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The map label for this gene is trkA [H]

Identifier: 161870465

GI number: 161870465

Start: 1547092

End: 1548546

Strand: Direct

Name: trkA [H]

Synonym: NMCC_1520

Alternate gene names: 161870465

Gene position: 1547092-1548546 (Clockwise)

Preceding gene: 161870464

Following gene: 161870467

Centisome position: 71.84

GC content: 58.14

Gene sequence:

>1455_bases
TTGCGGTACAATCCACCATTTCATCACTCGGCGACCCACACCGTGAAAATCCTCATTTTAGGCAACGGACAGGTAGGTTC
TACCGTCGCACAAAACCTTGCCGCCATACCCAACAACGACGTAACCGTTATCGACATCGACGAAAAAGCATTGCAGGAAA
CAGGCAGCCGCCTCGATGTCCAAACCGTTTTCGGCAACGGCGCATCCCCCTTCACATTAGAACGCGCCGGCGCGGAAGAT
GCCGACTTGCTGCTCGCGCTCTCCCGCAGCGACGAAACCAACATCGTCGCCTGCAAAGTTGCCGCCGACCTGTTCAACAT
CCCCGGCCGCATCGCGCGCGTCCGTTCCAGCGAATACCTCGAATACCTCAGCCCCAAGCTCGAAAACAACGAAAACGGCA
GCCTTTCCATATTCGGCATAACCGAAACCATCAGCCCCGAACAGCTCGTTACCGAACAGCTTGCCGGCCTGATAGACTGC
CCGGGCGCATTGCAGGTTTTACGTTTTGCAGACGACCGCGTGCGGATGGTCATCATACAGGCGCGGCGCGGCGGACTGCT
TGTCGGACGCAGCATTGCCGACATCGCCCAAGATTTGCCCGACGGGGCCGACTGCCAAATCTGCGCCGTTTACCGCAACA
ACCGCCTCATCGTCCCCGCGCCGCAAACCGTCATCATCGAAGGCGACGAAATCCTATTTGCCGCCGCCGCCGAAAACATC
GGCGCGGTCATACCCGAATTGCGCCCCAAAGAAACCAGCACCCGCCGCATCATGATTGCCGGCGGCGGCAACATCGGCTA
CCGCCTCGCCAAACAGCTCGAACACGCATACAACGTCAAAATCATCGAATGTCGGCCGCGCCGTGCCGAATGGATAGCCG
AAAACCTCGACAACACCCTCGTCCTGCAAGGTTCGGCAACCGACGAAACCCTGCTCGACAACGAATACATCGACGAAATC
GACGTATTTTGCGCCCTGACCAACGACGACGAAAGCAACATTATGTCCGCCCTTTTGGCGAAAAACCTCGGCGCGAAGCG
CGTCATCGGCATCGTCAACCGCTCAAGCTACGTCGATTTGCTCGAAGGCAACAAAATCGACATCGTCGTCTCCCCCCACC
TCATCACCATCGGCTCGATACTCGCCCACATCCGGCGCGGCGACATCGTTGCCGTCCACCCCATCCGGCGCGGCACGGCG
GAAGCCATCGAAGTCGTCGCACACGGCGACAAAAAAACTTCCGCCATCATCGGCAGGCGCATCAGCGGCATCAAATGGCC
CGAAGGCTGCCACATTGCCGCCGTCGTCCGCGCCGGAACCGGCGAAACCATTATGGGACACCATACCGAAACCGTCATCC
AAGACGGCGATCACATCATCTTTTTCGTCTCGCGCCGGCGCATCCTGAACGAACTGGAAAAACTCATCCAAGTCAAAATG
GGCTTTTTCGGATAA

Upstream 100 bases:

>100_bases
CCCCAATGGCAGGCGAAAATCGGCATCATCCCCGTCGAATCTTGAGGCGCCATGCCGTCTGAACACAAAATCTGCTTTCA
GACGGCATTTCCGCCCCTGG

Downstream 100 bases:

>100_bases
ACCGCCCCATTCCGGACACATTGCCGCCAAGCGGTATGGAAGCGGAATAATGGTAGGTGGGCTTCAGACGGCATCCGCCC
TCCCCGTCATTCCCGCGTAA

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MRYNPPFHHSATHTVKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDVQTVFGNGASPFTLERAGAED
ADLLLALSRSDETNIVACKVAADLFNIPGRIARVRSSEYLEYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDC
PGALQVLRFADDRVRMVIIQARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEILFAAAAENI
GAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAEWIAENLDNTLVLQGSATDETLLDNEYIDEI
DVFCALTNDDESNIMSALLAKNLGAKRVIGIVNRSSYVDLLEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTA
EAIEVVAHGDKKTSAIIGRRISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVSRRRILNELEKLIQVKM
GFFG

Sequences:

>Translated_484_residues
MRYNPPFHHSATHTVKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDVQTVFGNGASPFTLERAGAED
ADLLLALSRSDETNIVACKVAADLFNIPGRIARVRSSEYLEYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDC
PGALQVLRFADDRVRMVIIQARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEILFAAAAENI
GAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAEWIAENLDNTLVLQGSATDETLLDNEYIDEI
DVFCALTNDDESNIMSALLAKNLGAKRVIGIVNRSSYVDLLEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTA
EAIEVVAHGDKKTSAIIGRRISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVSRRRILNELEKLIQVKM
GFFG
>Mature_484_residues
MRYNPPFHHSATHTVKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDVQTVFGNGASPFTLERAGAED
ADLLLALSRSDETNIVACKVAADLFNIPGRIARVRSSEYLEYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDC
PGALQVLRFADDRVRMVIIQARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEILFAAAAENI
GAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAEWIAENLDNTLVLQGSATDETLLDNEYIDEI
DVFCALTNDDESNIMSALLAKNLGAKRVIGIVNRSSYVDLLEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTA
EAIEVVAHGDKKTSAIIGRRISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVSRRRILNELEKLIQVKM
GFFG

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=469, Percent_Identity=44.9893390191898, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 52716; Mature: 52716

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNPPFHHSATHTVKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDV
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCCEEEE
QTVFGNGASPFTLERAGAEDADLLLALSRSDETNIVACKVAADLFNIPGRIARVRSSEYL
EEEECCCCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHH
EYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDCPGALQVLRFADDRVRMVIIQ
HHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEE
ARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEILFAAAAENI
ECCCCEEECCHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCEEEEECCCEEEEECCCCH
GAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAEWIAENLDNTL
HHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCCCCEE
VLQGSATDETLLDNEYIDEIDVFCALTNDDESNIMSALLAKNLGAKRVIGIVNRSSYVDL
EEECCCCCCHHCCCHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
LEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTAEAIEVVAHGDKKTSAIIGRR
ECCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEECCCCHHHHHHHHH
ISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVSRRRILNELEKLIQVKM
HCCCCCCCCCEEEEEEECCCCCEEECCCCHHHEECCCEEEEEEHHHHHHHHHHHHHHHHH
GFFG
CCCC
>Mature Secondary Structure
MRYNPPFHHSATHTVKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDV
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHCCCEEEE
QTVFGNGASPFTLERAGAEDADLLLALSRSDETNIVACKVAADLFNIPGRIARVRSSEYL
EEEECCCCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHH
EYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDCPGALQVLRFADDRVRMVIIQ
HHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEE
ARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEILFAAAAENI
ECCCCEEECCHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCEEEEECCCEEEEECCCCH
GAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAEWIAENLDNTL
HHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCCCCEE
VLQGSATDETLLDNEYIDEIDVFCALTNDDESNIMSALLAKNLGAKRVIGIVNRSSYVDL
EEECCCCCCHHCCCHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEE
LEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTAEAIEVVAHGDKKTSAIIGRR
ECCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEECCCCHHHHHHHHH
ISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVSRRRILNELEKLIQVKM
HCCCCCCCCCEEEEEEECCCCCEEECCCCHHHEECCCEEEEEEHHHHHHHHHHHHHHHHH
GFFG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]