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The map label for this gene is hisE [H]

Identifier: 161869535

GI number: 161869535

Start: 572108

End: 572494

Strand: Reverse

Name: hisE [H]

Synonym: NMCC_0549

Alternate gene names: 161869535

Gene position: 572494-572108 (Counterclockwise)

Preceding gene: 161869536

Following gene: 161869534

Centisome position: 26.59

GC content: 49.61

Gene sequence:

>387_bases
TTGCCCGAGAGCAGCCGTTTAGCCTATCATTCCGAACAAACAGAAACAAACAGAAGGAAAATCATGGGAGATTCCGTACT
ATCCGCCATCCAACAAACCATCACCCAGCGAAAATCTGCCAATCCGTCCGAATCTTACGTCGCACAGCTCTTGCATAAGG
GCGAAGACAAAATCCTAAAAAAAGTGATTGAAGAGGCGGGCGAAGTGTTGATGGCATCCAAAGACAAAAACCCGTCCCAC
CTGGTTTACGAAGTTGCCGACTTATGGTTTCACACCATGATTCTTCTGACACACCACGACCTGAAGGCGGAAGACGTATT
GGACGAACTTGCGCGCCGCCAAGGTTTGTCGGGCTTGGCCGAAAAAGCCGCTCGCACAGAATCTTGA

Upstream 100 bases:

>100_bases
TTATTGTGAGTCCAAACCTGTAAGCAAATTACATTTGCAACAGCACAAATGCCGTCTGAAACGCTCAGACGGCATTTTCC
AACGAAGCGCAACAGGCGTA

Downstream 100 bases:

>100_bases
ATTTATATTAAAATCCGCACTTTCCCACATTCAATCCGTCTGACCGCTTTTCAGACGGCATCGGAGCCGTTATGGACAAC
TGTATTTTCTGCAAAATCGC

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MPESSRLAYHSEQTETNRRKIMGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILKKVIEEAGEVLMASKDKNPSH
LVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLAEKAARTES

Sequences:

>Translated_128_residues
MPESSRLAYHSEQTETNRRKIMGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILKKVIEEAGEVLMASKDKNPSH
LVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLAEKAARTES
>Mature_127_residues
PESSRLAYHSEQTETNRRKIMGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILKKVIEEAGEVLMASKDKNPSHL
VYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLAEKAARTES

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 14412; Mature: 14280

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESSRLAYHSEQTETNRRKIMGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILK
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
KVIEEAGEVLMASKDKNPSHLVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHH
EKAARTES
HHHHCCCC
>Mature Secondary Structure 
PESSRLAYHSEQTETNRRKIMGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILK
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
KVIEEAGEVLMASKDKNPSHLVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHH
EKAARTES
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA