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The map label for this gene is pilE1 [H]

Identifier: 161870477

GI number: 161870477

Start: 1562053

End: 1562379

Strand: Direct

Name: pilE1 [H]

Synonym: NMCC_1533

Alternate gene names: 161870477

Gene position: 1562053-1562379 (Clockwise)

Preceding gene: 161870473

Following gene: 161870478

Centisome position: 72.54

GC content: 54.13

Gene sequence:

>327_bases
GTGGGAATGACGGGATTTAATGATGCCGCCGGCGTGGCATCCTCCCCCTCCGACATCAAAGGCAAATATGTTCAAAGCGT
TGAAGTCAAAAACGGCGTCATTACCGCCACAATGCTTTCAAGCGGCGTAAACAACGAAATCAAAGGCAAAAAACTCTCCC
TGTGGGCCACGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCGACGCCCCCAACGCCAGCGCC
GACGCCGTTAACAAAGTCACCGGCAACGAAATCGACACCAAGCACCTGCCGTCAACAGCACCGACAAGAAAATCGACACC
AAACTAG

Upstream 100 bases:

>100_bases
GTATGCTACCGCATACTGGCCTTTTTCTGTTAGGGAAAGTTGCACTTCAAATGCGAATCCGCCGGTTTCTTGAGATTTTG
CGTTCTAGATTCCCACTTTC

Downstream 100 bases:

>100_bases
AGAAACCTTTTTACCCGATAAGTTTCCGCACCGACGAGGCTGGATTCCCGCCTGCGCGGGAATGACGGCGGAGCGGTTTC
TGTTTTTTCCGATAAATTCC

Product: pilS cassette

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MGMTGFNDAAGVASSPSDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWATRQDGSVKWFCGQPVTRDAPNASA
DAVNKVTGNEIDTKHLPSTAPTRKSTPN

Sequences:

>Translated_108_residues
MGMTGFNDAAGVASSPSDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWATRQDGSVKWFCGQPVTRDAPNASA
DAVNKVTGNEIDTKHLPSTAPTRKSTPN
>Mature_107_residues
GMTGFNDAAGVASSPSDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWATRQDGSVKWFCGQPVTRDAPNASAD
AVNKVTGNEIDTKHLPSTAPTRKSTPN

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 11337; Mature: 11206

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMTGFNDAAGVASSPSDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWATRQD
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEECCC
GSVKWFCGQPVTRDAPNASADAVNKVTGNEIDTKHLPSTAPTRKSTPN
CCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GMTGFNDAAGVASSPSDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWATRQD
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEECCC
GSVKWFCGQPVTRDAPNASADAVNKVTGNEIDTKHLPSTAPTRKSTPN
CCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]