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The map label for this gene is degS [H]

Identifier: 161526220

GI number: 161526220

Start: 3334604

End: 3335428

Strand: Direct

Name: degS [H]

Synonym: Bmul_3051

Alternate gene names: 161526220

Gene position: 3334604-3335428 (Clockwise)

Preceding gene: 161526219

Following gene: 161526221

Centisome position: 96.7

GC content: 75.03

Gene sequence:

>825_bases
ATGGATACGTCGCTTAATGCGCCCCACGGCGCTCACGCCCCGTTCCCGTCGCGGCTGCCCGCGCCTGGCAGCGCCGCCGC
AACGTCGGCCGATCCCGTTTCGCATCCCGTTTCGCAATCCGATCCGTGCGCACAGCGCATCGCGGTGCTGTCCGCGCAGC
TGCTCGCCGCCGACGAAGCCGCGCGCCGCCATCTGGCCGGCGAGCTGCACGACGGCCTCGGCGCAGAACTCACCGCCGCC
CGATTCGCGCTCGCCAACGCTCAGGCGTGGCTGCCGGCCGACGCGCCGCAAGGTTGCCTGCGCGCGCTCGAGCTCGCACA
GCGCGCGCTCGACGCGGCGACCGACGCGAGCCGCCGCCTGATCGACGCACGCGGCGTGCCGGCGTTCGAGAGCGGCGTCG
TGCCCGCGCTGTCCGCGTGGATCGACGGCTTTGCGGCCCGCACCGGCCTGCGCACGAGCTTCGTCTGCGCGGCCGACGCA
CGCGTGCCGCATCTCGCCGGCGACGCCGCGCTCGCAATCTTCCGCGTCGCGCAGGAAGCGCTGTCGAACGTCGCGAAGCA
CGCGCGCGCCGCGTCGGCCGACGTGCGGATCGACGCCGACGACACGTTCCTGTCGCTGATCGTCACCGACGATGGGACCG
GTTTCGCGCGCAAGCGCCGCGCCGGCTACGGGCTCACCGGCATGCAGGCGCGCTGCGCCGCGTTCGGCGGCCGGCTCGAC
ACGGCGTCCGGCGCGGCCGGGCGCGGCACGCGCGTGACCGCGTACTTCGCGTGGGACGCGCTGCTCGGCGCGCCCGCCGC
GGCCCGTTTCGCATCGCTGTCGTGA

Upstream 100 bases:

>100_bases
TTGGCATGCCGCCGTTTTCCGGCCGCATGCGCGAGCCGGACGGCCGCCGACCCGCGCCGCCGACCGGCGTCTGAACCGCT
TTCTGACAGCAGGGAGAGTC

Downstream 100 bases:

>100_bases
GGTCGCGATGGGCCTGAACATCCTGCTCGTGGACGACCACGCGATCGTCCGGCAAGGGATCTGCCAGCTGCTCGTCGACC
GCGGCATCGCACGCGAGGTC

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDTSLNAPHGAHAPFPSRLPAPGSAAATSADPVSHPVSQSDPCAQRIAVLSAQLLAADEAARRHLAGELHDGLGAELTAA
RFALANAQAWLPADAPQGCLRALELAQRALDAATDASRRLIDARGVPAFESGVVPALSAWIDGFAARTGLRTSFVCAADA
RVPHLAGDAALAIFRVAQEALSNVAKHARAASADVRIDADDTFLSLIVTDDGTGFARKRRAGYGLTGMQARCAAFGGRLD
TASGAAGRGTRVTAYFAWDALLGAPAAARFASLS

Sequences:

>Translated_274_residues
MDTSLNAPHGAHAPFPSRLPAPGSAAATSADPVSHPVSQSDPCAQRIAVLSAQLLAADEAARRHLAGELHDGLGAELTAA
RFALANAQAWLPADAPQGCLRALELAQRALDAATDASRRLIDARGVPAFESGVVPALSAWIDGFAARTGLRTSFVCAADA
RVPHLAGDAALAIFRVAQEALSNVAKHARAASADVRIDADDTFLSLIVTDDGTGFARKRRAGYGLTGMQARCAAFGGRLD
TASGAAGRGTRVTAYFAWDALLGAPAAARFASLS
>Mature_274_residues
MDTSLNAPHGAHAPFPSRLPAPGSAAATSADPVSHPVSQSDPCAQRIAVLSAQLLAADEAARRHLAGELHDGLGAELTAA
RFALANAQAWLPADAPQGCLRALELAQRALDAATDASRRLIDARGVPAFESGVVPALSAWIDGFAARTGLRTSFVCAADA
RVPHLAGDAALAIFRVAQEALSNVAKHARAASADVRIDADDTFLSLIVTDDGTGFARKRRAGYGLTGMQARCAAFGGRLD
TASGAAGRGTRVTAYFAWDALLGAPAAARFASLS

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788812, Length=209, Percent_Identity=29.1866028708134, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 28072; Mature: 28072

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSLNAPHGAHAPFPSRLPAPGSAAATSADPVSHPVSQSDPCAQRIAVLSAQLLAADEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARRHLAGELHDGLGAELTAARFALANAQAWLPADAPQGCLRALELAQRALDAATDASRRL
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDARGVPAFESGVVPALSAWIDGFAARTGLRTSFVCAADARVPHLAGDAALAIFRVAQEA
HHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
LSNVAKHARAASADVRIDADDTFLSLIVTDDGTGFARKRRAGYGLTGMQARCAAFGGRLD
HHHHHHHHHHCCCCEEECCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHCCCCC
TASGAAGRGTRVTAYFAWDALLGAPAAARFASLS
CCCCCCCCCCEEEEEEEHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MDTSLNAPHGAHAPFPSRLPAPGSAAATSADPVSHPVSQSDPCAQRIAVLSAQLLAADEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARRHLAGELHDGLGAELTAARFALANAQAWLPADAPQGCLRALELAQRALDAATDASRRL
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDARGVPAFESGVVPALSAWIDGFAARTGLRTSFVCAADARVPHLAGDAALAIFRVAQEA
HHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
LSNVAKHARAASADVRIDADDTFLSLIVTDDGTGFARKRRAGYGLTGMQARCAAFGGRLD
HHHHHHHHHHCCCCEEECCCCEEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHCCCCC
TASGAAGRGTRVTAYFAWDALLGAPAAARFASLS
CCCCCCCCCCEEEEEEEHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]