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The map label for this gene is ldcA [H]

Identifier: 161870473

GI number: 161870473

Start: 1556710

End: 1557894

Strand: Direct

Name: ldcA [H]

Synonym: NMCC_1529

Alternate gene names: 161870473

Gene position: 1556710-1557894 (Clockwise)

Preceding gene: 161870472

Following gene: 161870477

Centisome position: 72.29

GC content: 57.3

Gene sequence:

>1185_bases
ATGACCGAACCGACCTCCCGCCGTCGTTTTCTGAAAACCTGCACCGCCGCCGCCGGCGCGGGACTGCTTCAGGCTTGCGG
CACATCCGCCACATCCGTTCCGCCCCTTCCCTCTTCCCATTCTGTTGTGAAAGCCCGAACCGTGCCTCTCCAAACGCCAC
GCCGTCAAAGTTCGGACGGCAACCTTCTGCGCGTTGTCGCTTCGTCAGGCTTTGCCGAAGACACCAACCGCGTCAACACA
GCCTTAACCCGCCTTTACAATGCCGGTTTTACCGTAACCAACCAACAGGCGGGCAGCCGCCGCTTCCAACGGTTTGCTGG
TACGGACGCACAACGTGTCGCCGATTTCCAAGAGGTCGCTTCCGGCCGCGTCGCCACGCCTAAAGTGCTGATGGGCTTGC
GCGGCGGTTACGGTGCGGCGCGGATTCTGCCGCATATCGATTTTGCTTCGCTCGGCGCAAGGATGCGCGAACACGGCACG
CTGTTTTTCGGATTCAGCGACGTATGCGCCGTCCAGCTGGCATTGTTGGCAAAAGGCAATATGATGAGTTTTGCCGGCCC
GATGGCTTATAGCGATTTTGGCAAACCCGCCCCCGGTGCGTTTACGATGGATGCCTTTATCAAGGGTGCAACCCAAAACC
GCCTGACCGTTGATGTTCCTTATATCCAACGCGCCGATGTCGAAACCGAAGGCATATTGTGGGGCGGCAACTTAAGCGTC
CTCGCCTCGCTCGCCGGCACGCCTTATATGCCCGACATCGACGGCGGCATTTTGTTCCTCGAAGATGTCGGCGAACAGCC
CTACCGCATCGAACGTATGCTCAATACGCTGTATCTTTCGGGTATTTTGAAGAAACAGCGCGCCATCGTGTTCGGCAATT
TCCGTATGGAAAAAATTCGAGATGTCTATGATCCGTCTTATGATTTTTCCGCCGTTGCCAACCATGTTTCGCGCACGGCG
AAAATCCCCGTGCTGACGGGCTTTCCCTTCGGGCACATTGCCGACAAAATCACTTTCCCTCTGGGCGCGCACGCCCGAAT
CCGTATGAACGGAAACAGCGGTTATTCGGTCGCGTTTGAAGGCTACCCCACACTCGATGCGTCCGCCCTGACTTTGGATA
CCCTGCTCCCACCGCCGGATTTGCCCATCTTCCCCGAAAGCGGTGTTGCCGATATTTCGGAATAA

Upstream 100 bases:

>100_bases
CCGAAAACACGGTATGACCCTGCCGCAAGATTGGACGGAACAGCTTAAAAAGCTGCTTTAAGCCCGCCGATGCCGTCTGA
AACCGTATGAAAGGGAAATT

Downstream 100 bases:

>100_bases
ACCCGCAAACGGACAAATGCCGTCTGAAGCCTTCAGACGGCATTTCCCAAGACGGCGGCAGATTACAGCAATGCCCGAAT
ATCGGCTTCGATTTCTTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDGNLLRVVASSGFAEDTNRVNT
ALTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRVADFQEVASGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGT
LFFGFSDVCAVQLALLAKGNMMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSV
LASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILKKQRAIVFGNFRMEKIRDVYDPSYDFSAVANHVSRTA
KIPVLTGFPFGHIADKITFPLGAHARIRMNGNSGYSVAFEGYPTLDASALTLDTLLPPPDLPIFPESGVADISE

Sequences:

>Translated_394_residues
MTEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDGNLLRVVASSGFAEDTNRVNT
ALTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRVADFQEVASGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGT
LFFGFSDVCAVQLALLAKGNMMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSV
LASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILKKQRAIVFGNFRMEKIRDVYDPSYDFSAVANHVSRTA
KIPVLTGFPFGHIADKITFPLGAHARIRMNGNSGYSVAFEGYPTLDASALTLDTLLPPPDLPIFPESGVADISE
>Mature_393_residues
TEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDGNLLRVVASSGFAEDTNRVNTA
LTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRVADFQEVASGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGTL
FFGFSDVCAVQLALLAKGNMMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSVL
ASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILKKQRAIVFGNFRMEKIRDVYDPSYDFSAVANHVSRTAK
IPVLTGFPFGHIADKITFPLGAHARIRMNGNSGYSVAFEGYPTLDASALTLDTLLPPPDLPIFPESGVADISE

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=306, Percent_Identity=40.1960784313725, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 42411; Mature: 42280

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDG
CCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
NLLRVVASSGFAEDTNRVNTALTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRVADFQEVA
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHH
SGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGTLFFGFSDVCAVQLALLAKGN
CCCCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCC
MMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSV
CCCCCCCCCHHHCCCCCCCCEEHHHHHCCCCCCCEEEECCCCEECCCCCCCEEECCCHHH
LASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILKKQRAIVFGNFRMEKIR
HHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
DVYDPSYDFSAVANHVSRTAKIPVLTGFPFGHIADKITFPLGAHARIRMNGNSGYSVAFE
HHCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEC
GYPTLDASALTLDTLLPPPDLPIFPESGVADISE
CCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDG
CCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
NLLRVVASSGFAEDTNRVNTALTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRVADFQEVA
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHH
SGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGTLFFGFSDVCAVQLALLAKGN
CCCCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCC
MMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRADVETEGILWGGNLSV
CCCCCCCCCHHHCCCCCCCCEEHHHHHCCCCCCCEEEECCCCEECCCCCCCEEECCCHHH
LASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILKKQRAIVFGNFRMEKIR
HHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
DVYDPSYDFSAVANHVSRTAKIPVLTGFPFGHIADKITFPLGAHARIRMNGNSGYSVAFE
HHCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEC
GYPTLDASALTLDTLLPPPDLPIFPESGVADISE
CCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]