Click here to switch to the map view.

The map label for this gene is pip [H]

Identifier: 161869839

GI number: 161869839

Start: 872467

End: 873399

Strand: Direct

Name: pip [H]

Synonym: NMCC_0870

Alternate gene names: 161869839

Gene position: 872467-873399 (Clockwise)

Preceding gene: 161869838

Following gene: 161869842

Centisome position: 40.52

GC content: 53.7

Gene sequence:

>933_bases
ATGTATGAGATAAAACAGCCTTTTCATAGCGGATACTTGCAGGTGTCTGAAATTCATCAAATTTATTGGGAAGAGTCGGG
CAATCCCGACGGTGTGCCGGTCATTTTCCTGCACGGCGGACCGGGCGCGGGGGCTTCGCCTGAATGTCGGGGTTTTTTCA
ATCCCGATGTGTTCCGCATCGTCATCATCGACCAGCGCGGTTGCGGACGTTCGCGCCCGTATGCTTGTGCGGAAGACAAT
ACGACTTGGGATTTGGTGGCGGATATTGAAAAAGTCCGTGAAATGCTGGGTATCAGGAAATGGCTGGTGTTCGGCGGTTC
GTGGGGCAGCACTTTGTCGCTGGCTTATGCCCAAACCCATCCTGAACGGGTAAAGGGATTGGTATTGCGCGGGATATTTT
TGTGCAGGCCGTCTGAAACGGCGTGGCTGAACGAGGCGGGCGGTGTGAGCCGGATTTATCCGGAACAATGGCAAAAATTT
GTCGCGCCGATTGCTGAAAATCGACGGAACCGGCTGATTGAGGCGTATCACGGGTTGCTGTTTCATCAAGATGAAGAAGT
GTGCCTGTCTGCCGCAAAGGCTTGGGCGGATTGGGAAAGCTATCTGATCCGTTTCGAGCCGGAGGAAGTGGATGAAGATG
CTTATGCCTCGCTGGCAATCGCGCGTTTGGAAAACCATTATTTTGTCAACGGCGGCTGGTTGCAGGGCGATAGGGCGATT
TTGAACAATATCGGCAAAATACGGCATATCCCGACCATTATCGTGCAGGGGCGGTATGATTTGTGTACGCCGATGCAGAG
TGCGTGGGCGCTGTCGAAAGCCTTTCCGGAAGCGGAATTGAGGGTGGTTCAGGCAGGGCATCGTGCGTTCGATCCGCCTT
TGGCGGATGCGCTGGTTCAGGCGGTTGAGGATATTTTGCCCCGTTTGTTGTAA

Upstream 100 bases:

>100_bases
CGCGATTTTTCGGAATTTGCCTTTCGGGGCGGCTTGTGTTTTGTGCGGGATGTCGCGTGTCGGGATGTTCGGATTGTCAG
AAGCAATATAGGAGAAGATG

Downstream 100 bases:

>100_bases
AAAGTTCCGCATAAAAAAGCAGCTTCTGTTTGGAAGCTGCTTTTGTTTTGAATGGTTTAACGCAGTTCGGAATGGAGTTT
GCCCAATAATGCGGATGCGT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDN
TTWDLVADIEKVREMLGIRKWLVFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKF
VAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAI
LNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLADALVQAVEDILPRLL

Sequences:

>Translated_310_residues
MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDN
TTWDLVADIEKVREMLGIRKWLVFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKF
VAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAI
LNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLADALVQAVEDILPRLL
>Mature_310_residues
MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDN
TTWDLVADIEKVREMLGIRKWLVFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKF
VAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAI
LNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLADALVQAVEDILPRLL

Specific function: Hydrolyzes peptides having the structure Pro-Y-Z to yield free proline. Also hydrolyzes the dipeptide Pro-Gly [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35019; Mature: 35019

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRI
CCCCCCCHHCCCEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEE
VIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIRKWLVFGGSWGSTLSLAYAQTH
EEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCC
PERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKFVAPIAENRRNRLIEAYHGLL
HHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAI
CCCCHHHHHHHHHHHHCHHHHEEEECHHHCCCHHHHHHHHHHHCCEEEEECCEECCCHHH
LNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLADALVQ
HHCCHHHHCCCEEEEECCCHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
AVEDILPRLL
HHHHHHHHCC
>Mature Secondary Structure
MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRI
CCCCCCCHHCCCEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEE
VIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIRKWLVFGGSWGSTLSLAYAQTH
EEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCC
PERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKFVAPIAENRRNRLIEAYHGLL
HHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAI
CCCCHHHHHHHHHHHHCHHHHEEEECHHHCCCHHHHHHHHHHHCCEEEEECCEECCCHHH
LNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLADALVQ
HHCCHHHHCCCEEEEECCCHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
AVEDILPRLL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934933 [H]