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The map label for this gene is nrdR [H]

Identifier: 161869404

GI number: 161869404

Start: 424175

End: 424717

Strand: Reverse

Name: nrdR [H]

Synonym: NMCC_0412

Alternate gene names: 161869404

Gene position: 424717-424175 (Counterclockwise)

Preceding gene: 161869405

Following gene: 161869403

Centisome position: 19.72

GC content: 62.06

Gene sequence:

>543_bases
GTGCCGAAGAAGGTCTGGAAATCGCCCGCGCCGCCGGCGTATCGGTTTGACGTTCAGACGGCATCAGGAAGAAACGCTAT
GAAATGCCCGTTTTGCGCCCACCCCGACACCCGCGTCGCCGATTCGCGTCTGATGGAAGAACGCAACGCCGTGCGCCGCC
GCCGCCACTGCCCCAACTGCGGCAAACGCTTCGGCACGCTCGAAACCGCCGAACTCAAAATGCCCGCCGTCATCGGTCCG
GACAAAAAACGCTCGCCCTTTAATGCACAACGCCTCCGCAACGACCTGACCGCCGCCGCCCGAAAATCCGCCCTGACACC
CGAACAGATCGACGAAACCGTCCGCCTGACGGAACACAGGCTCTACACTTCGGGTCAGCGCGACATCCCCTCTGCCGCAC
TTGCCGACATGGTGCTAAAAGAACTGCTCCGACAAGATACGGAAGCCGCCGTCCGTTTCGCCGCCCTGCACAAACGCTTC
GACAATCCGGCAGACTTTGCCTCGTGGCTGGCGCAAGCCGTCAAAACAGGCGGCAAAGCCTGA

Upstream 100 bases:

>100_bases
CGCGATGAAACGTGGGCGCAACTTGCCGTGAACGAACTGGTCATGTTCCGCGAAGGCAACATCGTCCGACACGACCGTCC
CGAAAACCCCGTCTATATGA

Downstream 100 bases:

>100_bases
TTCCCCCAACCCATACTGATACGGTATCCCTATGTTTTCGGACACAGATATATCCATGATGGAAAACGCCCTCCGACTTG
CCGCTTTGGGGCGTTTTTCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPKKVWKSPAPPAYRFDVQTASGRNAMKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNCGKRFGTLETAELKMPAVIGP
DKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRF
DNPADFASWLAQAVKTGGKA

Sequences:

>Translated_180_residues
MPKKVWKSPAPPAYRFDVQTASGRNAMKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNCGKRFGTLETAELKMPAVIGP
DKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRF
DNPADFASWLAQAVKTGGKA
>Mature_179_residues
PKKVWKSPAPPAYRFDVQTASGRNAMKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNCGKRFGTLETAELKMPAVIGPD
KKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRFD
NPADFASWLAQAVKTGGKA

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=146, Percent_Identity=36.3013698630137, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 20170; Mature: 20039

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKVWKSPAPPAYRFDVQTASGRNAMKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNC
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
GKRFGTLETAELKMPAVIGPDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHR
HHHHCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRFDNPADFASWLAQAVKTGGKA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKKVWKSPAPPAYRFDVQTASGRNAMKCPFCAHPDTRVADSRLMEERNAVRRRRHCPNC
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
GKRFGTLETAELKMPAVIGPDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHR
HHHHCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRFDNPADFASWLAQAVKTGGKA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]