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The map label for this gene is rnr [H]

Identifier: 162145883

GI number: 162145883

Start: 47138

End: 49483

Strand: Reverse

Name: rnr [H]

Synonym: GDI_0044

Alternate gene names: 162145883

Gene position: 49483-47138 (Counterclockwise)

Preceding gene: 162145884

Following gene: 162145882

Centisome position: 1.25

GC content: 73.27

Gene sequence:

>2346_bases
ATGGGGGGACGGAACCCGTCCGACCCTCAGCCGACCGCCTGCCCGTCGCCCGACGTTCCGCCGACCGATCCGCGCCCCCC
GGCCCCGCCGCAGCCGGGCGGGGGCCTGCCGGACCGCGAGGCGCTGCGCCGGTTCGTCACCGAGGCCAGCGGCCGTGTCG
GCAAGCGCGAGATCGCACGCGCCTTCAACCTGGGTCCCGAACACAAGGCGGCGCTGCGCGCCATGCTGCGCGAACTGGCG
CTGGAGGGCACGCTGGTCCCGGCCGGCGCCAGGCGCTTCCGCGCGTCCGCCGCCATGCCCGAGGCCGCGTTGGTGCAGGT
GACGGGCACCGACCCGGACGGCGACCCGATCGCCCGCCCCGTGGTGTGGGATGGCGACGGCCCGGCGCCGGTCGTCTTCA
TGCATCCCGAGCAGAAGGGCCGCCCCGCGCTGGCGCCCGGCGAGCGGGTGGTGGCGCGGCTGAAGCGACTCGGCCCCGGC
CGGTACGAAGGCCGCACCCTGCGCCGCCTGACCGATGCGCCGGGCCGCATCGTGGGCGTGTTCCGCCCGACGACCCTGTA
TGACGGCCCTGGGCCGCTAGCCCCGCCCCGCCGGCACGCCGAGGCCGGGCGCCTGGTTCCGGCCGACCGCCGGGCGAAGG
CGGAATGGATCATCCCGGCGGGCGAGACGATGGGCGCCGAAGCCGAGGAGGTCGTCGTGGCCGAGCCGCTGCCGCTGGCG
GGGTCCGGCCTGAAACCCGCGCGGATCGTGGCCCGGCTGGGCCCGATGGGCGATGCGCGGTCGGTCAGCCTGCTGGCGAT
CCACACCCATTCGATTCCCGACCAGTTCCCCGCCGAGGCGCTGTCCGAAGCGGAACGGGCGCGCGGCGTGTCGCCCGAGG
GTCGCGAGGATCTGCGCGACGTACCGCTGATCACCATCGACGGGGAGGATGCCCGGGATTTCGACGACGCGGTCTATGCC
GAACCGGACGGCGACGGATTCCGCCTGATCGTCGCCATTGCGGACGTGGCGCATTACGTCCGCCCCGGATCGGCCCTGGA
CCGCGAGGCGCGGCGGCGGGGCAATTCGGTCTATTTCCCCGACCGGGTGGTGCCGATGCTGCCCGAGGCGCTGTCGAACG
GATGGTGCTCGCTGCGCCCGGGCGAGGATCGGGGCTGCCTGTTCGCCGAGATCTTCATCGACGCGGCGGGGAACAAGACC
CGCCACCGCTTCGGCCGCGGCATCATGCGCAGCGCCGCGCGCCTGACCTACGACCAGGCCCAGGCGATCGTCGGAAACGT
GGAGGAGAGCCAGCAGGAAACCGGCCTGCCGGACGGGCTGATCAACACATTGTTTACGGCGTGGCGCGCACTGTCGACGG
CGCGCGCGCGGCGTGGCACGCTGGATCTCGATGTGCCGGAGCGCGTGGTGCGACTCGACACGTCCGGGCGGATCACCGCC
ATCGAACCCCGCCCCCGTCACGACAGCCATCGCCTGATCGAGGAATTCATGGTGCTGGCCAATGTTGCCGCCGCCGAGGA
ACTGGAACGAAGGCGCCGGCCCTGCCTGTATCGTATCCACGCGCCGCCTTCGCCCGAACGGGCCGAGGCGATGCGCGACA
GCCTGTCGGCCATGGGGTTCGACCTGCCGCCGCCCGGGGCGTTGCGCGCGCGCGACCTGGGCGCGGTGCTGGCGCGCGCC
GCGCAGGGCGAGGCATCCGGCCCCGCCAGCGGCACGCCCGTCAGCGGAACCCTGGTCAGCGAGACGATCCTGCGGGCGCA
GAGCCAGGCCGAATACAGCCCCGACAATATCGGCCATTTCGGCCTGGCGCTGCCGGCCTATGCCCATTTCACCAGCCCGA
TCCGCCGCTATGCCGACCTGCTGGTGCATCGCGCCCTGATCGGGATGGGCACGCAGCCGGCCGACGGCATGCCGGCCGCC
GACGCCGCATGCCTGGACGAGATCGGCGAGCAGGTCAGCACCGCCGAGCGCCGCGCCGCGCTGGCCGAGCGCGAGACGAC
GGAACGCTATGTCGCCGCATGGCTGGCGGACCGGGTCGGGGCGGAATTTTCCGGCCATGTGTCGGGCGTAACCCGGTTCG
GCGCGTTCGTGACATTGACGCAGACCGGCGCCACCGGTCTGGTACCGGTATCGACCCTGCCCGACGATGTCTGGACGCAT
GACGAAAAGACCCAAACCCTGCGTGGCCGCCACGGTGGACTGGCCTTGCGGCTGGGCCAGCCGGTCACGGTACGGCTGGT
CGAGGCGACACCGGTGACCGGCGGGCTGCTGTTCGCCCTGGTGGGCGCGAATCCAGCGGCGGCGTCCGGCCCGGCGCGCC
GCGCGCGTGGCACGCGCCCACGCTGA

Upstream 100 bases:

>100_bases
CGGCCGGCAAGGCAACGGGCAAGACCGCGAAGGGCAAGGCCGAACCCGGCGAGGGTGCCGGGCCCCGCACGCGGCGCACG
GCGACCGAGGCCGGCTGACG

Downstream 100 bases:

>100_bases
TGCGCGCGCCATCCGTTCCCGTTCCGGCGGGCCCCGTTTCGGCGGGCTGGATCCCCGCCCCGCTCCGTGGGGCCGGGCGA
CGGGTCACGTCCGTGATCCT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MGGRNPSDPQPTACPSPDVPPTDPRPPAPPQPGGGLPDREALRRFVTEASGRVGKREIARAFNLGPEHKAALRAMLRELA
LEGTLVPAGARRFRASAAMPEAALVQVTGTDPDGDPIARPVVWDGDGPAPVVFMHPEQKGRPALAPGERVVARLKRLGPG
RYEGRTLRRLTDAPGRIVGVFRPTTLYDGPGPLAPPRRHAEAGRLVPADRRAKAEWIIPAGETMGAEAEEVVVAEPLPLA
GSGLKPARIVARLGPMGDARSVSLLAIHTHSIPDQFPAEALSEAERARGVSPEGREDLRDVPLITIDGEDARDFDDAVYA
EPDGDGFRLIVAIADVAHYVRPGSALDREARRRGNSVYFPDRVVPMLPEALSNGWCSLRPGEDRGCLFAEIFIDAAGNKT
RHRFGRGIMRSAARLTYDQAQAIVGNVEESQQETGLPDGLINTLFTAWRALSTARARRGTLDLDVPERVVRLDTSGRITA
IEPRPRHDSHRLIEEFMVLANVAAAEELERRRRPCLYRIHAPPSPERAEAMRDSLSAMGFDLPPPGALRARDLGAVLARA
AQGEASGPASGTPVSGTLVSETILRAQSQAEYSPDNIGHFGLALPAYAHFTSPIRRYADLLVHRALIGMGTQPADGMPAA
DAACLDEIGEQVSTAERRAALAERETTERYVAAWLADRVGAEFSGHVSGVTRFGAFVTLTQTGATGLVPVSTLPDDVWTH
DEKTQTLRGRHGGLALRLGQPVTVRLVEATPVTGGLLFALVGANPAAASGPARRARGTRPR

Sequences:

>Translated_781_residues
MGGRNPSDPQPTACPSPDVPPTDPRPPAPPQPGGGLPDREALRRFVTEASGRVGKREIARAFNLGPEHKAALRAMLRELA
LEGTLVPAGARRFRASAAMPEAALVQVTGTDPDGDPIARPVVWDGDGPAPVVFMHPEQKGRPALAPGERVVARLKRLGPG
RYEGRTLRRLTDAPGRIVGVFRPTTLYDGPGPLAPPRRHAEAGRLVPADRRAKAEWIIPAGETMGAEAEEVVVAEPLPLA
GSGLKPARIVARLGPMGDARSVSLLAIHTHSIPDQFPAEALSEAERARGVSPEGREDLRDVPLITIDGEDARDFDDAVYA
EPDGDGFRLIVAIADVAHYVRPGSALDREARRRGNSVYFPDRVVPMLPEALSNGWCSLRPGEDRGCLFAEIFIDAAGNKT
RHRFGRGIMRSAARLTYDQAQAIVGNVEESQQETGLPDGLINTLFTAWRALSTARARRGTLDLDVPERVVRLDTSGRITA
IEPRPRHDSHRLIEEFMVLANVAAAEELERRRRPCLYRIHAPPSPERAEAMRDSLSAMGFDLPPPGALRARDLGAVLARA
AQGEASGPASGTPVSGTLVSETILRAQSQAEYSPDNIGHFGLALPAYAHFTSPIRRYADLLVHRALIGMGTQPADGMPAA
DAACLDEIGEQVSTAERRAALAERETTERYVAAWLADRVGAEFSGHVSGVTRFGAFVTLTQTGATGLVPVSTLPDDVWTH
DEKTQTLRGRHGGLALRLGQPVTVRLVEATPVTGGLLFALVGANPAAASGPARRARGTRPR
>Mature_780_residues
GGRNPSDPQPTACPSPDVPPTDPRPPAPPQPGGGLPDREALRRFVTEASGRVGKREIARAFNLGPEHKAALRAMLRELAL
EGTLVPAGARRFRASAAMPEAALVQVTGTDPDGDPIARPVVWDGDGPAPVVFMHPEQKGRPALAPGERVVARLKRLGPGR
YEGRTLRRLTDAPGRIVGVFRPTTLYDGPGPLAPPRRHAEAGRLVPADRRAKAEWIIPAGETMGAEAEEVVVAEPLPLAG
SGLKPARIVARLGPMGDARSVSLLAIHTHSIPDQFPAEALSEAERARGVSPEGREDLRDVPLITIDGEDARDFDDAVYAE
PDGDGFRLIVAIADVAHYVRPGSALDREARRRGNSVYFPDRVVPMLPEALSNGWCSLRPGEDRGCLFAEIFIDAAGNKTR
HRFGRGIMRSAARLTYDQAQAIVGNVEESQQETGLPDGLINTLFTAWRALSTARARRGTLDLDVPERVVRLDTSGRITAI
EPRPRHDSHRLIEEFMVLANVAAAEELERRRRPCLYRIHAPPSPERAEAMRDSLSAMGFDLPPPGALRARDLGAVLARAA
QGEASGPASGTPVSGTLVSETILRAQSQAEYSPDNIGHFGLALPAYAHFTSPIRRYADLLVHRALIGMGTQPADGMPAAD
AACLDEIGEQVSTAERRAALAERETTERYVAAWLADRVGAEFSGHVSGVTRFGAFVTLTQTGATGLVPVSTLPDDVWTHD
EKTQTLRGRHGGLALRLGQPVTVRLVEATPVTGGLLFALVGANPAAASGPARRARGTRPR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=557, Percent_Identity=28.0071813285458, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI190014623, Length=557, Percent_Identity=28.0071813285458, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI134288890, Length=352, Percent_Identity=33.5227272727273, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI219521928, Length=553, Percent_Identity=27.3056057866184, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI19115966, Length=553, Percent_Identity=27.3056057866184, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI156105693, Length=134, Percent_Identity=36.5671641791045, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI156105695, Length=134, Percent_Identity=36.5671641791045, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI87082383, Length=751, Percent_Identity=36.0852197070573, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787542, Length=420, Percent_Identity=31.1904761904762, Blast_Score=161, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI212645896, Length=604, Percent_Identity=28.476821192053, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17553506, Length=518, Percent_Identity=28.3783783783784, Blast_Score=163, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=436, Percent_Identity=31.651376146789, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24649634, Length=622, Percent_Identity=28.2958199356913, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24654592, Length=351, Percent_Identity=32.1937321937322, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI19922976, Length=351, Percent_Identity=32.1937321937322, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24654597, Length=351, Percent_Identity=32.1937321937322, Blast_Score=164, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 83616; Mature: 83485

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRNPSDPQPTACPSPDVPPTDPRPPAPPQPGGGLPDREALRRFVTEASGRVGKREIAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
AFNLGPEHKAALRAMLRELALEGTLVPAGARRFRASAAMPEAALVQVTGTDPDGDPIARP
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
VVWDGDGPAPVVFMHPEQKGRPALAPGERVVARLKRLGPGRYEGRTLRRLTDAPGRIVGV
EEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEE
FRPTTLYDGPGPLAPPRRHAEAGRLVPADRRAKAEWIIPAGETMGAEAEEVVVAEPLPLA
ECCCEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCC
GSGLKPARIVARLGPMGDARSVSLLAIHTHSIPDQFPAEALSEAERARGVSPEGREDLRD
CCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
VPLITIDGEDARDFDDAVYAEPDGDGFRLIVAIADVAHYVRPGSALDREARRRGNSVYFP
CCEEEECCCCCCCCCCCEEECCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
DRVVPMLPEALSNGWCSLRPGEDRGCLFAEIFIDAAGNKTRHRFGRGIMRSAARLTYDQA
CCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
QAIVGNVEESQQETGLPDGLINTLFTAWRALSTARARRGTLDLDVPERVVRLDTSGRITA
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCEEE
IEPRPRHDSHRLIEEFMVLANVAAAEELERRRRPCLYRIHAPPSPERAEAMRDSLSAMGF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCC
DLPPPGALRARDLGAVLARAAQGEASGPASGTPVSGTLVSETILRAQSQAEYSPDNIGHF
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
GLALPAYAHFTSPIRRYADLLVHRALIGMGTQPADGMPAADAACLDEIGEQVSTAERRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAERETTERYVAAWLADRVGAEFSGHVSGVTRFGAFVTLTQTGATGLVPVSTLPDDVWTH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEEEEECCCCCEEECCCCCHHHHCC
DEKTQTLRGRHGGLALRLGQPVTVRLVEATPVTGGLLFALVGANPAAASGPARRARGTRP
CCHHHHHCCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHCCCCCC
R
C
>Mature Secondary Structure 
GGRNPSDPQPTACPSPDVPPTDPRPPAPPQPGGGLPDREALRRFVTEASGRVGKREIAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
AFNLGPEHKAALRAMLRELALEGTLVPAGARRFRASAAMPEAALVQVTGTDPDGDPIARP
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
VVWDGDGPAPVVFMHPEQKGRPALAPGERVVARLKRLGPGRYEGRTLRRLTDAPGRIVGV
EEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEE
FRPTTLYDGPGPLAPPRRHAEAGRLVPADRRAKAEWIIPAGETMGAEAEEVVVAEPLPLA
ECCCEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCC
GSGLKPARIVARLGPMGDARSVSLLAIHTHSIPDQFPAEALSEAERARGVSPEGREDLRD
CCCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
VPLITIDGEDARDFDDAVYAEPDGDGFRLIVAIADVAHYVRPGSALDREARRRGNSVYFP
CCEEEECCCCCCCCCCCEEECCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
DRVVPMLPEALSNGWCSLRPGEDRGCLFAEIFIDAAGNKTRHRFGRGIMRSAARLTYDQA
CCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
QAIVGNVEESQQETGLPDGLINTLFTAWRALSTARARRGTLDLDVPERVVRLDTSGRITA
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCEEE
IEPRPRHDSHRLIEEFMVLANVAAAEELERRRRPCLYRIHAPPSPERAEAMRDSLSAMGF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCC
DLPPPGALRARDLGAVLARAAQGEASGPASGTPVSGTLVSETILRAQSQAEYSPDNIGHF
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCH
GLALPAYAHFTSPIRRYADLLVHRALIGMGTQPADGMPAADAACLDEIGEQVSTAERRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAERETTERYVAAWLADRVGAEFSGHVSGVTRFGAFVTLTQTGATGLVPVSTLPDDVWTH
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEEEEECCCCCEEECCCCCHHHHCC
DEKTQTLRGRHGGLALRLGQPVTVRLVEATPVTGGLLFALVGANPAAASGPARRARGTRP
CCHHHHHCCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]