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The map label for this gene is cueR [H]

Identifier: 162145920

GI number: 162145920

Start: 97178

End: 97711

Strand: Direct

Name: cueR [H]

Synonym: GDI_0084

Alternate gene names: 162145920

Gene position: 97178-97711 (Clockwise)

Preceding gene: 162145913

Following gene: 162145922

Centisome position: 2.46

GC content: 64.98

Gene sequence:

>534_bases
ATGAAGATCGGTGACCTCGCGAAACAGACCGGCCTCGCGCCCTCACGCATTCGCTTTTACGAAAGCATCGGCCTGCTGAC
GGCCGTGGAGCGCAAGGCCAATGGCTACCGGACCTATCCGCCGGATGCGGCCGTTATTCTCGGCCTGATCGCCACCGCCC
AGAAAGCGGGGTTCACGCTGGACGAGATTCGCGTCCTGCTGCCAAGCGACCTGAAGGATTGGGATCATGACGCGCTGATC
GGTGCGCTGACGCGCAAGGTCGCCGATATCGAGGCGCTGGAAGGCCGCCTCGCCCAGAACAAGGCGCAGTTGCGTCACGT
CATCGAAAGCATCGAGACGCGACCAGCGGATCTGGACTGTGCCGACAACGCACGTCGCGTGCTGACGCATATCCTGAATG
GCGATGAGGAGACGGCGGACGCCCGCACAGGGAGCGCTCCCCGGTCCAGGCCAATGGCTTCCCGCGAGCCCTCTGGTGCG
GCGCGGGCCAGACGCGCCGGTGCTGACACGTCGCCGGTTTCAGAGCAGGTCTGA

Upstream 100 bases:

>100_bases
CAATCCAGCTCCATGAGGCCGACTCCGTGAGGAACACTCTGGTCAGAGCGTGACATTAAAGGTAACTTTAAGGTCAAGGA
TCATCTTCGGGAGACGGAGC

Downstream 100 bases:

>100_bases
AATCCTGCGTGCCGTGGCCTTGGCCGAGGCGGGATTCTGCCCGGTGATCAGGCGACCATCCGCGACGACGTGGGGCACGA
AGGGCAGGAATGCTTTATCG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKIGDLAKQTGLAPSRIRFYESIGLLTAVERKANGYRTYPPDAAVILGLIATAQKAGFTLDEIRVLLPSDLKDWDHDALI
GALTRKVADIEALEGRLAQNKAQLRHVIESIETRPADLDCADNARRVLTHILNGDEETADARTGSAPRSRPMASREPSGA
ARARRAGADTSPVSEQV

Sequences:

>Translated_177_residues
MKIGDLAKQTGLAPSRIRFYESIGLLTAVERKANGYRTYPPDAAVILGLIATAQKAGFTLDEIRVLLPSDLKDWDHDALI
GALTRKVADIEALEGRLAQNKAQLRHVIESIETRPADLDCADNARRVLTHILNGDEETADARTGSAPRSRPMASREPSGA
ARARRAGADTSPVSEQV
>Mature_177_residues
MKIGDLAKQTGLAPSRIRFYESIGLLTAVERKANGYRTYPPDAAVILGLIATAQKAGFTLDEIRVLLPSDLKDWDHDALI
GALTRKVADIEALEGRLAQNKAQLRHVIESIETRPADLDCADNARRVLTHILNGDEETADARTGSAPRSRPMASREPSGA
ARARRAGADTSPVSEQV

Specific function: Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 19138; Mature: 19138

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGDLAKQTGLAPSRIRFYESIGLLTAVERKANGYRTYPPDAAVILGLIATAQKAGFTL
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
DEIRVLLPSDLKDWDHDALIGALTRKVADIEALEGRLAQNKAQLRHVIESIETRPADLDC
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADNARRVLTHILNGDEETADARTGSAPRSRPMASREPSGAARARRAGADTSPVSEQV
HHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKIGDLAKQTGLAPSRIRFYESIGLLTAVERKANGYRTYPPDAAVILGLIATAQKAGFTL
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
DEIRVLLPSDLKDWDHDALIGALTRKVADIEALEGRLAQNKAQLRHVIESIETRPADLDC
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADNARRVLTHILNGDEETADARTGSAPRSRPMASREPSGAARARRAGADTSPVSEQV
HHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]