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The map label for this gene is engD [H]

Identifier: 161526040

GI number: 161526040

Start: 3135134

End: 3136228

Strand: Direct

Name: engD [H]

Synonym: Bmul_2871

Alternate gene names: 161526040

Gene position: 3135134-3136228 (Clockwise)

Preceding gene: 161526034

Following gene: 161526043

Centisome position: 90.91

GC content: 64.57

Gene sequence:

>1095_bases
ATGAGCCTCAAATGCGGCATCGTCGGCTTGCCCAACGTCGGCAAGTCCACTCTGTTCAATGCGCTGACCAAGGCCGGCAT
CGCCGCCGAGAACTACCCGTTCTGCACGATCGAGCCGAACGTCGGCATCGTCGAAGTGCCCGATGCGCGCCTGAAGGCGC
TCGCCGAAATCGTGAAGCCCGAGCGCATCGTGCCGGCCGTCGTCGAGTTCGTCGACATCGCGGGCCTCGTCGCCGGCGCG
AGCAAGGGCGAAGGCCTCGGCAACCAGTTCCTCGCGAACATTCGCGAAACCGATGCGATCACGCACGTCGTGCGCTGCTT
CGAGGACGACAACGTCGTCCACGTCGCAGGCAAGGTGAGCCCGATCGACGACATCGAGGTGATCAACACCGAACTCGCGC
TCGCCGATCTCGGCACGGTCGAGAAGGCGCTCGCGCGCTATTCGAAGGCCGCGAAGTCCGGCAACGACAAGGAAGCGGCG
AAGCTCGTCGCGGTGCTCGACAAGGTGCGCGCGCATCTGGACCAGGGCAAGGCCGTGCGCGGCCTCGCGCTGTCCGACGA
CGAGCAGGCGCTGCTCAAGCCGTTCTGTCTGATCACGGCGAAGCCGGCGATGTACGTCGCGAACGTGAAGGACGACGGTT
TCGAGAACAACCCGCACCTCGACGCGGTGCGCAAGTACGCGGAAAGCGAGAATTCGCCCGTGGTCGCGGTGTGCGCGGCG
ATCGAAGCGGAAATCGCCGATCTCGACGATGCCGACAAGGAAGCGTTCCTCGCCGACATGGGCATGTCGGAGCCGGGTCT
CGATCGCGTGATCCGCGCCGGCTTCAAGCTGCTCGGGCTGCAGACGTACTTCACCGCGGGCGTGAAGGAAGTGCGCGCGT
GGACGATCCACATCGGCGACACCGCGCCGCAGGCGGCCGGCGTGATCCACACCGACTTCGAGCGCGGCTTCATTCGCGCG
CAGACGATCGCGTTCGACGATTTCATCGCATATAAGGGCGAGCAAGGCGCGAAGGAAGCCGGCAAGATGCGCGCGGAAGG
GAAGGAATATGTCGTGCACGACGGCGATGTGATGAACTTCCTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
TGAACGCCGGCCCGTCGCGCTGCCCAGCGCCGGCCGCCCTCTTTGTCCTGCGCCGCCGCGCCCTGCCCGGCCGCGCCGCT
TCATCCGTTCGAAGGATTCC

Downstream 100 bases:

>100_bases
GCGTCGTTTCGATGCTGCCGTGAGAAAGCCCGCTCGATGCGGGCTTTTTCTTTATGAGCGTGGACGCTGTCACCTTGGAA
GCGTGCGCAGGCTCTCCGGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDARLKALAEIVKPERIVPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDDNVVHVAGKVSPIDDIEVINTELALADLGTVEKALARYSKAAKSGNDKEAA
KLVAVLDKVRAHLDQGKAVRGLALSDDEQALLKPFCLITAKPAMYVANVKDDGFENNPHLDAVRKYAESENSPVVAVCAA
IEAEIADLDDADKEAFLADMGMSEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRA
QTIAFDDFIAYKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV

Sequences:

>Translated_364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDARLKALAEIVKPERIVPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDDNVVHVAGKVSPIDDIEVINTELALADLGTVEKALARYSKAAKSGNDKEAA
KLVAVLDKVRAHLDQGKAVRGLALSDDEQALLKPFCLITAKPAMYVANVKDDGFENNPHLDAVRKYAESENSPVVAVCAA
IEAEIADLDDADKEAFLADMGMSEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRA
QTIAFDDFIAYKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV
>Mature_363_residues
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDARLKALAEIVKPERIVPAVVEFVDIAGLVAGAS
KGEGLGNQFLANIRETDAITHVVRCFEDDNVVHVAGKVSPIDDIEVINTELALADLGTVEKALARYSKAAKSGNDKEAAK
LVAVLDKVRAHLDQGKAVRGLALSDDEQALLKPFCLITAKPAMYVANVKDDGFENNPHLDAVRKYAESENSPVVAVCAAI
EAEIADLDDADKEAFLADMGMSEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRAQ
TIAFDDFIAYKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.8184281842818, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI58761502, Length=225, Percent_Identity=35.5555555555556, Blast_Score=145, Evalue=8e-35,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=70.0549450549451, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=28.3687943262411, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.9836065573771, Blast_Score=290, Evalue=6e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.2953929539295, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.3562005277045, Blast_Score=204, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6321649, Length=166, Percent_Identity=38.5542168674699, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=42.1195652173913, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=42.1195652173913, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=42.1195652173913, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.5705521472393, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24585318, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39011; Mature: 38880

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDARLKALAEIVKP
CCCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
ERIVPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDDNVVHVAGKVS
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDIEVINTELALADLGTVEKALARYSKAAKSGNDKEAAKLVAVLDKVRAHLDQGKAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GLALSDDEQALLKPFCLITAKPAMYVANVKDDGFENNPHLDAVRKYAESENSPVVAVCAA
CEEECCCHHHHHCCHHEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEH
IEAEIADLDDADKEAFLADMGMSEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
TAPQAAGVIHTDFERGFIRAQTIAFDDFIAYKGEQGAKEAGKMRAEGKEYVVHDGDVMNF
CCCCCCCCEEECCCCCEEEEEEEEHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCHHHHH
LFNV
HHCC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDARLKALAEIVKP
CCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
ERIVPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDDNVVHVAGKVS
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDIEVINTELALADLGTVEKALARYSKAAKSGNDKEAAKLVAVLDKVRAHLDQGKAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GLALSDDEQALLKPFCLITAKPAMYVANVKDDGFENNPHLDAVRKYAESENSPVVAVCAA
CEEECCCHHHHHCCHHEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEH
IEAEIADLDDADKEAFLADMGMSEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
TAPQAAGVIHTDFERGFIRAQTIAFDDFIAYKGEQGAKEAGKMRAEGKEYVVHDGDVMNF
CCCCCCCCEEECCCCCEEEEEEEEHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCHHHHH
LFNV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]