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The map label for this gene is corC [H]

Identifier: 161869465

GI number: 161869465

Start: 495834

End: 496658

Strand: Reverse

Name: corC [H]

Synonym: NMCC_0477

Alternate gene names: 161869465

Gene position: 496658-495834 (Counterclockwise)

Preceding gene: 161869467

Following gene: 161869461

Centisome position: 23.06

GC content: 53.82

Gene sequence:

>825_bases
ATGGACGGCGCACAACCGAAAACGAATTTTTTTGAACGCCTGATTGCCCGACTCGCCCGCGAACCCGATTCCGCCGAAGA
CGTATTAAACCTGCTTCGGCAGGCGCACGAGCAGGAAGTATTTGATGCGGATACGCTTTTAAGGTTGGAAAAAGTCCTCG
ATTTTTCCGATTTGGAAGTGCGCGACGCGATGATTACGCGCAGCCGTATGAACGTTTTAAAAGAAAACGACAGCATCGAG
CGCATCACCGCCTACGTTATCGATACCGCCCATTCGCGCTTCCCCGTCATCGGCGAAGACAAAGACGAAGTTTTGGGCAT
TTTGCACGCCAAAGACCTGCTCAAATATATGTTTAACCCCGAGCAGTTCCACCTCAAATCCATTCTCCGCCCCGCCGTCT
TCGTCCCCGAAGGCAAATCGCTGACCGCCCTTTTAAAAGAGTTCCGCGAACAGCGCAACCATATGGCGATTGTCATCGAC
GAATACGGCGGCACATCCGGCTTGGTCACCTTTGAAGACATCATCGAGCAAATCGTCGGCGAAATCGAAGACGAGTTTGA
CGAAGACGATAGCGCCGACAATATCCATGCCGTTTCTTCCGAACGCTGGCGCATCCATGCAGCTACCGAAATCGAAGACA
TCAACACCTTCTTCGGCACGGAATACAGCAGCGAAGAAGCCGACACCATTGGCGGCCTGGTCATTCAAGAGTTGGGACAT
CTGCCCGTGCGCGGCGAAAAAGTCCTTATCGGCGGTTTGCAGTTCACCGTCGCACGCGCCGACAACCGCCGCCTGCATAC
GCTGATGGCGACCCGCGTGAAGTAA

Upstream 100 bases:

>100_bases
CACATCGAAGACGATGAAGCCGAAATAATGGAAGCCGAAGAAATCCGCCTGATGCGGGCGGCAGGCTTCCCCAACCCCTA
CCAAGAGGACGGACATTAAA

Downstream 100 bases:

>100_bases
GCACCGCCGTTTCTGCACAGTTTAGGATGACGGTACGGGCGTTTTCTGTTTCAATCCGCCCCATCCGCCAAACATAAAAA
TGCCGTCTGAAGCCGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDGAQPKTNFFERLIARLAREPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAMITRSRMNVLKENDSIE
RITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMFNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVID
EYGGTSGLVTFEDIIEQIVGEIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELGH
LPVRGEKVLIGGLQFTVARADNRRLHTLMATRVK

Sequences:

>Translated_274_residues
MDGAQPKTNFFERLIARLAREPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAMITRSRMNVLKENDSIE
RITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMFNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVID
EYGGTSGLVTFEDIIEQIVGEIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELGH
LPVRGEKVLIGGLQFTVARADNRRLHTLMATRVK
>Mature_274_residues
MDGAQPKTNFFERLIARLAREPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAMITRSRMNVLKENDSIE
RITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMFNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVID
EYGGTSGLVTFEDIIEQIVGEIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELGH
LPVRGEKVLIGGLQFTVARADNRRLHTLMATRVK

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=231, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1786879, Length=266, Percent_Identity=49.6240601503759, Blast_Score=234, Evalue=3e-63,
Organism=Escherichia coli, GI87082033, Length=231, Percent_Identity=27.7056277056277, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693175, Length=206, Percent_Identity=28.6407766990291, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788119, Length=248, Percent_Identity=27.0161290322581, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=25.764192139738, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31151; Mature: 31151

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGAQPKTNFFERLIARLAREPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMFNP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
EQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVIDEYGGTSGLVTFEDIIEQIVG
HHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHH
EIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELGH
HHHHHCCCCCCCCCEEECCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LPVRGEKVLIGGLQFTVARADNRRLHTLMATRVK
CCCCCCEEEEECEEEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MDGAQPKTNFFERLIARLAREPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMFNP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
EQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVIDEYGGTSGLVTFEDIIEQIVG
HHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEHHHHHHHHHH
EIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELGH
HHHHHCCCCCCCCCEEECCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LPVRGEKVLIGGLQFTVARADNRRLHTLMATRVK
CCCCCCEEEEECEEEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]