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The map label for this gene is pdxA [H]

Identifier: 162146049

GI number: 162146049

Start: 233939

End: 234943

Strand: Direct

Name: pdxA [H]

Synonym: GDI_0217

Alternate gene names: 162146049

Gene position: 233939-234943 (Clockwise)

Preceding gene: 162146047

Following gene: 162146050

Centisome position: 5.93

GC content: 70.35

Gene sequence:

>1005_bases
ATGACCGCACCCTCCTCCTGCCACACCCGGCCGCTGGCCGTCACGATGGGCGATCCCGCCGGGATCGGGCCGGAGATCGC
GGCCCGGATGTTCCTGCGGCGGCCGGCGCAACGATGCTGGATCGTGGTCGGTGATCCGCTGGTGATGCGCCACGCCCTGG
CCGCGCGCGATCCGGCGGCGCGGATGCGCCGCATCGCGACGCCGGCCGAAGCCCGGTTCGATGACGGGGTGCTGAACGTC
CTGGCGTCATCGGAATGCGTGGCCCTGCCGCCCATAGGCCGTGTCAGCGCCGAAAGCGGCCGCGCCGCCTATGCGGCAAT
CCGCACCGCCATACGGTTGGCCAGGGATGGCGCGATCCGGGGCATCGTCACCGCGCCGATCCACAAGGAAGCGCTCGCCG
CCGCCGGATTGCCGTACCCCGGCCATACGGAAATCCTCGCCGAACAGGCCGGCGGCGCGCGTGTCGCCATGATGCTGGCG
AACGAGGATATCCGCGTCGTGCTGGTGACCATCCATTGTTCGCTGCGGGACGCGATCCGCCGCGCCGATCAATCCGCACA
GATGGCGGCGATCCGCCTCGCCCACGCGGGCGCACGCGCGCTGGGCGTCGAATGCCCGCGCGTCGCCGTGGCGGGCCTCA
ATCCCCATGCCGGGGAAGGCGGCCTGTTCGGCGAGGAGGAAACCCGCATCATCGCGCCCGCCATCGCACAGGCGCGGAGC
GAGGGCATCGATGCGTCCGGCCCGTGGCCCGGCGACACGGTGTTCATGCAGGCGCGGCAGAGGCGCTTCGATGTCGTGGT
GGCGCAATATCACGACCAGGGGCTGATTCCGGTGAAATATATGGGCCTGGCGCAGGGCGTGAACATCACGCTCGGCCTGC
CCTTCATCCGCACCAGCCCCGACCACGGCACCGCCTTCGATATCGCGGGACGCGGCGTTGCCGATCCGTCCAGCCTGGAG
ACGGCTTTCGATTACGCCCTTCGCCTCACCGGAGCCGCGACATGA

Upstream 100 bases:

>100_bases
GCGACGGGATGTCGGATCGCTTCATTGGTCAGTTTTTATCACCGGAACAGGTCAGTTCATATCGATTTTCCTCCGGAACC
GTTCCGCTATTCTCACCATC

Downstream 100 bases:

>100_bases
TCCGACCCGATTTCATCTTCATGCTGACCCGCCATGACCGGACGGTGGAGAATGCGGCCGATCTGGTGCAGACCGCCCGA
GCCGCGGGGGTCCGCCATAT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTAPSSCHTRPLAVTMGDPAGIGPEIAARMFLRRPAQRCWIVVGDPLVMRHALAARDPAARMRRIATPAEARFDDGVLNV
LASSECVALPPIGRVSAESGRAAYAAIRTAIRLARDGAIRGIVTAPIHKEALAAAGLPYPGHTEILAEQAGGARVAMMLA
NEDIRVVLVTIHCSLRDAIRRADQSAQMAAIRLAHAGARALGVECPRVAVAGLNPHAGEGGLFGEEETRIIAPAIAQARS
EGIDASGPWPGDTVFMQARQRRFDVVVAQYHDQGLIPVKYMGLAQGVNITLGLPFIRTSPDHGTAFDIAGRGVADPSSLE
TAFDYALRLTGAAT

Sequences:

>Translated_334_residues
MTAPSSCHTRPLAVTMGDPAGIGPEIAARMFLRRPAQRCWIVVGDPLVMRHALAARDPAARMRRIATPAEARFDDGVLNV
LASSECVALPPIGRVSAESGRAAYAAIRTAIRLARDGAIRGIVTAPIHKEALAAAGLPYPGHTEILAEQAGGARVAMMLA
NEDIRVVLVTIHCSLRDAIRRADQSAQMAAIRLAHAGARALGVECPRVAVAGLNPHAGEGGLFGEEETRIIAPAIAQARS
EGIDASGPWPGDTVFMQARQRRFDVVVAQYHDQGLIPVKYMGLAQGVNITLGLPFIRTSPDHGTAFDIAGRGVADPSSLE
TAFDYALRLTGAAT
>Mature_333_residues
TAPSSCHTRPLAVTMGDPAGIGPEIAARMFLRRPAQRCWIVVGDPLVMRHALAARDPAARMRRIATPAEARFDDGVLNVL
ASSECVALPPIGRVSAESGRAAYAAIRTAIRLARDGAIRGIVTAPIHKEALAAAGLPYPGHTEILAEQAGGARVAMMLAN
EDIRVVLVTIHCSLRDAIRRADQSAQMAAIRLAHAGARALGVECPRVAVAGLNPHAGEGGLFGEEETRIIAPAIAQARSE
GIDASGPWPGDTVFMQARQRRFDVVVAQYHDQGLIPVKYMGLAQGVNITLGLPFIRTSPDHGTAFDIAGRGVADPSSLET
AFDYALRLTGAAT

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=331, Percent_Identity=39.2749244712991, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35190; Mature: 35059

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00732 RIBOSOMAL_S16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSSCHTRPLAVTMGDPAGIGPEIAARMFLRRPAQRCWIVVGDPLVMRHALAARDPAA
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHEEEEECCHHHHHHHHHCCCHHH
RMRRIATPAEARFDDGVLNVLASSECVALPPIGRVSAESGRAAYAAIRTAIRLARDGAIR
HHHHHCCCCHHCCCCHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GIVTAPIHKEALAAAGLPYPGHTEILAEQAGGARVAMMLANEDIRVVLVTIHCSLRDAIR
EEEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHH
RADQSAQMAAIRLAHAGARALGVECPRVAVAGLNPHAGEGGLFGEEETRIIAPAIAQARS
HCCCHHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHH
EGIDASGPWPGDTVFMQARQRRFDVVVAQYHDQGLIPVKYMGLAQGVNITLGLPFIRTSP
CCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHHCCCEEEEECCEEEECC
DHGTAFDIAGRGVADPSSLETAFDYALRLTGAAT
CCCCEEEECCCCCCCCHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
TAPSSCHTRPLAVTMGDPAGIGPEIAARMFLRRPAQRCWIVVGDPLVMRHALAARDPAA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHEEEEECCHHHHHHHHHCCCHHH
RMRRIATPAEARFDDGVLNVLASSECVALPPIGRVSAESGRAAYAAIRTAIRLARDGAIR
HHHHHCCCCHHCCCCHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GIVTAPIHKEALAAAGLPYPGHTEILAEQAGGARVAMMLANEDIRVVLVTIHCSLRDAIR
EEEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHH
RADQSAQMAAIRLAHAGARALGVECPRVAVAGLNPHAGEGGLFGEEETRIIAPAIAQARS
HCCCHHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHH
EGIDASGPWPGDTVFMQARQRRFDVVVAQYHDQGLIPVKYMGLAQGVNITLGLPFIRTSP
CCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHHCCCEEEEECCEEEECC
DHGTAFDIAGRGVADPSSLETAFDYALRLTGAAT
CCCCEEEECCCCCCCCHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA