent_Identity=30.4054054054054, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646159, Length=313, Percent_Identity=28.4345047923323, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640980, Length=328, Percent_Identity=25, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI45549126, Length=328, Percent_Identity=25, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644950, Length=317, Percent_Identity=26.813880126183, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36018; Mature: 36018

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYTRLGRTGLQVSRICLGCMTYGVPERGNHPWTLDEETSRPLIRQALDAGINFLDTANT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YSDGTSEEIVGRAIRDFARREEIVLATKVFFPQRKGPNGGGLSRKAILGEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDPETPIEETMEALHDVVKAGKARYIGASSMYAWQFAKAVYTSRLNGWTE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
FVSMQDHLNLLNREEEREMLPFCRDQGIGVLPWSPLARGRLARDGNESTSRQETDNYAKI
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
LYEKTEESDRAVIDAVGRIAAQRGVPRAQVALAWVLQTPGVTAPIVGASKPGQLADAVGA
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LSLTLTAEEIAALAAPYVPHPVVGFG
HHEEEEHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEYTRLGRTGLQVSRICLGCMTYGVPERGNHPWTLDEETSRPLIRQALDAGINFLDTANT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YSDGTSEEIVGRAIRDFARREEIVLATKVFFPQRKGPNGGGLSRKAILGEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDPETPIEETMEALHDVVKAGKARYIGASSMYAWQFAKAVYTSRLNGWTE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
FVSMQDHLNLLNREEEREMLPFCRDQGIGVLPWSPLARGRLARDGNESTSRQETDNYAKI
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
LYEKTEESDRAVIDAVGRIAAQRGVPRAQVALAWVLQTPGVTAPIVGASKPGQLADAVGA
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LSLTLTAEEIAALAAPYVPHPVVGFG
HHEEEEHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]