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The map label for this gene is htpX [H]

Identifier: 161526290

GI number: 161526290

Start: 3408919

End: 3409776

Strand: Reverse

Name: htpX [H]

Synonym: Bmul_3121

Alternate gene names: 161526290

Gene position: 3409776-3408919 (Counterclockwise)

Preceding gene: 161526291

Following gene: 161526289

Centisome position: 98.88

GC content: 66.2

Gene sequence:

>858_bases
ATGTTCAATTGGGTCAAAACGGCGATGCTGATGGCCGCGATCACGGCCCTGTTCATCGTGATCGGCGGCATGATCGGCGG
CTCGCGCGGCATGACGATCGCCCTGCTGTTCGCGCTCGGCATGAATTTCTTCTCGTACTGGTTCTCCGACAAGATGGTGC
TGCGCATGTACAACGCGCAGGAGGTCGACGAGAACACGGCGCCGCAGTTCTACCGGATGGTCCGCGAGCTGGCCACGCGC
GCGAACCTGCCGATGCCGCGTGTCTATCTGATCAACGAGGACGCACCGAACGCGTTTGCGACGGGCCGCAACCCCGAGCA
TGCGGCCGTGGCGGCGACCACCGGCATCCTGCGCGTGCTGTCCGAGCGCGAGATGCGCGGCGTGATGGCGCACGAGCTTG
CGCACGTGAAGCACCGCGACATCCTGATCTCGACGATCACCGCGACGATGGCCGGTGCGATCTCGGCGATCGCGAACTTC
GCGATGTTCTTCGGCGGGCGCGATGAAAACGGCCGGCCGGTCAATCCGATCGCAGGCATCGCGGTCGCATTGCTCGCGCC
GATCGCGGGCGCGCTGATCCAGATGGCGATCTCGCGTGCGCGCGAGTTCGAGGCCGACCGCGGCGGCGCGCAGATCTCCG
GCGATCCGCAAGCGCTCGCGAGCGCGCTCGACAAGATTCATCGCTATGCGGCGGGCATCCCGTTCCAAGCGGCCGAAGCG
CATCCGGCCACCGCGCAGATGATGATCATGAACCCGCTTCACGGCGGCGGTCTGCAGAATCTGTTCTCCACGCACCCGGC
CACCGAGGAGCGCATCGCGCGGCTGATGGAAATGGCGCGCACCGGCCGCTTCGACTGA

Upstream 100 bases:

>100_bases
AAATTTGAATTTTTCCGGCGAGCCCTTATCTAACAGATCGCTTACAATTTCCCGCCGCACAGTCGTGACGGCGGGTTTCC
CCGACGGATAAGGAGTGGGT

Downstream 100 bases:

>100_bases
CGGCGCCCGTCCGCGGCGCCTGTTCCGCGGTCCTTCCCCGATCACCCCGCATGCGTCGCGCTGCGGGGTGATTCATTTGC
GCGTCGTCCGGGCCCCATCC

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPVNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYAAGIPFQAAEA
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD

Sequences:

>Translated_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPVNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYAAGIPFQAAEA
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
>Mature_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATR
ANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANF
AMFFGGRDENGRPVNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYAAGIPFQAAEA
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=272, Percent_Identity=33.4558823529412, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30951; Mature: 30951

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDENTAPQFYRMVRELATRANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANFAMFFGGRDENGRPVNPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYAAGIPFQAAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
CCCHHHEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDENTAPQFYRMVRELATRANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTITATMAGAISAIANFAMFFGGRDENGRPVNPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYAAGIPFQAAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFD
CCCHHHEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA