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The map label for this gene is pilE [H]

Identifier: 161869044

GI number: 161869044

Start: 20948

End: 21310

Strand: Reverse

Name: pilE [H]

Synonym: NMCC_0027

Alternate gene names: 161869044

Gene position: 21310-20948 (Counterclockwise)

Preceding gene: 161869045

Following gene: 161869043

Centisome position: 0.99

GC content: 52.89

Gene sequence:

>363_bases
ATGGCTTCAAGCGGCGTAAACAACGAAATCAAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAA
ATGGTTCTGCGGACAGCCGGTTACGCGCAAAGCCCCCACCGGCGCCAACAACGACGAAGTCACCAAGACCGCCGACAACG
AAATCAACACCAAGCACCTGCCGTCAACCTGCCGCGACGCATCATCTGCCAGCCGTACAAAAACACCCGGTTTCGCTTTC
AAATACTTCCAAAAAATCAGCCGTTACCGAGTATTGCCCGAATCACGGCAAATGACCAAAAAACTTCGTCATTCCCGCGC
AGGCGGGAATCTAGGTTTGTCGGCGCAGAAACTTATCGGGTAA

Upstream 100 bases:

>100_bases
GGTGCCGGCGGCGTGATTCCCCCGCACGCCACTTTGATATTTGAAGTCGAGCTGCTGAAAGTGTACGAATAAAGCTGCCC
GGGCAATACCGTCTGACATA

Downstream 100 bases:

>100_bases
AAAGGTTTCTCCAGTCCTGAATCCTAGATTCCCACTTTCGTGGGAATGACGGGATTTAATGATACCGCCGACATAGCATC
CACCCCCTCCGACATCAAAG

Product: pilS cassette

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MASSGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVTRKAPTGANNDEVTKTADNEINTKHLPSTCRDASSASRTKTPGFAF
KYFQKISRYRVLPESRQMTKKLRHSRAGGNLGLSAQKLIG

Sequences:

>Translated_120_residues
MASSGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVTRKAPTGANNDEVTKTADNEINTKHLPSTCRDASSASRTKTPGFAF
KYFQKISRYRVLPESRQMTKKLRHSRAGGNLGLSAQKLIG
>Mature_119_residues
ASSGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVTRKAPTGANNDEVTKTADNEINTKHLPSTCRDASSASRTKTPGFAFK
YFQKISRYRVLPESRQMTKKLRHSRAGGNLGLSAQKLIG

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 13240; Mature: 13109

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVTRKAPTGANNDEVTKTADNEINTKHL
CCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCC
PSTCRDASSASRTKTPGFAFKYFQKISRYRVLPESRQMTKKLRHSRAGGNLGLSAQKLIG
CHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure 
ASSGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVTRKAPTGANNDEVTKTADNEINTKHL
CCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCC
PSTCRDASSASRTKTPGFAFKYFQKISRYRVLPESRQMTKKLRHSRAGGNLGLSAQKLIG
CHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3141743; 10710307; 8645220; 8993351; 9515697 [H]