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The map label for this gene is ans [H]

Identifier: 161870536

GI number: 161870536

Start: 1631376

End: 1632371

Strand: Reverse

Name: ans [H]

Synonym: NMCC_1601

Alternate gene names: 161870536

Gene position: 1632371-1631376 (Counterclockwise)

Preceding gene: 161870537

Following gene: 161870535

Centisome position: 75.8

GC content: 59.04

Gene sequence:

>996_bases
ATGAGCCATGAAACAGAAAATTTTTGTCCTTTATACCGGCGGCACCATCGGCATGACGCAAGCAGCGAAGGCCTGCGCCC
CGATACCGCGCTGGTCGGGCAGGCACTCGCGCCGTTTTCAAACGGCATGGATTTCGATTGGCACGTTTGTGGGACGCTGA
TTGATTCTTCCGCCGTCCAACTGCAAAACTGGTGCGCTTGGCTGGACATCATTGCCACCGCGCTGCCGCAGTACGACGGC
GTTTTGGTGCTGCACGGTACGGACACGCTCGCCTATACCGCCAATCTGTTCGCCCTCGCGCTGCAGGGTTTGGACAAGCC
AATCGTCCTGACCGGTTCCCAATGGCCGTACAACGCCGTGGGCAGCGACGCGCCGCGCAATCTGGCGACTGCCGTTGCCG
CATTCCCACTCGGATTGAAGCAGACGCTTATTGCCTTTGACGGCAAACTTTATCCCGCCGTCGGCAGCAGCAAAGTCAGC
ACCGAAACCGCCGCCGGTTTCGACAATCCGCATTTCGGCGCACTGGCGGAGTGGGACGAAACCCAGGGCTGGCACAATGT
CCGCATCCCGAATCAGGACACGGCAGATGTTTCAGACGGCCTCAAAATCCGTTATCCCGACCCGCAGGCAAAAATCGCCG
TCCGCACGCTTATCCCCGGCTTTGCCGTCCAAGAACTTGCCGACGGACTCGGACAGCTTCCCGCCCACGCCCTTATCCTG
CAAAGTTACGGACACGGCAACACGCCCGCAGACGAAGGCTTTATCCGCGCTGTCCGAGACTTCACGCGGCAAGGAAAATT
GTTGCTCAACATCAGCCAAGTCCGACAAGGCAGAACTGCCGCCGTTTACGCGCAAGGCAATGCGTTCCGCAACTCGGGCA
TCATCAACGGCGGCAAATGCAACCTCGAAACCGCCACCGCGCTGATGACCCTCGCCGTATCGCAAGGCTGGGGCGCGGAA
GATGTAGAAAAAGAGTTGGCAAGACTGAAGTTATAG

Upstream 100 bases:

>100_bases
CGGAAAAGGCAGCGAAAAAAGCGGCACAGAAGCAGCAGTAAATCAGATTTTCGACCGTCCGGACGCATTTCGCGTTTCAG
GCGGTCTTTGCATTTTCAGG

Downstream 100 bases:

>100_bases
CGGATTGAAATGGCAATGACGGGGCGTTGACCGCGCCTTATGCGCCGCCCGTACACGGCATCCCTTGCCGCCCTGCCTTA
TTTTTATGTGAACCTGCCGC

Product: L-asparaginase

Products: NA

Alternate protein names: L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSHETENFCPLYRRHHRHDASSEGLRPDTALVGQALAPFSNGMDFDWHVCGTLIDSSAVQLQNWCAWLDIIATALPQYDG
VLVLHGTDTLAYTANLFALALQGLDKPIVLTGSQWPYNAVGSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVS
TETAAGFDNPHFGALAEWDETQGWHNVRIPNQDTADVSDGLKIRYPDPQAKIAVRTLIPGFAVQELADGLGQLPAHALIL
QSYGHGNTPADEGFIRAVRDFTRQGKLLLNISQVRQGRTAAVYAQGNAFRNSGIINGGKCNLETATALMTLAVSQGWGAE
DVEKELARLKL

Sequences:

>Translated_331_residues
MSHETENFCPLYRRHHRHDASSEGLRPDTALVGQALAPFSNGMDFDWHVCGTLIDSSAVQLQNWCAWLDIIATALPQYDG
VLVLHGTDTLAYTANLFALALQGLDKPIVLTGSQWPYNAVGSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVS
TETAAGFDNPHFGALAEWDETQGWHNVRIPNQDTADVSDGLKIRYPDPQAKIAVRTLIPGFAVQELADGLGQLPAHALIL
QSYGHGNTPADEGFIRAVRDFTRQGKLLLNISQVRQGRTAAVYAQGNAFRNSGIINGGKCNLETATALMTLAVSQGWGAE
DVEKELARLKL
>Mature_330_residues
SHETENFCPLYRRHHRHDASSEGLRPDTALVGQALAPFSNGMDFDWHVCGTLIDSSAVQLQNWCAWLDIIATALPQYDGV
LVLHGTDTLAYTANLFALALQGLDKPIVLTGSQWPYNAVGSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVST
ETAAGFDNPHFGALAEWDETQGWHNVRIPNQDTADVSDGLKIRYPDPQAKIAVRTLIPGFAVQELADGLGQLPAHALILQ
SYGHGNTPADEGFIRAVRDFTRQGKLLLNISQVRQGRTAAVYAQGNAFRNSGIINGGKCNLETATALMTLAVSQGWGAED
VEKELARLKL

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=322, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1788065, Length=289, Percent_Identity=31.1418685121107, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17558278, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193207374, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193207372, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17558280, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24645530, Length=307, Percent_Identity=25.4071661237785, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639609, Length=290, Percent_Identity=26.551724137931, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006033
- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 35715; Mature: 35583

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00917 ASN_GLN_ASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHETENFCPLYRRHHRHDASSEGLRPDTALVGQALAPFSNGMDFDWHVCGTLIDSSAVQ
CCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
LQNWCAWLDIIATALPQYDGVLVLHGTDTLAYTANLFALALQGLDKPIVLTGSQWPYNAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
GSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVSTETAAGFDNPHFGALAEWDE
CCCCCHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHH
TQGWHNVRIPNQDTADVSDGLKIRYPDPQAKIAVRTLIPGFAVQELADGLGQLPAHALIL
CCCEEEEECCCCCCCCCCCCCEEECCCCCHHEEHHHHCCCHHHHHHHHHHHCCCHHHHHH
QSYGHGNTPADEGFIRAVRDFTRQGKLLLNISQVRQGRTAAVYAQGNAFRNSGIINGGKC
HHCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
NLETATALMTLAVSQGWGAEDVEKELARLKL
CHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SHETENFCPLYRRHHRHDASSEGLRPDTALVGQALAPFSNGMDFDWHVCGTLIDSSAVQ
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
LQNWCAWLDIIATALPQYDGVLVLHGTDTLAYTANLFALALQGLDKPIVLTGSQWPYNAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
GSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVSTETAAGFDNPHFGALAEWDE
CCCCCHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHH
TQGWHNVRIPNQDTADVSDGLKIRYPDPQAKIAVRTLIPGFAVQELADGLGQLPAHALIL
CCCEEEEECCCCCCCCCCCCCEEECCCCCHHEEHHHHCCCHHHHHHHHHHHCCCHHHHHH
QSYGHGNTPADEGFIRAVRDFTRQGKLLLNISQVRQGRTAAVYAQGNAFRNSGIINGGKC
HHCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
NLETATALMTLAVSQGWGAEDVEKELARLKL
CHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]