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The map label for this gene is recG [H]

Identifier: 161869430

GI number: 161869430

Start: 455284

End: 457326

Strand: Direct

Name: recG [H]

Synonym: NMCC_0438

Alternate gene names: 161869430

Gene position: 455284-457326 (Clockwise)

Preceding gene: 161869429

Following gene: 161869433

Centisome position: 21.14

GC content: 58.3

Gene sequence:

>2043_bases
ATGATGTCGCCCGAAACCCGAAAACAGCTCAAAATCACCGATGTTTCCGCCAAGAAGCTCGACAAACTCAACCTCCATAC
CGCGTGGGATTTGGTGTTGCACCTGCCGCTGCGTTACGAGGACGAGACGCACATTATGCCGATTAAGGACGCGCCGATTG
GCGTGCCGTGTCAGGTCGAGGGGGAGGTTATCCATCAGGAAGTAACGTTCAAACCGCGCAAGCAGCTGATTGTCCAAATC
GCCGACGGCTCCGGCAGCGTCCTTTTTCTGCGCTTCATCCACTTTTACGCCAGCCATCAGAAACAGACGGCGGTCGGCAA
ACGCATCCGCGCCGTGGGCGAAATCAAACACGGCTTTTACGGCGACGAGATGATTCATCCCAAAATCCGCGATGCCGAGG
GCGGCGGTTTGGCGGAAAGCCTCACGCCGGTTTACCCGACCGTAAACGGTTTGAACCAGCCCACTTTGCGCCGTATTATT
CAGACGGCGTTGGACGTTACGCCGCTGCACGACACGCTGCCCGATGCCCTGCTGTGCCGTCTGAAGCTGCCACACCTCGC
CGAAAGCCTGCGTCTTTTGCATTCGCCGCCGCCGAGTTTCACGATTCATCAGCTTTCAGACGGCACGCTGCCTGCATGGC
AACGGCTCAAATTCGACGAACTTTTGGCGCAACAGCTTTCGATGCGCTTGGCGCGACAGAAGCGTATCGGCGGCACGGCG
GCGGCATTGGGCGGCGACGGCACATTGACCCAAGCCCTGCGCCAAGCCCTGCCGTTTGCCCTGACCGATGCGCAAGAAAA
AGTTGTTTCCGAAATCTGCCGCGATATGGCGCAAACCTACCCGATGCACCGCCTGCTGCAGGGCGATGTCGGCAGCGGCA
AAACCATTGTGGCTGCTTTGTCTGCTTTGACGGCTATCGAATCCGGTGCGCAGGTGGCTGTAATGGCGCCCACTGAAATC
CTTGCCGAACAGCATTTTATTAAATTTAAACAATGGCTCGAACCTTTGGGCATTGAAGTTGTCCGCCTTTTTGGCAGTTT
GCGTAAAAAAGCCAAAGACGAAGCCAAAGCCAAACTGGCTGACGGCAGCGTCAAAATCGCCGTCGGCACGCACGCCCTGT
TTTCAGACGGCGTGGCGTTTCACAATTTGGGCTTGACCATTGTGGACGAACAGCACCGTTTCGGCGTTGCCCAACGCCTC
GCCCTCAAAAACAAAGGGCGCGAAGTCCATCAGCTGATGATGTCCGCCACGCCCATCCCGCGCACGCTTGCGATGAGTTT
TTTCGCCGATTTGGACGTGTCCGTCATCGACGAATTGCCGCCCGGGCGCACACCGATTAAAACGCGCCTCGTCAACAACG
TCCGCCGTGCCGAAGTCGAAGGCTTCGTCCTCGGCACTTGCCGAAAAGGGCGGCAGGCGTATTGGGTCTGCCCATTGATT
GAAGAAAGCGAAACCCTGCAACTGCAAACCGCCGCCGAAACCCTCGCCCGGCTTCAGACGGCATTGCCCGAACTCAATAT
CGGACTGGTACACGGGCGCATGAAGGCCGCCGAAAAGGCCGAAGTGATGGCGCGGTTTTCTTCGGGGGGGCTGAACGTCT
TGGTCGCCACCACCGTCATCGAAGTCGGCGTAGATGTGCCCAATGCCGCCCTGATGGTCATCGAACACGCCGAGCGCATG
GGCTTGGCGCAGCTGCACCAATTACGCGGTCGGGTCGGGCGCGGCGCGGCAGAAAGCGTGTGCGTCCTCCTGTTTGCCGA
ACCCTTGGGCGAACTCGCCAAAGCGCGGTTGAAAGTGATTTACGAACACACCGACGGCTTTGAAATCGCCCGCCAAGACC
TCAATATCCGCGGCCCCGGCGAATTTCTCGGCGCGCGCCAAAGCGGCGTGCCTATGCTGCGCTTCGCCAAGCTTGAAGAA
GACTTACACCTTTTGGAACAAGTGCGCGAAATCGCCCCGATGCTGATTGAGCAAAACCCCGAAATCGTCGAAGCGCATTT
GGCAAGGTGGCTTTCCGGCAGGGAAGGGTATTTGGGCGTGTGA

Upstream 100 bases:

>100_bases
GCCGCCGGGGCTTGATTCCTGCCTGTCGATGCCGTCTGAATCCGTTTCAGACGGCATTTTTGTTTTCGGATAAAATAGGC
GCGTCCAAAGGAATCTGCCT

Downstream 100 bases:

>100_bases
GCAAAATGCCGTCTGAAATATTGGAAAAAAGTGTAACGGAAATCTGATTTTGCATTATTTTTGACACATTTTCATGATTT
TAAATCACGTCATTCCCAAG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MMSPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPIGVPCQVEGEVIHQEVTFKPRKQLIVQI
ADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFYGDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRII
QTALDVTPLHDTLPDALLCRLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGTA
AALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAALSALTAIESGAQVAVMAPTEI
LAEQHFIKFKQWLEPLGIEVVRLFGSLRKKAKDEAKAKLADGSVKIAVGTHALFSDGVAFHNLGLTIVDEQHRFGVAQRL
ALKNKGREVHQLMMSATPIPRTLAMSFFADLDVSVIDELPPGRTPIKTRLVNNVRRAEVEGFVLGTCRKGRQAYWVCPLI
EESETLQLQTAAETLARLQTALPELNIGLVHGRMKAAEKAEVMARFSSGGLNVLVATTVIEVGVDVPNAALMVIEHAERM
GLAQLHQLRGRVGRGAAESVCVLLFAEPLGELAKARLKVIYEHTDGFEIARQDLNIRGPGEFLGARQSGVPMLRFAKLEE
DLHLLEQVREIAPMLIEQNPEIVEAHLARWLSGREGYLGV

Sequences:

>Translated_680_residues
MMSPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPIGVPCQVEGEVIHQEVTFKPRKQLIVQI
ADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFYGDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRII
QTALDVTPLHDTLPDALLCRLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGTA
AALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAALSALTAIESGAQVAVMAPTEI
LAEQHFIKFKQWLEPLGIEVVRLFGSLRKKAKDEAKAKLADGSVKIAVGTHALFSDGVAFHNLGLTIVDEQHRFGVAQRL
ALKNKGREVHQLMMSATPIPRTLAMSFFADLDVSVIDELPPGRTPIKTRLVNNVRRAEVEGFVLGTCRKGRQAYWVCPLI
EESETLQLQTAAETLARLQTALPELNIGLVHGRMKAAEKAEVMARFSSGGLNVLVATTVIEVGVDVPNAALMVIEHAERM
GLAQLHQLRGRVGRGAAESVCVLLFAEPLGELAKARLKVIYEHTDGFEIARQDLNIRGPGEFLGARQSGVPMLRFAKLEE
DLHLLEQVREIAPMLIEQNPEIVEAHLARWLSGREGYLGV
>Mature_680_residues
MMSPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPIGVPCQVEGEVIHQEVTFKPRKQLIVQI
ADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFYGDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRII
QTALDVTPLHDTLPDALLCRLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGTA
AALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAALSALTAIESGAQVAVMAPTEI
LAEQHFIKFKQWLEPLGIEVVRLFGSLRKKAKDEAKAKLADGSVKIAVGTHALFSDGVAFHNLGLTIVDEQHRFGVAQRL
ALKNKGREVHQLMMSATPIPRTLAMSFFADLDVSVIDELPPGRTPIKTRLVNNVRRAEVEGFVLGTCRKGRQAYWVCPLI
EESETLQLQTAAETLARLQTALPELNIGLVHGRMKAAEKAEVMARFSSGGLNVLVATTVIEVGVDVPNAALMVIEHAERM
GLAQLHQLRGRVGRGAAESVCVLLFAEPLGELAKARLKVIYEHTDGFEIARQDLNIRGPGEFLGARQSGVPMLRFAKLEE
DLHLLEQVREIAPMLIEQNPEIVEAHLARWLSGREGYLGV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=672, Percent_Identity=52.6785714285714, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=405, Percent_Identity=39.5061728395062, Blast_Score=251, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74901; Mature: 74901

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPIGVPCQVE
CCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHEECCCEECCCCCEEEECCCCCCCCCEEC
GEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFY
CHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
GDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRIIQTALDVTPLHDTLPDALLCR
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGTA
HCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
AALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAAL
EECCCCHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHH
SALTAIESGAQVAVMAPTEILAEQHFIKFKQWLEPLGIEVVRLFGSLRKKAKDEAKAKLA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
DGSVKIAVGTHALFSDGVAFHNLGLTIVDEQHRFGVAQRLALKNKGREVHQLMMSATPIP
CCCEEEEEECHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
RTLAMSFFADLDVSVIDELPPGRTPIKTRLVNNVRRAEVEGFVLGTCRKGRQAYWVCPLI
HHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEEE
EESETLQLQTAAETLARLQTALPELNIGLVHGRMKAAEKAEVMARFSSGGLNVLVATTVI
CCCCCEEHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEHHHHHH
EVGVDVPNAALMVIEHAERMGLAQLHQLRGRVGRGAAESVCVLLFAEPLGELAKARLKVI
HHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YEHTDGFEIARQDLNIRGPGEFLGARQSGVPMLRFAKLEEDLHLLEQVREIAPMLIEQNP
EECCCCHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EIVEAHLARWLSGREGYLGV
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMSPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPIGVPCQVE
CCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHEECCCEECCCCCEEEECCCCCCCCCEEC
GEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFY
CHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
GDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRIIQTALDVTPLHDTLPDALLCR
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGTA
HCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
AALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAAL
EECCCCHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHH
SALTAIESGAQVAVMAPTEILAEQHFIKFKQWLEPLGIEVVRLFGSLRKKAKDEAKAKLA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
DGSVKIAVGTHALFSDGVAFHNLGLTIVDEQHRFGVAQRLALKNKGREVHQLMMSATPIP
CCCEEEEEECHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
RTLAMSFFADLDVSVIDELPPGRTPIKTRLVNNVRRAEVEGFVLGTCRKGRQAYWVCPLI
HHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEEE
EESETLQLQTAAETLARLQTALPELNIGLVHGRMKAAEKAEVMARFSSGGLNVLVATTVI
CCCCCEEHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEHHHHHH
EVGVDVPNAALMVIEHAERMGLAQLHQLRGRVGRGAAESVCVLLFAEPLGELAKARLKVI
HHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YEHTDGFEIARQDLNIRGPGEFLGARQSGVPMLRFAKLEEDLHLLEQVREIAPMLIEQNP
EECCCCHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EIVEAHLARWLSGREGYLGV
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]