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The map label for this gene is hflX [H]

Identifier: 162145994

GI number: 162145994

Start: 170308

End: 171672

Strand: Direct

Name: hflX [H]

Synonym: GDI_0162

Alternate gene names: 162145994

Gene position: 170308-171672 (Clockwise)

Preceding gene: 162145989

Following gene: 162145996

Centisome position: 4.32

GC content: 70.04

Gene sequence:

>1365_bases
ATGTCACCATCCATGGAGACCAAACCCCCGATTCCGCTCGCCGTCCTCGTCGGCATCCAGACGCCGGACGTCGATGATAT
CGCGCACGAGGCCAGCCTAGCCGAACTGGGGCGCCTGGTGAAGACGCTGGGCTATGCGGTCGTCGGCACCGTGTCGCAGA
AGCGCGAAGGCACCGGCGCCGCATTGCTGCTGGGCAGCGGCAAGCTGGCGGAACTGGCCGCGCTGACCGGCGGCACCGGT
GTCGTGACCTCGATGGCCCCGCCCCCGAAATCCAAGGCCCGGCAGCGGTTCGAAGGCGCGGCCGAGGGCGCCGCGCCGCC
CGAGCCCGACCCGGACGCCGCCCGCAGGCCCGAATTCGTCATTGTCGACCATGAGCTCTCGCCCAGCCAGATCCGCAACC
TGGAACGCGCCACCGGCGCCCAGGTGCTGGACCGCACCGGCGTCATCGTCGAGATCTTCCACCGCCACGCCAACACCCGC
GAGGCACGGCTGCAGGTGGAGATGGCGCGCCTGAAATACGTGGCCCCCCGCCTGCGCGAATCCTCGGGCGGCGGCGGCCG
GCAGCAGGGTCCGGGTGCCGGCGAAAGCACCCTGGCGCTCGACCGCCGCAAGATCCGCGACCGGCTGGCGGAACTGAAGA
CCCAGCTTGACGCGGTGCAGCGCGACGGCGACCAGCGCCGGTCCGCCCGCCGCGACCAGCTTAGGGTGGCGCTGGTCGGC
TACACCAATGCGGGCAAATCCTCCCTGATGCGGGCGCTGACCGGCAGCCAGGTGCTGGTCGAGGACAAGCTGTTCGCCAC
CCTGGACACCACCGTCCGCATCCTGCAGCCCGAAACCCGCCCCCGCATCCTGGTTTCCGACACGGTCGGCTTCATCAAGC
AATTGCCGCACGATTTGGTGGCCTCGTTCCGCTCCACCCTGGCCGAGGCGCTGGAGGCCTCGCTGCTGCTGTTCGTGGTC
GATGCGTCGGACCCGACCTACGAGTCCCAACTGGAGGTGACGCGCGGCGTGCTGCGGGAAATCGGGGCCGACGCCGTGCC
GTCCCGCCTGGTCCTGAACAAGATGGACCGGCTGGACCCCGCCGCCCGCGCCGCGCTGCGGGACAAGCACCCCGACGCCA
TCATGCTTTCCGCCCACGCGCCCGGGGACGTCAGCGCATTGCGCGACACCCTGATCGCGTTCTTCGAGGCCGAGATGGTG
GAGGACACCCTGGTGCTGCCCTACGCGAAACAGGGCCTGATCGGCGAAATCTATGAAAGCGCCCGCGTCCTGTCCGAAGA
CCATGACGAGACCGGCCGCGTGCTGAAGGTCCGCGCCCTGCCCGCCGCCATCACCCGCCTGAAGCGAAGCCTCGCCGCGC
GCTGA

Upstream 100 bases:

>100_bases
CGACCGGCAGCAGGTTTCCAGGTACGGTTCGGTCCACATGGGCCCGAGGATCGGCGTTTCGCGGCCGGCTTGCAACCGAA
CAGCGGGCCGTATCCGTGCT

Downstream 100 bases:

>100_bases
AACATCGATGCGGCCCGGGTTGCGCTACGCCGCTGGGTGGAAGGCGGCCGCGCTGGCGAATTCGATGCGGTTTCGACCGA
GGGTCTTCGCCTGGTACAGG

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSPSMETKPPIPLAVLVGIQTPDVDDIAHEASLAELGRLVKTLGYAVVGTVSQKREGTGAALLLGSGKLAELAALTGGTG
VVTSMAPPPKSKARQRFEGAAEGAAPPEPDPDAARRPEFVIVDHELSPSQIRNLERATGAQVLDRTGVIVEIFHRHANTR
EARLQVEMARLKYVAPRLRESSGGGGRQQGPGAGESTLALDRRKIRDRLAELKTQLDAVQRDGDQRRSARRDQLRVALVG
YTNAGKSSLMRALTGSQVLVEDKLFATLDTTVRILQPETRPRILVSDTVGFIKQLPHDLVASFRSTLAEALEASLLLFVV
DASDPTYESQLEVTRGVLREIGADAVPSRLVLNKMDRLDPAARAALRDKHPDAIMLSAHAPGDVSALRDTLIAFFEAEMV
EDTLVLPYAKQGLIGEIYESARVLSEDHDETGRVLKVRALPAAITRLKRSLAAR

Sequences:

>Translated_454_residues
MSPSMETKPPIPLAVLVGIQTPDVDDIAHEASLAELGRLVKTLGYAVVGTVSQKREGTGAALLLGSGKLAELAALTGGTG
VVTSMAPPPKSKARQRFEGAAEGAAPPEPDPDAARRPEFVIVDHELSPSQIRNLERATGAQVLDRTGVIVEIFHRHANTR
EARLQVEMARLKYVAPRLRESSGGGGRQQGPGAGESTLALDRRKIRDRLAELKTQLDAVQRDGDQRRSARRDQLRVALVG
YTNAGKSSLMRALTGSQVLVEDKLFATLDTTVRILQPETRPRILVSDTVGFIKQLPHDLVASFRSTLAEALEASLLLFVV
DASDPTYESQLEVTRGVLREIGADAVPSRLVLNKMDRLDPAARAALRDKHPDAIMLSAHAPGDVSALRDTLIAFFEAEMV
EDTLVLPYAKQGLIGEIYESARVLSEDHDETGRVLKVRALPAAITRLKRSLAAR
>Mature_453_residues
SPSMETKPPIPLAVLVGIQTPDVDDIAHEASLAELGRLVKTLGYAVVGTVSQKREGTGAALLLGSGKLAELAALTGGTGV
VTSMAPPPKSKARQRFEGAAEGAAPPEPDPDAARRPEFVIVDHELSPSQIRNLERATGAQVLDRTGVIVEIFHRHANTRE
ARLQVEMARLKYVAPRLRESSGGGGRQQGPGAGESTLALDRRKIRDRLAELKTQLDAVQRDGDQRRSARRDQLRVALVGY
TNAGKSSLMRALTGSQVLVEDKLFATLDTTVRILQPETRPRILVSDTVGFIKQLPHDLVASFRSTLAEALEASLLLFVVD
ASDPTYESQLEVTRGVLREIGADAVPSRLVLNKMDRLDPAARAALRDKHPDAIMLSAHAPGDVSALRDTLIAFFEAEMVE
DTLVLPYAKQGLIGEIYESARVLSEDHDETGRVLKVRALPAAITRLKRSLAAR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=150, Percent_Identity=38.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI310133116, Length=150, Percent_Identity=39.3333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI310124269, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124267, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124171, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310124169, Length=142, Percent_Identity=40.1408450704225, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1790615, Length=437, Percent_Identity=35.2402745995423, Blast_Score=221, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17561038, Length=244, Percent_Identity=33.6065573770492, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24650079, Length=256, Percent_Identity=33.59375, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49051; Mature: 48920

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSMETKPPIPLAVLVGIQTPDVDDIAHEASLAELGRLVKTLGYAVVGTVSQKREGTGA
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALLLGSGKLAELAALTGGTGVVTSMAPPPKSKARQRFEGAAEGAAPPEPDPDAARRPEFV
EEEECCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEE
IVDHELSPSQIRNLERATGAQVLDRTGVIVEIFHRHANTREARLQVEMARLKYVAPRLRE
EEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
SSGGGGRQQGPGAGESTLALDRRKIRDRLAELKTQLDAVQRDGDQRRSARRDQLRVALVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEE
YTNAGKSSLMRALTGSQVLVEDKLFATLDTTVRILQPETRPRILVSDTVGFIKQLPHDLV
ECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHCCHHHH
ASFRSTLAEALEASLLLFVVDASDPTYESQLEVTRGVLREIGADAVPSRLVLNKMDRLDP
HHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCH
AARAALRDKHPDAIMLSAHAPGDVSALRDTLIAFFEAEMVEDTLVLPYAKQGLIGEIYES
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEECCCHHCCHHHHHHHH
ARVLSEDHDETGRVLKVRALPAAITRLKRSLAAR
HHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPSMETKPPIPLAVLVGIQTPDVDDIAHEASLAELGRLVKTLGYAVVGTVSQKREGTGA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALLLGSGKLAELAALTGGTGVVTSMAPPPKSKARQRFEGAAEGAAPPEPDPDAARRPEFV
EEEECCCCHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEE
IVDHELSPSQIRNLERATGAQVLDRTGVIVEIFHRHANTREARLQVEMARLKYVAPRLRE
EEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
SSGGGGRQQGPGAGESTLALDRRKIRDRLAELKTQLDAVQRDGDQRRSARRDQLRVALVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEE
YTNAGKSSLMRALTGSQVLVEDKLFATLDTTVRILQPETRPRILVSDTVGFIKQLPHDLV
ECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHCCHHHH
ASFRSTLAEALEASLLLFVVDASDPTYESQLEVTRGVLREIGADAVPSRLVLNKMDRLDP
HHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCH
AARAALRDKHPDAIMLSAHAPGDVSALRDTLIAFFEAEMVEDTLVLPYAKQGLIGEIYES
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEECCCHHCCHHHHHHHH
ARVLSEDHDETGRVLKVRALPAAITRLKRSLAAR
HHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]