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The map label for this gene is efp

Identifier: 161869849

GI number: 161869849

Start: 882265

End: 882825

Strand: Direct

Name: efp

Synonym: NMCC_0880

Alternate gene names: 161869849

Gene position: 882265-882825 (Clockwise)

Preceding gene: 161869848

Following gene: 161869855

Centisome position: 40.97

GC content: 51.34

Gene sequence:

>561_bases
ATGAAAACAGCACAAGAACTGCGCGCCGGCAATGTATTTATGGTCGGCAACGATCCTATGGTCGTTCAAAAAACCGAATA
CATCAAAGGCGGCCGCTCTTCCGCCAAAGTCAGCATGAAACTGAAAAACCTGCTGACCGGCGCGGCTTCCGAAACCATTT
ACAAAGCCGACGACAAATTCGACGTGGTCATCCTGTCCCGCAAGAACTGTACGTACAGCTACTTTGCCGACCCGATGTAT
GTCTTTATGGACGAAGAATTCAACCAATACGAAATCGAAGCCGACAACATCGGCGACGCGTTGAAATTCATCGTTGACGG
TATGGAAGACCAATGCGAAGTTACCTTCTACGAAGGCAACCCCATCTCCGTAGAACTGCCTACCATCATCGTACGCGAAG
TCGAGTACACCGAGCCTGCTGTCAAAGGCGACACTTCCGGCAAAGTGATGAAAACCGCGCGTCTGGTCGGCGGCACCGAA
ATCCAAGTGATGTCTTACATCGAAAACGGCGACAAAGTCGAAATCGATACCCGCACCGGCGAATTCCGCAAACGCGCCTG
A

Upstream 100 bases:

>100_bases
GCCGTCCGCATCCGAAAAACTCGCCGCCTTTGTTTCAAAGCATCAAAAAATACGCTAGAATAGCGCGTTTTACGACAACC
GATTTGATTGGAAAATCACA

Downstream 100 bases:

>100_bases
TATCCTACTTGAAAAATGCCGTCTGAAAGGCTTTCAGACGGCATTTTTTTATCTTCGCCCCAAGTTTGGATTGAAGTAGA
TGTTTTTTTCGTAAACGACA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKFDVVILSRKNCTYSYFADPMY
VFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTE
IQVMSYIENGDKVEIDTRTGEFRKRA

Sequences:

>Translated_186_residues
MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKFDVVILSRKNCTYSYFADPMY
VFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTE
IQVMSYIENGDKVEIDTRTGEFRKRA
>Mature_186_residues
MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKFDVVILSRKNCTYSYFADPMY
VFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTE
IQVMSYIENGDKVEIDTRTGEFRKRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=34.9726775956284, Blast_Score=114, Evalue=3e-27,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NEIG1 (Q5F856)

Other databases:

- EMBL:   AE004969
- RefSeq:   YP_208043.1
- ProteinModelPortal:   Q5F856
- SMR:   Q5F856
- STRING:   Q5F856
- EnsemblBacteria:   EBNEIT00000002801
- GeneID:   3281711
- GenomeReviews:   AE004969_GR
- KEGG:   ngo:NGO0936
- eggNOG:   COG0231
- GeneTree:   EBGT00050000020580
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   NGON242231:NGO0936-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20880; Mature: 20880

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKF
CCCHHHHCCCCEEEECCCCEEEEEHHHHCCCCCCEEEEEEHHHHHCCCCCCEEEECCCCE
DVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGN
EEEEEECCCCEEEEECCEEEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCC
PISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTEIQVMSYIENGDKVEIDTRTG
EEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCC
EFRKRA
CCCCCC
>Mature Secondary Structure
MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKF
CCCHHHHCCCCEEEECCCCEEEEEHHHHCCCCCCEEEEEEHHHHHCCCCCCEEEECCCCE
DVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGN
EEEEEECCCCEEEEECCEEEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCC
PISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTEIQVMSYIENGDKVEIDTRTG
EEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCC
EFRKRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA