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The map label for this gene is dapL [H]

Identifier: 161869826

GI number: 161869826

Start: 858206

End: 859393

Strand: Direct

Name: dapL [H]

Synonym: NMCC_0855

Alternate gene names: 161869826

Gene position: 858206-859393 (Clockwise)

Preceding gene: 161869825

Following gene: 161869827

Centisome position: 39.85

GC content: 50.17

Gene sequence:

>1188_bases
ATGAATACCTTACTCAACCAACTCAAACCCTATCCCTTTGCCCGACTGCGTGAAGCGATGCAGGGCATTTCCGCGCCTGA
AGGCATGGAAGCCGTCCCCTTGCACATCGGCGAACCGAAACATCCGACACCGAAAGTCATTACGGATGCGCTGACCGCCT
CATTGCACGAGTTGGAAAAATATCCGCTGACTGCGGGTCTGCCTGAACTGCGTCAGGCGTGTGCAAACTGGTTAAAACGC
CGTTATGACGGCTTGACAGTGGATGCAGATAATGAAATTCTGCCGGTTTTAGGCAGTAGGGAGGCGTTGTTTTCTTTTGT
TCAAACCGTGTTGAACCCTGTTTCGGACGGCATCAAACCCGCAATTGTCAGCCCGAATCCCTTTTATCAGATTTACGAAG
GTGCGACACTTTTGGGCGGCGGTGAAATCCATTTTGCCAATTGCCCCGCGCCGTCTTTCAACCCCGATTGGCGCAGTATT
TCCGAAGAGGTTTGGAAACGCACCAAACTGGTGTTCGTCTGCTCGCCCAACAACCCCAGCGGCAGCGTGCTGGATTTGGA
CGGATGGAAAGAAATTTTTGATTTACAGGATAAATATGGTTTCATTATTGCCTCGGATGAATGCTATTCCGAAATCTATT
TCGACGGCAACAAACCTTTAGGCTGCCTGCAGGCCGCTGCACAGTTGGGTCGAAGCAGGCAAAAACTGCTTATGTTCACC
AGTTTGTCCAAGCGGTCCAATGTTCCAGGTTTGCGTTCCGGTTTTGTCGCCGGCGATGCCGAACTGCTTAAAAACTTTCT
GCTTTACAGAACCTATCACGGCAGTGCAATGAGCATTCCCATGCAGCGCGCAAGCATTGCCGCTTGGGATGACGAACAGC
ACGTTATCGACAACCGCCGCCTGTATCAGGAAAAATTTGAGCGCGTTATTCCCATTTTGCAACAGGTATTTGACGTTAAA
TTACCGGATGCCTCGTTTTACATCTGGTTGAAAGTCCCCGATGGCGACGATTTGGCATTTGCACGCAATTTATGGCAAAA
AGCCGCTATCCAAGTATTGCCCGGACGTTTTTTGGCACGGGATACCGAACAGGGCAATCCCGGGGAAGGTTATGTGCGTA
TCGCTTTGGTTGTCGATGTCGCAACTTGTGTCAAAGCTGCGGAAACCATTGTTTCCCTATATCGGTAA

Upstream 100 bases:

>100_bases
CGGCAGTACGGGTTCTCACTAAAAATATAGAATGCCGTCTGAAAGACACGTCAGGTTCAGACGGCATATCTTCCCAATAT
GCCGGTAATCGGAGAACATT

Downstream 100 bases:

>100_bases
AGAATAAAAAATGCCGTCTGAACTTTTGTTCAGACGGCATTTTTCAATATTTTACGGTTGAATTTGCTATAACGGTATTT
ATAGTGGATTAACAAAAATC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNTLLNQLKPYPFARLREAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEKYPLTAGLPELRQACANWLKR
RYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSI
SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEIFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFT
SLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPMQRASIAAWDDEQHVIDNRRLYQEKFERVIPILQQVFDVK
LPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVVDVATCVKAAETIVSLYR

Sequences:

>Translated_395_residues
MNTLLNQLKPYPFARLREAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEKYPLTAGLPELRQACANWLKR
RYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSI
SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEIFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFT
SLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPMQRASIAAWDDEQHVIDNRRLYQEKFERVIPILQQVFDVK
LPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVVDVATCVKAAETIVSLYR
>Mature_395_residues
MNTLLNQLKPYPFARLREAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEKYPLTAGLPELRQACANWLKR
RYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSI
SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEIFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFT
SLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPMQRASIAAWDDEQHVIDNRRLYQEKFERVIPILQQVFDVK
LPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVVDVATCVKAAETIVSLYR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=23.4256926952141, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=23.4256926952141, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI95147551, Length=331, Percent_Identity=24.4712990936556, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI169881279, Length=331, Percent_Identity=24.4712990936556, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788722, Length=405, Percent_Identity=26.4197530864197, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786816, Length=370, Percent_Identity=23.7837837837838, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788627, Length=234, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=21.9512195121951, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=25.065963060686, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=25.065963060686, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28573069, Length=283, Percent_Identity=25.7950530035336, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646114, Length=283, Percent_Identity=25.7950530035336, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573067, Length=283, Percent_Identity=25.7950530035336, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573065, Length=283, Percent_Identity=25.7950530035336, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859735, Length=390, Percent_Identity=24.3589743589744, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44121; Mature: 44121

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLLNQLKPYPFARLREAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEK
CCCHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKP
CCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCC
AIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPS
EEECCCCCEEEECCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCC
GSVLDLDGWKEIFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFT
CCEEECCCHHHHHHHHHHCCEEEECCHHHEHEEECCCCCHHHHHHHHHHCCCHHHHHHHH
SLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPMQRASIAAWDDEQHVIDNRR
HHHHHCCCCCHHCCCCCCCHHHHHHHHHHHEECCCEEECCHHHCEEECCCCCHHHHHHHH
LYQEKFERVIPILQQVFDVKLPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLAR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHCC
DTEQGNPGEGYVRIALVVDVATCVKAAETIVSLYR
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTLLNQLKPYPFARLREAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEK
CCCHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
YPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKP
CCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCC
AIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPS
EEECCCCCEEEECCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCC
GSVLDLDGWKEIFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFT
CCEEECCCHHHHHHHHHHCCEEEECCHHHEHEEECCCCCHHHHHHHHHHCCCHHHHHHHH
SLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPMQRASIAAWDDEQHVIDNRR
HHHHHCCCCCHHCCCCCCCHHHHHHHHHHHEECCCEEECCHHHCEEECCCCCHHHHHHHH
LYQEKFERVIPILQQVFDVKLPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLAR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHCC
DTEQGNPGEGYVRIALVVDVATCVKAAETIVSLYR
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA