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The map label for this gene is gmhB [H]

Identifier: 161869170

GI number: 161869170

Start: 167443

End: 168006

Strand: Reverse

Name: gmhB [H]

Synonym: NMCC_0166

Alternate gene names: 161869170

Gene position: 168006-167443 (Counterclockwise)

Preceding gene: 161869171

Following gene: 161869169

Centisome position: 7.8

GC content: 56.56

Gene sequence:

>564_bases
ATGAAACTCATCATTCTCGACCGCGACGGCGTCATCAATCAGGACCGCGATGACTTCGTCAAATCCGTTGACGAGTGGAT
ACCTGTCGAAGGCAGCATGGATGCGGTGGCATTTCTGACGCAGGCAGGCTACACCGTCGCCGTTGCCACCAACCAATCCG
GCATCGGGCGCAAATATTTTACCGTTCAAAACCTCACCGAAATGCATGCCAAAATGCACCGCCTCGTCCGTCAGGCAGGC
GGCGAAATCAACGGCATCTGGTTCTGCCCTCATACCGGCGCCGACGGCTGCGGCTGCCGCAAGCCCAAACCGGGTATGAT
TGAAGACATCCTCGAACGCTTCAACGCCCAAGCTTCGGAAACTTGGCTGGTCGGCGACAGCCTGCGCGATTTGCAGGCAA
TCGATGCCGTCGGCGGCAAACCCGCGCTGGTTCTGACCGGAAAAGGCAAAAAAACGCTCTCCCAACACGGACACGAATTG
CCCGAACACACACAGGTTTTCGATACCTTGCTCGATTTCTCACAATACATCATGCAGGAAAACGCCGCACCGCAAGCCGA
CTGA

Upstream 100 bases:

>100_bases
ATAAAATATTGGAGTTAGAGAAACATCTTGTAGCAGAATTTAATCTAGATTTATGTCCTATAATCCCATCCCCGACACGC
CCCAACCCAAAGGAAACGCG

Downstream 100 bases:

>100_bases
ACATACCGCATTTCCGACAAGGCAAAACCATGCTCATCATCCGCAACCTGATTTACTGGCTGATACTCTGTTCCACCCTG
ATTTTCCTCTTTCCCTTTAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYFTVQNLTEMHAKMHRLVRQAG
GEINGIWFCPHTGADGCGCRKPKPGMIEDILERFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHEL
PEHTQVFDTLLDFSQYIMQENAAPQAD

Sequences:

>Translated_187_residues
MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYFTVQNLTEMHAKMHRLVRQAG
GEINGIWFCPHTGADGCGCRKPKPGMIEDILERFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHEL
PEHTQVFDTLLDFSQYIMQENAAPQAD
>Mature_187_residues
MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYFTVQNLTEMHAKMHRLVRQAG
GEINGIWFCPHTGADGCGCRKPKPGMIEDILERFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHEL
PEHTQVFDTLLDFSQYIMQENAAPQAD

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=190, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=30.2158273381295, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20584; Mature: 20584

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYF
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEH
TVQNLTEMHAKMHRLVRQAGGEINGIWFCPHTGADGCGCRKPKPGMIEDILERFNAQASE
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
TWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHELPEHTQVFDTLLDFSQYIMQE
EEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
NAAPQAD
CCCCCCC
>Mature Secondary Structure
MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYF
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEH
TVQNLTEMHAKMHRLVRQAGGEINGIWFCPHTGADGCGCRKPKPGMIEDILERFNAQASE
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
TWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHELPEHTQVFDTLLDFSQYIMQE
EEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
NAAPQAD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]