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The map label for this gene is prc [C]

Identifier: 162145882

GI number: 162145882

Start: 45348

End: 47138

Strand: Reverse

Name: prc [C]

Synonym: GDI_0043

Alternate gene names: 162145882

Gene position: 47138-45348 (Counterclockwise)

Preceding gene: 162145883

Following gene: 162145881

Centisome position: 1.2

GC content: 72.25

Gene sequence:

>1791_bases
ATGCGCGCGCCATCCGTTCCCGTTCCGGCGGGCCCCGTTTCGGCGGGCTGGATCCCCGCCCCGCTCCGTGGGGCCGGGCG
ACGGGTCACGTCCGTGATCCTGCCGACGCGCACGATCGCCATCATGCTGATCGTCATCCACCTGATGACGCCCGTCCTGG
CCCCCGTGGCGGCGCGCGCCGCCGGCACGCCCGCGCCACCCCCGCCCCCCCGGCCCGCGCCGACCCCCGGACAGGATACG
AGGAGCCAGGATACGAGCCAGATTCTGGTCCAGGCGGACCCGGTGCCCCAGGCGGGCCAGTTGGACGCGGACATGACGAT
ATCGGTCGTGAACGCGGCCCTGACCTTCCTGCTGCCCCGAACGCTGGAGAGCCACACGCCGCGCGATTTCTGCCTGTGGG
GCCTGAACGGGCTGAGCGCGATCGACCCGTCCCTGACCGTCGTCGAGCAGAGGGGGCCCGAACAGAAAGGGGCGAACCAG
AACGGGATCATCCAGCTTTCGCTGGGGCAGGAAATCGTGCTGCGCCTGCCCGCCCCCCCCGATTCCGACCAGGCGGGATG
GACGGACCTGACCGTGCGGTTGATGCAGGCGGCCTGGGCCCGGTCGGGCACGGTGCGCGGCGCCGGCGCGGACGGTCTGA
TGCAAAGCTTCTTCGACGAACTGTTCAACCACATGGACCCGTATTCGCGTTACGTCGCGCCCAGCCCGGCCACGACCGAC
CGCGACACGCGCACCGGCGGCGAGGCCGGGACCGGGCTGACATTGGGCCGCGACGCGCGCTCGATCCTGATCACCGGGGT
CAATGCCAACGGGCCGGCCTGGCCGGCGGGTCTGGCGACGGGCCAGCGGCTGTACGCGGTCAATGGCCGTTCGACCCGTG
ACCAGACGCCCGGAACGGTCGCCCAGTGGCTGCTGGGTGCGCCCGGCAGCACGGTGACGGTGACGGTTGGCGACGGGCGC
GCCCGGCGCACCGTGACGCTGCGCCGGGCCTCGGTCCCGCCGGAGACGGTCTTCGCCTATGCCGCGGAACATATGGTGGT
GATCCGCGTCACCGCGTTTTCGGCCGACACCGCGCAGGAAATGAGCCAGTACCTGGACCAGGCATCCGACGACCAGCACC
TGCGCGGGCTGGTACTGGACCTGCGCGGCAATCGCGGCGGGGTGCTGCAGCAGGCGGTGACGGCCAGCGCGCTGGTGCTG
GACCAGGGCGTGGCGGCGATCACCCACGGCCGGGACCCGGAAGCCAACCATGTCTGGGCGGTGCAGGGCGGCGACATGAC
CGGGGGCGTGCCGATCGTGGTGCTGGTGGACGGGCGGACCGCCAGCGCGGCCGAGATCCTGGCCGCCTCGCTGGCCGACC
ACCGGCGCGCCGTGGTGGTGGGCAGCGCCACGCTGGGCAAGGGACTGGTGCAGACGATCGGCCAGATGCCCGACGGTGGT
GAGTTGTTCGTGACCTGGAGCCGCGTCCTGGCGCCGCTGGGCTGGCCGCTGCAGGGGCTGGGCGTCATGCCGCAGGTCTG
CACCAGCCGGGGCGAAAGCGACCTGGAACGGCAGTTGCAGGACCTGGCGGCCGGCCAGGTGGACATGCGCGACGCCGTCC
AGGCGACGCGCGCCACGCGCTATCCCGTGCCGGTGTCGCGCATCCTGGACCTGCGCCGCGCCTGCCCGGCGGCGATCGGC
ACCGATTCCGACCTGGATGCCGCGCGGTCGCTGATCGACAATCCCGCCGAATACCGCGCCGCCCTGTCCGCCATCCCCGA
GGAGAGCCCCTATGCGCCGCAGGCTGAATAA

Upstream 100 bases:

>100_bases
CGACACCGGTGACCGGCGGGCTGCTGTTCGCCCTGGTGGGCGCGAATCCAGCGGCGGCGTCCGGCCCGGCGCGCCGCGCG
CGTGGCACGCGCCCACGCTG

Downstream 100 bases:

>100_bases
CCCGCCGGACGCCGGAGCATGACCGAGGCCCGGCTGCGCACGGGGCTGTGGGCCGCCGCCGTGATCCGGCAGGCGAACCA
GGACGGCCATCCCGCCATGG

Product: carboxy-terminal processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MRAPSVPVPAGPVSAGWIPAPLRGAGRRVTSVILPTRTIAIMLIVIHLMTPVLAPVAARAAGTPAPPPPPRPAPTPGQDT
RSQDTSQILVQADPVPQAGQLDADMTISVVNAALTFLLPRTLESHTPRDFCLWGLNGLSAIDPSLTVVEQRGPEQKGANQ
NGIIQLSLGQEIVLRLPAPPDSDQAGWTDLTVRLMQAAWARSGTVRGAGADGLMQSFFDELFNHMDPYSRYVAPSPATTD
RDTRTGGEAGTGLTLGRDARSILITGVNANGPAWPAGLATGQRLYAVNGRSTRDQTPGTVAQWLLGAPGSTVTVTVGDGR
ARRTVTLRRASVPPETVFAYAAEHMVVIRVTAFSADTAQEMSQYLDQASDDQHLRGLVLDLRGNRGGVLQQAVTASALVL
DQGVAAITHGRDPEANHVWAVQGGDMTGGVPIVVLVDGRTASAAEILAASLADHRRAVVVGSATLGKGLVQTIGQMPDGG
ELFVTWSRVLAPLGWPLQGLGVMPQVCTSRGESDLERQLQDLAAGQVDMRDAVQATRATRYPVPVSRILDLRRACPAAIG
TDSDLDAARSLIDNPAEYRAALSAIPEESPYAPQAE

Sequences:

>Translated_596_residues
MRAPSVPVPAGPVSAGWIPAPLRGAGRRVTSVILPTRTIAIMLIVIHLMTPVLAPVAARAAGTPAPPPPPRPAPTPGQDT
RSQDTSQILVQADPVPQAGQLDADMTISVVNAALTFLLPRTLESHTPRDFCLWGLNGLSAIDPSLTVVEQRGPEQKGANQ
NGIIQLSLGQEIVLRLPAPPDSDQAGWTDLTVRLMQAAWARSGTVRGAGADGLMQSFFDELFNHMDPYSRYVAPSPATTD
RDTRTGGEAGTGLTLGRDARSILITGVNANGPAWPAGLATGQRLYAVNGRSTRDQTPGTVAQWLLGAPGSTVTVTVGDGR
ARRTVTLRRASVPPETVFAYAAEHMVVIRVTAFSADTAQEMSQYLDQASDDQHLRGLVLDLRGNRGGVLQQAVTASALVL
DQGVAAITHGRDPEANHVWAVQGGDMTGGVPIVVLVDGRTASAAEILAASLADHRRAVVVGSATLGKGLVQTIGQMPDGG
ELFVTWSRVLAPLGWPLQGLGVMPQVCTSRGESDLERQLQDLAAGQVDMRDAVQATRATRYPVPVSRILDLRRACPAAIG
TDSDLDAARSLIDNPAEYRAALSAIPEESPYAPQAE
>Mature_596_residues
MRAPSVPVPAGPVSAGWIPAPLRGAGRRVTSVILPTRTIAIMLIVIHLMTPVLAPVAARAAGTPAPPPPPRPAPTPGQDT
RSQDTSQILVQADPVPQAGQLDADMTISVVNAALTFLLPRTLESHTPRDFCLWGLNGLSAIDPSLTVVEQRGPEQKGANQ
NGIIQLSLGQEIVLRLPAPPDSDQAGWTDLTVRLMQAAWARSGTVRGAGADGLMQSFFDELFNHMDPYSRYVAPSPATTD
RDTRTGGEAGTGLTLGRDARSILITGVNANGPAWPAGLATGQRLYAVNGRSTRDQTPGTVAQWLLGAPGSTVTVTVGDGR
ARRTVTLRRASVPPETVFAYAAEHMVVIRVTAFSADTAQEMSQYLDQASDDQHLRGLVLDLRGNRGGVLQQAVTASALVL
DQGVAAITHGRDPEANHVWAVQGGDMTGGVPIVVLVDGRTASAAEILAASLADHRRAVVVGSATLGKGLVQTIGQMPDGG
ELFVTWSRVLAPLGWPLQGLGVMPQVCTSRGESDLERQLQDLAAGQVDMRDAVQATRATRYPVPVSRILDLRRACPAAIG
TDSDLDAARSLIDNPAEYRAALSAIPEESPYAPQAE

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=324, Percent_Identity=29.0123456790123, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 62683; Mature: 62683

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPSVPVPAGPVSAGWIPAPLRGAGRRVTSVILPTRTIAIMLIVIHLMTPVLAPVAARA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGTPAPPPPPRPAPTPGQDTRSQDTSQILVQADPVPQAGQLDADMTISVVNAALTFLLPR
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLESHTPRDFCLWGLNGLSAIDPSLTVVEQRGPEQKGANQNGIIQLSLGQEIVLRLPAPP
HHHCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHCCCCCCCEEEEECCCEEEEECCCCC
DSDQAGWTDLTVRLMQAAWARSGTVRGAGADGLMQSFFDELFNHMDPYSRYVAPSPATTD
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
RDTRTGGEAGTGLTLGRDARSILITGVNANGPAWPAGLATGQRLYAVNGRSTRDQTPGTV
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
AQWLLGAPGSTVTVTVGDGRARRTVTLRRASVPPETVFAYAAEHMVVIRVTAFSADTAQE
HHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEEEEECCCHHHHH
MSQYLDQASDDQHLRGLVLDLRGNRGGVLQQAVTASALVLDQGVAAITHGRDPEANHVWA
HHHHHHCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEE
VQGGDMTGGVPIVVLVDGRTASAAEILAASLADHRRAVVVGSATLGKGLVQTIGQMPDGG
EECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCC
ELFVTWSRVLAPLGWPLQGLGVMPQVCTSRGESDLERQLQDLAAGQVDMRDAVQATRATR
EEEEEHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
YPVPVSRILDLRRACPAAIGTDSDLDAARSLIDNPAEYRAALSAIPEESPYAPQAE
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRAPSVPVPAGPVSAGWIPAPLRGAGRRVTSVILPTRTIAIMLIVIHLMTPVLAPVAARA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGTPAPPPPPRPAPTPGQDTRSQDTSQILVQADPVPQAGQLDADMTISVVNAALTFLLPR
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLESHTPRDFCLWGLNGLSAIDPSLTVVEQRGPEQKGANQNGIIQLSLGQEIVLRLPAPP
HHHCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHCCCCCCCEEEEECCCEEEEECCCCC
DSDQAGWTDLTVRLMQAAWARSGTVRGAGADGLMQSFFDELFNHMDPYSRYVAPSPATTD
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
RDTRTGGEAGTGLTLGRDARSILITGVNANGPAWPAGLATGQRLYAVNGRSTRDQTPGTV
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHH
AQWLLGAPGSTVTVTVGDGRARRTVTLRRASVPPETVFAYAAEHMVVIRVTAFSADTAQE
HHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEEEEECCCHHHHH
MSQYLDQASDDQHLRGLVLDLRGNRGGVLQQAVTASALVLDQGVAAITHGRDPEANHVWA
HHHHHHCCCCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEE
VQGGDMTGGVPIVVLVDGRTASAAEILAASLADHRRAVVVGSATLGKGLVQTIGQMPDGG
EECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCC
ELFVTWSRVLAPLGWPLQGLGVMPQVCTSRGESDLERQLQDLAAGQVDMRDAVQATRATR
EEEEEHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
YPVPVSRILDLRRACPAAIGTDSDLDAARSLIDNPAEYRAALSAIPEESPYAPQAE
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA