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The map label for this gene is ribD [H]

Identifier: 161869403

GI number: 161869403

Start: 423034

End: 423951

Strand: Reverse

Name: ribD [H]

Synonym: NMCC_0411

Alternate gene names: 161869403

Gene position: 423951-423034 (Counterclockwise)

Preceding gene: 161869404

Following gene: 161869402

Centisome position: 19.69

GC content: 59.8

Gene sequence:

>918_bases
ATGGCACAAGGCGCGACCGCCTTTGTTACCCTCGAACCGTGCAGCCATTACGGGCGTACCCCGCCCTGCGCCGAAGCTCT
GCTCCGTTCCGGCGTAACACGCGTCGTTGCCGCCATGCGCGACCCCAACCCGCTGGTTGCCGGCAAAGGGCTTGCCATGC
TCGAAGCAGCAGGCATCAAGACGGAATGCGGTTTACTCGAACATCAGGCAAGGGAACTCAACCGAGGCTTCCTGTCGCGC
ATCGAACGCCGCCGCCCCTTCGTCCGCCTCAAATGCGCCGTTTCGCTGGACGGCAAAACCGCCCTTTCAGACGGCAGCAG
CTTTTGGATTACCGGCGAAGACGCGCGTGCCGACGTACAGGTTTTGCGTGCCGAAAGCTGCGCGGTGCTGACCGGCATCG
GCACGGTGTTGGCGGACAATCCCCGGCTCAACGTCCGCGCTTTTCCAACTTTGCGCCAACCCGCACGCATCGTTTTAGAC
AGCCGCCTGCGCCTGCCCTTGGACAGCCACCTTCTGACCGACGGACAATCTCCAACCTACATCGCCACCTTGGAACGCGA
TGAAGATAAACTCCGCCCCTATCGGGAACACGCACACATCCGCATCCTGATGCCGTCTGAAACGGCAGACGGCAAAATCG
ACCTGCACCACCTGATGCGCCTCCTTGCCGACGAAGGTTTCGGCGAAATCATGGTCGAAGCAGGCTCCGAACTCACATCC
GCATTTTTGGCAGAAGATTTGGCGGACGAAATCGTTTTATACCGCTCGCCCAAAATCCTCGGCGGCGGCAGCGGTTTATT
TTGCCTGCCCGAAAACCGCGCCGCCCTTTCCGCACCGCCCTTGTGGACACCTGTTTCAAGCGAAATCCTCGGACACGACA
TCAAAACCGTGTTCCGAAAAAACGGCAACGCCTTTTAA

Upstream 100 bases:

>100_bases
CTGCGTTATCGCACACGGCAGCCAAATTGTCGGGCAAGGCTTCCACGTCAAAGCGGGCGAACCCCATGCCGAAGTCCACG
CCCTGCGTCAGGCGGGCGAA

Downstream 100 bases:

>100_bases
AGGGTTTGCGCCATTTCACTATATAATAACGCCGATAAAAAACGGCACCATTCAGACCGCCGCCCACCCGAAAAAGCGCA
ACCCGGACTGCCGCACTCCG

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase/phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLAMLEAAGIKTECGLLEHQARELNRGFLSR
IERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLD
SRLRLPLDSHLLTDGQSPTYIATLERDEDKLRPYREHAHIRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTS
AFLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRKNGNAF

Sequences:

>Translated_305_residues
MAQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLAMLEAAGIKTECGLLEHQARELNRGFLSR
IERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLD
SRLRLPLDSHLLTDGQSPTYIATLERDEDKLRPYREHAHIRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTS
AFLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRKNGNAF
>Mature_304_residues
AQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLAMLEAAGIKTECGLLEHQARELNRGFLSRI
ERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLDS
RLRLPLDSHLLTDGQSPTYIATLERDEDKLRPYREHAHIRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTSA
FLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRKNGNAF

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=291, Percent_Identity=45.7044673539519, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 33242; Mature: 33110

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLAMLEAAGIK
CCCCCEEEEEECCHHHCCCCCHHHHHHHHHCHHHHHHHHCCCCCEEECCCEEEEEECCCC
TECGLLEHQARELNRGFLSRIERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQ
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEECCCCEEEEECCCCCCHHH
VLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLDSRLRLPLDSHLLTDGQSPTY
HHHHCCCEEEECCHHHHCCCCCCEEEECCCCCCCHHHEECCCCCCCCCHHEECCCCCCCE
IATLERDEDKLRPYREHAHIRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTS
EEEEECCHHHCCHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCEEECCCHHHHH
AFLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRK
HHHHHHHHHHEEEEECCCEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
NGNAF
CCCCC
>Mature Secondary Structure 
AQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLAMLEAAGIK
CCCCEEEEEECCHHHCCCCCHHHHHHHHHCHHHHHHHHCCCCCEEECCCEEEEEECCCC
TECGLLEHQARELNRGFLSRIERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQ
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEECCCCEEEEECCCCCCHHH
VLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLDSRLRLPLDSHLLTDGQSPTY
HHHHCCCEEEECCHHHHCCCCCCEEEECCCCCCCHHHEECCCCCCCCCHHEECCCCCCCE
IATLERDEDKLRPYREHAHIRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTS
EEEEECCHHHCCHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCCEEECCCHHHHH
AFLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRK
HHHHHHHHHHEEEEECCCEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
NGNAF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]