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The map label for this gene is ung [H]

Identifier: 161526034

GI number: 161526034

Start: 3129073

End: 3129978

Strand: Direct

Name: ung [H]

Synonym: Bmul_2865

Alternate gene names: 161526034

Gene position: 3129073-3129978 (Clockwise)

Preceding gene: 161526033

Following gene: 161526040

Centisome position: 90.74

GC content: 71.63

Gene sequence:

>906_bases
ATGGCAACCCGCAAGACCTCCCGCACGCCGCTGCAGGCGTCGCTGTTCGACGATCCCGTGCCGGAAACGGCCGAGGCCGA
CCTTCGGCCCGCTGCGCCGGCCGCTCCCGCAGCCGAGCGCCGGCCGGCCGGCAAGATCGCTGCCGGCGCCGCGGCCGCCC
CGCACGCCGCGCACGCCGCGCGCGACATTCCGCACCTCGCCGCGCAATTCGATGCACTGCCCGCCGTATGGCGCGACGTG
CTGAAGCCGTTCATCGACAGCGACGCATACGCGCCGCTGTGCCGCTTCGTCGACGACGAACGCGCGGCCGGCAAGACGAT
CTACCCGACCGACGTGTTCCGCGCACTGCGGCTGACGAGCCCCGACGACGTGAAGGTCGTGATCCTCGGCCAGGACCCTT
ATCACGGCGACGATCGCGGCACGCCGCAGGCGCACGGCCTCGCATTCTCGGTGCCGCCCGCCGTGCGCACGCCGCCGTCG
CTGCGCAACATCTTCAAGGAAATCTCCGCGAACTTCGGCCACGATACGCCGCGCCACGGCTGTCTCGACACGTGGGCGCG
TCAAGGCGTGCTGCTGCTGAACACCGTGCTGACGGTCGAGCGCGGCGCGGCCGCGAGCCACGCGAAGCGCGGCTGGGAGC
AGTGCACCGATACGCTGATCCGCGAGCTCGCGAACCGTCATCGCGGGCTCGTGTTCATGCTGTGGGGCGCGCACGCGCAG
GCGAAGCGCGCGCTGTTCGACGCGAGTGCGCACTGCGTGCTCGAGGCGCCGCATCCGTCGCCGCTGTCCGCGCATCGCGG
CTTTCTCGGCTGCCGCCACTTCGCGCTCGCGAACGACTATCTGGTCGAGCACGGCCGCACGCCGATCGACTGGCGGCTTC
CCGCGGTCGCCGAAACGCTCGCGTAA

Upstream 100 bases:

>100_bases
GCCGCCGAGCTGCAGCAGGCGCTGCCGGGTCTCGCTCCCGAAAACATCAGCAAGGCGCAGCGCGGCTACCGGCTGCGCGC
GCAATAAACCCGCATCACGC

Downstream 100 bases:

>100_bases
CGGCGGCCGCGCCGCGTCCTGCGTCGGCCGGAATGCAAAACGGCCGGAATGCAAAAGCGCCGCGCCCCTGTCGGGACGCG
GCGCTTTTTGTTTGCAGATC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MATRKTSRTPLQASLFDDPVPETAEADLRPAAPAAPAAERRPAGKIAAGAAAAPHAAHAARDIPHLAAQFDALPAVWRDV
LKPFIDSDAYAPLCRFVDDERAAGKTIYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPS
LRNIFKEISANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELANRHRGLVFMLWGAHAQ
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEHGRTPIDWRLPAVAETLA

Sequences:

>Translated_301_residues
MATRKTSRTPLQASLFDDPVPETAEADLRPAAPAAPAAERRPAGKIAAGAAAAPHAAHAARDIPHLAAQFDALPAVWRDV
LKPFIDSDAYAPLCRFVDDERAAGKTIYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPS
LRNIFKEISANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELANRHRGLVFMLWGAHAQ
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEHGRTPIDWRLPAVAETLA
>Mature_300_residues
ATRKTSRTPLQASLFDDPVPETAEADLRPAAPAAPAAERRPAGKIAAGAAAAPHAAHAARDIPHLAAQFDALPAVWRDVL
KPFIDSDAYAPLCRFVDDERAAGKTIYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSL
RNIFKEISANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELANRHRGLVFMLWGAHAQA
KRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEHGRTPIDWRLPAVAETLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=221, Percent_Identity=49.3212669683258, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI6224979, Length=221, Percent_Identity=49.3212669683258, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1788934, Length=228, Percent_Identity=57.0175438596491, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=42.9223744292237, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6323620, Length=251, Percent_Identity=40.2390438247012, Blast_Score=158, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 32633; Mature: 32502

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRKTSRTPLQASLFDDPVPETAEADLRPAAPAAPAAERRPAGKIAAGAAAAPHAAHAA
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHCCCCCCCHHHHHH
RDIPHLAAQFDALPAVWRDVLKPFIDSDAYAPLCRFVDDERAAGKTIYPTDVFRALRLTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC
PDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEISANFGHDTPRHG
CCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
CLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELANRHRGLVFMLWGAHAQ
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHH
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEHGRTPIDWRLPAVAETL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHC
A
C
>Mature Secondary Structure 
ATRKTSRTPLQASLFDDPVPETAEADLRPAAPAAPAAERRPAGKIAAGAAAAPHAAHAA
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHCCCCCCCHHHHHH
RDIPHLAAQFDALPAVWRDVLKPFIDSDAYAPLCRFVDDERAAGKTIYPTDVFRALRLTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC
PDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEISANFGHDTPRHG
CCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
CLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELANRHRGLVFMLWGAHAQ
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHH
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEHGRTPIDWRLPAVAETL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA