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The map label for this gene is pilE1 [H]

Identifier: 161869043

GI number: 161869043

Start: 20573

End: 20908

Strand: Reverse

Name: pilE1 [H]

Synonym: NMCC_0026

Alternate gene names: 161869043

Gene position: 20908-20573 (Counterclockwise)

Preceding gene: 161869044

Following gene: 161869042

Centisome position: 0.97

GC content: 52.08

Gene sequence:

>336_bases
GTGGGAATGACGGGATTTAATGATACCGCCGACATAGCATCCACCCCCTCCGACATCAAAGGCAAATATGTTGAGAAAGT
TGAAGTCAAAAACGGCGTCGTTACCGCCACAATGCTTTCAAGCGGCGTAAACAAAGAAATCCAAGGCAAAAAACTCTCCC
TGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCGACGCCAACAACGCCAGCGCC
GACGCCGTTAACAAAGTCACCGGCAACGGCAACGACAAAATCGACACCAAGCACCTGCCGTCAACAGCACCGACAAGAAA
ATCGACACCAAACTAG

Upstream 100 bases:

>100_bases
ACTTCGTCATTCCCGCGCAGGCGGGAATCTAGGTTTGTCGGCGCAGAAACTTATCGGGTAAAAAGGTTTCTCCAGTCCTG
AATCCTAGATTCCCACTTTC

Downstream 100 bases:

>100_bases
AGAAACCTTTTTACCCGATAAGTTTCCGCACCGACGAGGCTGGATTCCCGCCTGCGCGGGAATGACGGCGGAGCGGTTTC
TGTTGCTCCCGATAAATTCC

Product: pilS cassette

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MGMTGFNDTADIASTPSDIKGKYVEKVEVKNGVVTATMLSSGVNKEIQGKKLSLWAKRQDGSVKWFCGQPVTRDANNASA
DAVNKVTGNGNDKIDTKHLPSTAPTRKSTPN

Sequences:

>Translated_111_residues
MGMTGFNDTADIASTPSDIKGKYVEKVEVKNGVVTATMLSSGVNKEIQGKKLSLWAKRQDGSVKWFCGQPVTRDANNASA
DAVNKVTGNGNDKIDTKHLPSTAPTRKSTPN
>Mature_110_residues
GMTGFNDTADIASTPSDIKGKYVEKVEVKNGVVTATMLSSGVNKEIQGKKLSLWAKRQDGSVKWFCGQPVTRDANNASAD
AVNKVTGNGNDKIDTKHLPSTAPTRKSTPN

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 11824; Mature: 11693

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMTGFNDTADIASTPSDIKGKYVEKVEVKNGVVTATMLSSGVNKEIQGKKLSLWAKRQD
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEECCC
GSVKWFCGQPVTRDANNASADAVNKVTGNGNDKIDTKHLPSTAPTRKSTPN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GMTGFNDTADIASTPSDIKGKYVEKVEVKNGVVTATMLSSGVNKEIQGKKLSLWAKRQD
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEECCC
GSVKWFCGQPVTRDANNASADAVNKVTGNGNDKIDTKHLPSTAPTRKSTPN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]