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The map label for this gene is pgp [H]

Identifier: 161869553

GI number: 161869553

Start: 592903

End: 593565

Strand: Reverse

Name: pgp [H]

Synonym: NMCC_0568

Alternate gene names: 161869553

Gene position: 593565-592903 (Counterclockwise)

Preceding gene: 161869554

Following gene: 161869551

Centisome position: 27.56

GC content: 61.24

Gene sequence:

>663_bases
ATGATACAAGCCGTATTGTTCGACCTCGATGGCACGCTCGCCGACACCGCCCTAGACCTCGGCGGCGCACTCAATACCCT
GCTCGCCCGCCACGGACTGCCGCCCAAAAGCATGGACGAAATCCGCAACCAAGCCAGCCACGGCGCGGCAGGACTGATCA
AACTCGGCGCAGGCATCACCCCCGACCATCCCGACTATGCCCGATGGCGCACCGAATATCTGGAGGAATACGACCGCCGC
TACGCCCAAGACACCGAGCTCTTTGACGGCGTGAACGAACTCATCGCCGAACTCGACAGACGCGGCATCAAATGGGGCAT
CATCACCAACAAACCCATGCGCTTCACCGACAAACTCGCCCCCAAACTCGGCTTCATCATCCCACCCGCCGTCGTCGTCA
GCGGCGACACCTGCGGCGAACCCAAGCCCAGCATCAAACCCATGCTGTATGCGTGCGGACAAATCCACGCCGACCCGCAA
CACACACTCTACGTCGGCGATGCCGAACGCGACATCCAAGCAGGCCGCAACGCCGGCATGAAAACCGTCCTCGCCGAATG
GGGCTACATCGCTCCCGAAGACGATACCGGCTCATGGCAGGCGGATTTCCACATCCGCACGCCGCTCGATCTGCTCGAAT
GTCTGGACAAAATACAGCCCTGA

Upstream 100 bases:

>100_bases
TCGAATTGGATATGTTGGAAGATTTCGAACAGGGTTTGAAACAAAATAAACATGCCGTCTGAAACCCTTCAGTCCCGCAC
TTTATAAAAAAGGAAAACAC

Downstream 100 bases:

>100_bases
AAAATATCCGCCCCACAAACATATAGTGGATTAAATCTAAACCAGTACGTCGTTGCCTCGCCTTAGCTCAAAGAGAACGA
TTCTCTAAGGTGCTGAAGCA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 2; PGPase2 [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIQAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRNQASHGAAGLIKLGAGITPDHPDYARWRTEYLEEYDRR
YAQDTELFDGVNELIAELDRRGIKWGIITNKPMRFTDKLAPKLGFIIPPAVVVSGDTCGEPKPSIKPMLYACGQIHADPQ
HTLYVGDAERDIQAGRNAGMKTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKIQP

Sequences:

>Translated_220_residues
MIQAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRNQASHGAAGLIKLGAGITPDHPDYARWRTEYLEEYDRR
YAQDTELFDGVNELIAELDRRGIKWGIITNKPMRFTDKLAPKLGFIIPPAVVVSGDTCGEPKPSIKPMLYACGQIHADPQ
HTLYVGDAERDIQAGRNAGMKTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKIQP
>Mature_220_residues
MIQAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRNQASHGAAGLIKLGAGITPDHPDYARWRTEYLEEYDRR
YAQDTELFDGVNELIAELDRRGIKWGIITNKPMRFTDKLAPKLGFIIPPAVVVSGDTCGEPKPSIKPMLYACGQIHADPQ
HTLYVGDAERDIQAGRNAGMKTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKIQP

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=208, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24279; Mature: 24279

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRNQASHGAAGLIKLGAGIT
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHEECCCCC
PDHPDYARWRTEYLEEYDRRYAQDTELFDGVNELIAELDRRGIKWGIITNKPMRFTDKLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
PKLGFIIPPAVVVSGDTCGEPKPSIKPMLYACGQIHADPQHTLYVGDAERDIQAGRNAGM
HHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCCH
KTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKIQP
HHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MIQAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRNQASHGAAGLIKLGAGIT
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHEECCCCC
PDHPDYARWRTEYLEEYDRRYAQDTELFDGVNELIAELDRRGIKWGIITNKPMRFTDKLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
PKLGFIIPPAVVVSGDTCGEPKPSIKPMLYACGQIHADPQHTLYVGDAERDIQAGRNAGM
HHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCCH
KTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKIQP
HHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]