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The map label for this gene is iolC [H]

Identifier: 162146189

GI number: 162146189

Start: 372258

End: 374186

Strand: Direct

Name: iolC [H]

Synonym: GDI_0361

Alternate gene names: 162146189

Gene position: 372258-374186 (Clockwise)

Preceding gene: 162146184

Following gene: 162146190

Centisome position: 9.44

GC content: 70.61

Gene sequence:

>1929_bases
ATGACGAACCCTGCACTTGACGTCGTGACGGTCGGCCGCGCGTCGGTCGATCTGTACGGGCAGCAGATCGGCGGCCGGCT
GGAGGACATGGCCAGCTTCAGCAAGGCCGTCGGCGGCTGCCCCGCCAACATCGCCATCGGCACCGCGCGGCTGGGCCTGA
AATCGGCGCTGGTCACCCGGGTCGGGGACGAGCATTTCGGGCGCTTCATCCGCGAACAGCTCTGCCGCGAAGGGGTGGAC
GTGCGGGGCGTGCACACCGACCCGGCCCGCTTCACCGCGCTGGCCATCCTGGGCGTGCGCGACCGGACCACGTTCCCGCT
GCTGTTCTACCGCACCGACTGCGCCGACAGCGCCCTGGACGAGGGCGATATCGACGAGGCCCTGATCCGGTCCAGCCGTG
TCCTGGTCGTGACCGGCACGCATTTCGCCCGGCCCGGCTCCGCCGCCGCGCAGCGCAAGGCCATGCGGATCATCCGCGCC
GCCGGCGGCAAGGTGGTGTTCGACATCGACTACCGCCCCAACCTGTGGGGCCTGGCCGGCATCGGGGACGGCGAGGCGCG
CTATGTCCGATCGGACACCGTCACCAGCCACCTGGCGCCGATCCTGCCGGACTGCGACCTGATCGTCGGCACCGAGGAGG
AACTGCATATCGCCGGCGGGTCGGAAGACACGCTGGATGCCATCCGCGCCATCCGCGCGCGCTCGGCCGCCACCATCGTG
TGCAAGCGCGGGCCGATGGGCTGCGTGGTGTTCGACGGTGCGATCCCGGACCGGCTGGATGACGGCATTTCCGGCCCCGG
CTTCCCGGTCGAGGTCTACAACACGCTGGGCGCGGGCGATGCCTTCATGTCGGGCTTCCTGCGCGGCTGGGTGCGGGGCG
AGGCGCTGGAGACCTGCTGCCGCTACGCCAATGCCTGCGGCGCCTTCGCGGTGTCGCGCCTGCTGTGCTCGCCCGAAATC
CCGACCTGGCGGGAACTGACCTATTTCCTCGACCATGGCAGCGTGGAAACCGCGCTGCGGCATGATGTCGCGCTGAATCA
CCTGCACTGGGTCACCACGCGGCGCGCCCAGGCCTATCCGGTCATGGCGCTGGCCTGCGACCATCGCATCCAGCTCGAAG
CCATCGCGCTGGAAGCCGGGGCCCCGCTGTCGCGCATTCCGCAGTTCAAGACGCTCGCGGTGCAGGCGGCGGTCAGGGTG
GCGAACGGCGCACCGGGCTTCGGCGTCTTCATGGACGGGCGCTACGGCCAGGACGCGCTGTTCACCGCGTCGAAGAGCGG
TCTGTGGACGGCCCGCCCGATCGAACTGCCGGCCTCGCGCCCGCTGGATTTCGAGTTCGGCGGCAGCCTGGGCGCCCACC
TGACCGAATGGCCGACCGACCAGGTGGTGAAATGCCTGTGCTTCTACCACCCGGACGATGACGAGGCCCTGCGCCAGCGC
CAGGAACGCGAAATGCTGCGCGCGCAGGATGCCTGCCGCCGGACCGGCCGCGAGCTGCTGCTGGAAATCATCGCCGGCAA
GAACGGCCCGATGCGCGACGACACGGTGTCCCGCGCGTTGCAGATGCTCTACGCCGCCGGGCTGCGCCCGGACTGGTGGA
AGCTGGAAGGACAGTCCAGCCCCGCCGCCTGGCACGCCATCGGCGAGGTGATCGGCGCGAACGACCCCGATTGCCGGGGC
GTCGTCATCCTGGGCCTGGACGCGCCCGAACAGGAATTGCTGGCCGCGTTCCAGGCCGCCGCGGTCACGCCCTGGGTCCG
GGGCTTCGCGATCGGCCGCACCATCTTCGGCGACCCGGCACGCGCCTGGTTCGCGGGCAGCCTGGACGACGCAGGCGCGG
TCGATGAAATGAGCCGCCGTTTCGCGCGCTTCGTCGCCGCCTGGCAGGCGGTGCCGCGCACCACCGACGCAACGGGACAA
CGGTCATGA

Upstream 100 bases:

>100_bases
AAACGGAATAAACGTTCTGTGATTTGACGCAAAGGGAACATTTATCCCTAAATCGCCGCCAAGCAGGCCCGCCAAGAGGT
CGCCCGAAAAGAGGTAAGGA

Downstream 100 bases:

>100_bases
ACACGATCCGCCTGACCATGGCACAGGCGCTGGTCCGCGCCATGTGCGCGCAGAAGACCGAGCTGGACGGCCAGATCGTG
CCGTTCTTCGGCGGTGTCTG

Product: myo-inositol catabolism, sugar kinase protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MTNPALDVVTVGRASVDLYGQQIGGRLEDMASFSKAVGGCPANIAIGTARLGLKSALVTRVGDEHFGRFIREQLCREGVD
VRGVHTDPARFTALAILGVRDRTTFPLLFYRTDCADSALDEGDIDEALIRSSRVLVVTGTHFARPGSAAAQRKAMRIIRA
AGGKVVFDIDYRPNLWGLAGIGDGEARYVRSDTVTSHLAPILPDCDLIVGTEEELHIAGGSEDTLDAIRAIRARSAATIV
CKRGPMGCVVFDGAIPDRLDDGISGPGFPVEVYNTLGAGDAFMSGFLRGWVRGEALETCCRYANACGAFAVSRLLCSPEI
PTWRELTYFLDHGSVETALRHDVALNHLHWVTTRRAQAYPVMALACDHRIQLEAIALEAGAPLSRIPQFKTLAVQAAVRV
ANGAPGFGVFMDGRYGQDALFTASKSGLWTARPIELPASRPLDFEFGGSLGAHLTEWPTDQVVKCLCFYHPDDDEALRQR
QEREMLRAQDACRRTGRELLLEIIAGKNGPMRDDTVSRALQMLYAAGLRPDWWKLEGQSSPAAWHAIGEVIGANDPDCRG
VVILGLDAPEQELLAAFQAAAVTPWVRGFAIGRTIFGDPARAWFAGSLDDAGAVDEMSRRFARFVAAWQAVPRTTDATGQ
RS

Sequences:

>Translated_642_residues
MTNPALDVVTVGRASVDLYGQQIGGRLEDMASFSKAVGGCPANIAIGTARLGLKSALVTRVGDEHFGRFIREQLCREGVD
VRGVHTDPARFTALAILGVRDRTTFPLLFYRTDCADSALDEGDIDEALIRSSRVLVVTGTHFARPGSAAAQRKAMRIIRA
AGGKVVFDIDYRPNLWGLAGIGDGEARYVRSDTVTSHLAPILPDCDLIVGTEEELHIAGGSEDTLDAIRAIRARSAATIV
CKRGPMGCVVFDGAIPDRLDDGISGPGFPVEVYNTLGAGDAFMSGFLRGWVRGEALETCCRYANACGAFAVSRLLCSPEI
PTWRELTYFLDHGSVETALRHDVALNHLHWVTTRRAQAYPVMALACDHRIQLEAIALEAGAPLSRIPQFKTLAVQAAVRV
ANGAPGFGVFMDGRYGQDALFTASKSGLWTARPIELPASRPLDFEFGGSLGAHLTEWPTDQVVKCLCFYHPDDDEALRQR
QEREMLRAQDACRRTGRELLLEIIAGKNGPMRDDTVSRALQMLYAAGLRPDWWKLEGQSSPAAWHAIGEVIGANDPDCRG
VVILGLDAPEQELLAAFQAAAVTPWVRGFAIGRTIFGDPARAWFAGSLDDAGAVDEMSRRFARFVAAWQAVPRTTDATGQ
RS
>Mature_641_residues
TNPALDVVTVGRASVDLYGQQIGGRLEDMASFSKAVGGCPANIAIGTARLGLKSALVTRVGDEHFGRFIREQLCREGVDV
RGVHTDPARFTALAILGVRDRTTFPLLFYRTDCADSALDEGDIDEALIRSSRVLVVTGTHFARPGSAAAQRKAMRIIRAA
GGKVVFDIDYRPNLWGLAGIGDGEARYVRSDTVTSHLAPILPDCDLIVGTEEELHIAGGSEDTLDAIRAIRARSAATIVC
KRGPMGCVVFDGAIPDRLDDGISGPGFPVEVYNTLGAGDAFMSGFLRGWVRGEALETCCRYANACGAFAVSRLLCSPEIP
TWRELTYFLDHGSVETALRHDVALNHLHWVTTRRAQAYPVMALACDHRIQLEAIALEAGAPLSRIPQFKTLAVQAAVRVA
NGAPGFGVFMDGRYGQDALFTASKSGLWTARPIELPASRPLDFEFGGSLGAHLTEWPTDQVVKCLCFYHPDDDEALRQRQ
EREMLRAQDACRRTGRELLLEIIAGKNGPMRDDTVSRALQMLYAAGLRPDWWKLEGQSSPAAWHAIGEVIGANDPDCRGV
VILGLDAPEQELLAAFQAAAVTPWVRGFAIGRTIFGDPARAWFAGSLDDAGAVDEMSRRFARFVAAWQAVPRTTDATGQR
S

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 69521; Mature: 69390

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPALDVVTVGRASVDLYGQQIGGRLEDMASFSKAVGGCPANIAIGTARLGLKSALVTR
CCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
VGDEHFGRFIREQLCREGVDVRGVHTDPARFTALAILGVRDRTTFPLLFYRTDCADSALD
CCHHHHHHHHHHHHHHCCCCEEECCCCCHHEEEEEEEECCCCCCCEEEEEECCCCCCCCC
EGDIDEALIRSSRVLVVTGTHFARPGSAAAQRKAMRIIRAAGGKVVFDIDYRPNLWGLAG
CCCHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
IGDGEARYVRSDTVTSHLAPILPDCDLIVGTEEELHIAGGSEDTLDAIRAIRARSAATIV
CCCCCCEEEECHHHHHHHHHCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCEEEE
CKRGPMGCVVFDGAIPDRLDDGISGPGFPVEVYNTLGAGDAFMSGFLRGWVRGEALETCC
ECCCCCEEEEECCCCCHHHHCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHCHHHHHHHH
RYANACGAFAVSRLLCSPEIPTWRELTYFLDHGSVETALRHDVALNHLHWVTTRRAQAYP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCC
VMALACDHRIQLEAIALEAGAPLSRIPQFKTLAVQAAVRVANGAPGFGVFMDGRYGQDAL
EEEEECCCCEEEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCE
FTASKSGLWTARPIELPASRPLDFEFGGSLGAHLTEWPTDQVVKCLCFYHPDDDEALRQR
EEECCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHEECCCCHHHHHHH
QEREMLRAQDACRRTGRELLLEIIAGKNGPMRDDTVSRALQMLYAAGLRPDWWKLEGQSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCC
PAAWHAIGEVIGANDPDCRGVVILGLDAPEQELLAAFQAAAVTPWVRGFAIGRTIFGDPA
CHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
RAWFAGSLDDAGAVDEMSRRFARFVAAWQAVPRTTDATGQRS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TNPALDVVTVGRASVDLYGQQIGGRLEDMASFSKAVGGCPANIAIGTARLGLKSALVTR
CCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
VGDEHFGRFIREQLCREGVDVRGVHTDPARFTALAILGVRDRTTFPLLFYRTDCADSALD
CCHHHHHHHHHHHHHHCCCCEEECCCCCHHEEEEEEEECCCCCCCEEEEEECCCCCCCCC
EGDIDEALIRSSRVLVVTGTHFARPGSAAAQRKAMRIIRAAGGKVVFDIDYRPNLWGLAG
CCCHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
IGDGEARYVRSDTVTSHLAPILPDCDLIVGTEEELHIAGGSEDTLDAIRAIRARSAATIV
CCCCCCEEEECHHHHHHHHHCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCEEEE
CKRGPMGCVVFDGAIPDRLDDGISGPGFPVEVYNTLGAGDAFMSGFLRGWVRGEALETCC
ECCCCCEEEEECCCCCHHHHCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHCHHHHHHHH
RYANACGAFAVSRLLCSPEIPTWRELTYFLDHGSVETALRHDVALNHLHWVTTRRAQAYP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCC
VMALACDHRIQLEAIALEAGAPLSRIPQFKTLAVQAAVRVANGAPGFGVFMDGRYGQDAL
EEEEECCCCEEEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCE
FTASKSGLWTARPIELPASRPLDFEFGGSLGAHLTEWPTDQVVKCLCFYHPDDDEALRQR
EEECCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHEECCCCHHHHHHH
QEREMLRAQDACRRTGRELLLEIIAGKNGPMRDDTVSRALQMLYAAGLRPDWWKLEGQSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCC
PAAWHAIGEVIGANDPDCRGVVILGLDAPEQELLAAFQAAAVTPWVRGFAIGRTIFGDPA
CHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
RAWFAGSLDDAGAVDEMSRRFARFVAAWQAVPRTTDATGQRS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA