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The map label for this gene is ygjG [C]

Identifier: 162146248

GI number: 162146248

Start: 421483

End: 422916

Strand: Direct

Name: ygjG [C]

Synonym: GDI_0423

Alternate gene names: 162146248

Gene position: 421483-422916 (Clockwise)

Preceding gene: 162146247

Following gene: 162146253

Centisome position: 10.69

GC content: 70.15

Gene sequence:

>1434_bases
ATGAACGTAGAAGCACTTCTCCGGACCGACCGGGATCATCTCATCCATCCGGTCTCGTCCTGGCGGGATCACGAGGCAGC
CGGGGCCCGCATCCTGCGCTCGGGCAAGGGCGCCTGGGTCACCGACATCCATGGCCGCGAACTGCTGGACGGGTTTTCCG
GCCTGTGGTGCGTCAATGTCGGCTATGGCTGCCAGAGCGTGGTCGATGCCGCCGCCGAACAGATGGCGCGCCTGCCCTAT
GCCACCGGCTATTTCGGTTTCGCCAGCGAGGCGGCGATCGAACTCGCCGGCCGCCTCGCGGCCCGGACGCCCGGCGACCT
GAACCGCGTCTTCTTTTCCCAGGGCGGATCGGACGCGGTGGACAGCGCCCTGCGCTTCATCCGCTTCTACCAGCATGCGC
GCGGCACGCCGCAGAAGCGGCACGTCATCGGCCTGTCGCGCGGCTATCACGGCTCGACCTACACCGGCGCGGGCCTGACC
GCGCTGGCCGCCTTCCATCGCGACGCGGATGTGCCGCTGGCGTGGCAGCATCATATTCCCAGCCCCTATCCCTACCGCCA
CGCGGGGGACGGCCAGGCGGCGACGATCATCGCGGAATCGGTCGCGGCCCTGCGGCGCAAGGTCGACGAACTGGGCGCCG
ACCAGGTCGCGGCCTTCTTCTGCGAGCCGGTGCAGGGGTCTGGCGGCGTGATCGTGCCGCCGCGCGGCTGGCTGGCCGCG
ATGCGGCGCACCTGCGCCGAACTCGACATCCTGTTCGTCGCGGACGAGGTCATCACCGGGTTCGGCCGGACCGGCCCGCT
CTTCGCCTGCGAGGCCGAGCAGGTTGTCCCCGACATGATGACCGTCGCCAAGGGCCTGACCTCCGGCTACGCCCCGATGG
GCGCGGTCTTCATGTCCGACGCCATCTACGCGACCATCCGCGACAACACGCCCGCCGGCATTCCCGTCGGGCACGGCATG
ACCTACAGCGCCCATCCCGTCAGTGCCGCGATCGGCCTCGCGGTCCTGGACCTGTACGAGGGCGGCATGCTGGACAACGG
ACTTCGGGCCGGCGCCCATCTCGCCACCCGCCTGGCCGCGCTGTCCGACCATCCCTGGTCGGCGATGTCCGGATCAGCGG
CATGCTGGCCGGGATCGAGCTGGTGTCCGACAAGGCGACCAAGCGCAAGCCGGAACCGGACCTCCAGGTCGCGGCCCGGC
TGTCCAAGGCCGGGTACGAGGCCGGGATTCTCTTCCGCGCCTTCGGTGACGACATCATCGGCCTCGCCCCGCCGCTGTGC
TGCACGATCGAGGAAATCGACGTGCTCTGCGACCGCCTCCATCGCATCATCGACGGCCTGCTTCCGCTCATCGGATAGAA
TCCGGCTCCCGCCCCGCCTCCGCTCCGGCGCCTATCGCCGGTTCGGGGGCGGGGCGGCCTCGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGCCACATCGTCTGTGTCGCCTGGGCACAATCCGGTTCCGGATCGGGTGAATCGCCCTTCCAGACCTACCGACGACGAAA
CAGCCGGGATCGATCGCGAC

Downstream 100 bases:

>100_bases
AGCCGCTGGAGGGAATTGGGAAAGCCCATCGCCTCGCGATATTTCGCGACCGTGCGGCGTGCGATGTCGATGCCCTGCCG
GCGCAGGGTCAGGGAAATCG

Product: aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MNVEALLRTDRDHLIHPVSSWRDHEAAGARILRSGKGAWVTDIHGRELLDGFSGLWCVNVGYGCQSVVDAAAEQMARLPY
ATGYFGFASEAAIELAGRLAARTPGDLNRVFFSQGGSDAVDSALRFIRFYQHARGTPQKRHVIGLSRGYHGSTYTGAGLT
ALAAFHRDADVPLAWQHHIPSPYPYRHAGDGQAATIIAESVAALRRKVDELGADQVAAFFCEPVQGSGGVIVPPRGWLAA
MRRTCAELDILFVADEVITGFGRTGPLFACEAEQVVPDMMTVAKGLTSGYAPMGAVFMSDAIYATIRDNTPAGIPVGHGM
TYSAHPVSAAIGLAVLDLYEGGMLDNGLRAGAHLATRLAALSDHPWSAMSGSAACWPGSSWCPTRRPSASRNRTSRSRPG
CPRPGTRPGFSSAPSVTTSSASPRRCAARSRKSTCSATASIASSTACFRSSDRIRLPPRLRSGAYRRFGGGAASAAR

Sequences:

>Translated_477_residues
MNVEALLRTDRDHLIHPVSSWRDHEAAGARILRSGKGAWVTDIHGRELLDGFSGLWCVNVGYGCQSVVDAAAEQMARLPY
ATGYFGFASEAAIELAGRLAARTPGDLNRVFFSQGGSDAVDSALRFIRFYQHARGTPQKRHVIGLSRGYHGSTYTGAGLT
ALAAFHRDADVPLAWQHHIPSPYPYRHAGDGQAATIIAESVAALRRKVDELGADQVAAFFCEPVQGSGGVIVPPRGWLAA
MRRTCAELDILFVADEVITGFGRTGPLFACEAEQVVPDMMTVAKGLTSGYAPMGAVFMSDAIYATIRDNTPAGIPVGHGM
TYSAHPVSAAIGLAVLDLYEGGMLDNGLRAGAHLATRLAALSDHPWSAMSGSAACWPGSSWCPTRRPSASRNRTSRSRPG
CPRPGTRPGFSSAPSVTTSSASPRRCAARSRKSTCSATASIASSTACFRSSDRIRLPPRLRSGAYRRFGGGAASAAR
>Mature_477_residues
MNVEALLRTDRDHLIHPVSSWRDHEAAGARILRSGKGAWVTDIHGRELLDGFSGLWCVNVGYGCQSVVDAAAEQMARLPY
ATGYFGFASEAAIELAGRLAARTPGDLNRVFFSQGGSDAVDSALRFIRFYQHARGTPQKRHVIGLSRGYHGSTYTGAGLT
ALAAFHRDADVPLAWQHHIPSPYPYRHAGDGQAATIIAESVAALRRKVDELGADQVAAFFCEPVQGSGGVIVPPRGWLAA
MRRTCAELDILFVADEVITGFGRTGPLFACEAEQVVPDMMTVAKGLTSGYAPMGAVFMSDAIYATIRDNTPAGIPVGHGM
TYSAHPVSAAIGLAVLDLYEGGMLDNGLRAGAHLATRLAALSDHPWSAMSGSAACWPGSSWCPTRRPSASRNRTSRSRPG
CPRPGTRPGFSSAPSVTTSSASPRRCAARSRKSTCSATASIASSTACFRSSDRIRLPPRLRSGAYRRFGGGAASAAR

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=343, Percent_Identity=31.4868804664723, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI226442705, Length=340, Percent_Identity=31.7647058823529, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI13994255, Length=378, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442709, Length=302, Percent_Identity=32.4503311258278, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI4557809, Length=352, Percent_Identity=27.5568181818182, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI24119277, Length=338, Percent_Identity=29.2899408284024, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI284507298, Length=159, Percent_Identity=36.4779874213836, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI145693181, Length=330, Percent_Identity=33.9393939393939, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786991, Length=344, Percent_Identity=31.3953488372093, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787560, Length=298, Percent_Identity=34.2281879194631, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788044, Length=316, Percent_Identity=30.379746835443, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1789016, Length=355, Percent_Identity=29.2957746478873, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789759, Length=351, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=381, Percent_Identity=29.3963254593176, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=346, Percent_Identity=24.8554913294798, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=170, Percent_Identity=32.3529411764706, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71992977, Length=339, Percent_Identity=26.2536873156342, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324386, Length=380, Percent_Identity=27.8947368421053, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=321, Percent_Identity=24.2990654205607, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323470, Length=340, Percent_Identity=25.5882352941176, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=353, Percent_Identity=23.2294617563739, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161085790, Length=387, Percent_Identity=32.2997416020672, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574759, Length=387, Percent_Identity=32.2997416020672, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357415, Length=352, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356575, Length=334, Percent_Identity=29.6407185628743, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50576; Mature: 50576

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVEALLRTDRDHLIHPVSSWRDHEAAGARILRSGKGAWVTDIHGRELLDGFSGLWCVNV
CCCHHHHHCCHHHHHCCHHHCCCHHHHHHHHHHCCCCCEEECCCCHHHHHCCCCEEEEEC
GYGCQSVVDAAAEQMARLPYATGYFGFASEAAIELAGRLAARTPGDLNRVFFSQGGSDAV
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
DSALRFIRFYQHARGTPQKRHVIGLSRGYHGSTYTGAGLTALAAFHRDADVPLAWQHHIP
HHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCC
SPYPYRHAGDGQAATIIAESVAALRRKVDELGADQVAAFFCEPVQGSGGVIVPPRGWLAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEECCCHHHHH
MRRTCAELDILFVADEVITGFGRTGPLFACEAEQVVPDMMTVAKGLTSGYAPMGAVFMSD
HHHHHHHHHEEEEEHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AIYATIRDNTPAGIPVGHGMTYSAHPVSAAIGLAVLDLYEGGMLDNGLRAGAHLATRLAA
CEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LSDHPWSAMSGSAACWPGSSWCPTRRPSASRNRTSRSRPGCPRPGTRPGFSSAPSVTTSS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASPRRCAARSRKSTCSATASIASSTACFRSSDRIRLPPRLRSGAYRRFGGGAASAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MNVEALLRTDRDHLIHPVSSWRDHEAAGARILRSGKGAWVTDIHGRELLDGFSGLWCVNV
CCCHHHHHCCHHHHHCCHHHCCCHHHHHHHHHHCCCCCEEECCCCHHHHHCCCCEEEEEC
GYGCQSVVDAAAEQMARLPYATGYFGFASEAAIELAGRLAARTPGDLNRVFFSQGGSDAV
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
DSALRFIRFYQHARGTPQKRHVIGLSRGYHGSTYTGAGLTALAAFHRDADVPLAWQHHIP
HHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCC
SPYPYRHAGDGQAATIIAESVAALRRKVDELGADQVAAFFCEPVQGSGGVIVPPRGWLAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEECCCHHHHH
MRRTCAELDILFVADEVITGFGRTGPLFACEAEQVVPDMMTVAKGLTSGYAPMGAVFMSD
HHHHHHHHHEEEEEHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AIYATIRDNTPAGIPVGHGMTYSAHPVSAAIGLAVLDLYEGGMLDNGLRAGAHLATRLAA
CEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LSDHPWSAMSGSAACWPGSSWCPTRRPSASRNRTSRSRPGCPRPGTRPGFSSAPSVTTSS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASPRRCAARSRKSTCSATASIASSTACFRSSDRIRLPPRLRSGAYRRFGGGAASAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]