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The map label for this gene is obgE [H]

Identifier: 161525969

GI number: 161525969

Start: 3053945

End: 3055054

Strand: Reverse

Name: obgE [H]

Synonym: Bmul_2800

Alternate gene names: 161525969

Gene position: 3055054-3053945 (Counterclockwise)

Preceding gene: 161525970

Following gene: 161525968

Centisome position: 88.59

GC content: 67.12

Gene sequence:

>1110_bases
ATGAAGTTCATTGACGAAGCGCGAATCGAAGTCATTGCCGGCGATGGAGGCGATGGCAGCGCGTCGATGCGCCGCGAAAA
ATTCGTTCCGTTCGGCGGGCCGGACGGCGGCGACGGCGGCCGGGGCGGCAGCGTCTACGCAATCGCCGACCGCAACATCA
ACACGCTGATCGACTACCGATACGCGAAGAAGCATTTGGCGCGCAACGGCGAAAACGGCCGCGGCTCCGATTGCTACGGC
AAGGGCGGCGACGACATCACGCTGCGCATGCCGGTCGGCACGGTGATCACCGACATGGACACCGGCGAGCTGATCGCCGA
TCTGACCGAGCACGACCAGCAGGTGCTGCTCGCGAAAGGCGGCGCCGGCGGCCTCGGCAACCTGCATTTCAAGTCGAGCA
CGAACCGCGCGCCGCGGCAGAAGACCGACGGCAAGCCGGGCGAGCGGCGCATGCTGAAGCTCGAGCTGAAGGTGCTCGCC
GACGTCGGTCTGCTCGGCATGCCGAATGCGGGCAAGTCGACGTTCATCTCCTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGATTACCCGTTCACGACGCTCGCGCCGAATCTCGGCGTCGTGCGCGTCGGCCCGAGCAAGAGCTTCGTGATCGCCGACA
TCCCGGGGCTGATCGAGGGCGCGGCCGAAGGCGCGGGCCTTGGCCATCAGTTCCTGCGGCACTTGCAGCGCACCGGTCTG
CTGCTGCATCTCGTCGACATCGCGCCGTTCGACGAAGGCGTCGATCCGGTCGCCGAAGCGACGGCGATCGTCGGCGAGCT
GCGCAAGTACGACGAGGCGCTCTACGAGAAGCCGCGCTGGCTCGTGCTGAACAAGCTCGACATGGTGCCCGAGGACGAGC
GTGCGGCACGCGTCGCCGATTTTCTCGAGCGCTTCGACTGGCACGGCCCCGTGTTCGAGATTTCCGCGTTGACGGGGCAG
GGCTGCGAAGCGCTGTGCTACGCGATCTACGACTATCTGGCCGAGCATTCGGACGCGCATCGCGCGGCGGAGGCGGAAGA
TCTGGCGGCAGACGTGCGCTTCCGCGATGCGCCGCCGGCCGCCAACGCTGCGCCGGGCGACGACGCCTGA

Upstream 100 bases:

>100_bases
GGCGGTCGTCGCAAAAACCGGCGCACGATTGGCCGAACGGCCGATTGTTCAAGCGCGCCGGCGCGCGGCACAATAGCGGA
AATACTGGGCGGAGTAACGA

Downstream 100 bases:

>100_bases
GCGTACCCGTCACGCGCCGGTCTGCGTCGGTCCGGCGCCGGAATTGAATCGCGCCCGGCCGGGCAGGCATCAGATACAGG
AGACAGCGCACGATGCGTTC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDMDTGELIADLTEHDQQVLLAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDIAPFDEGVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERAARVADFLERFDWHGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDAPPAANAAPGDDA

Sequences:

>Translated_369_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDMDTGELIADLTEHDQQVLLAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDIAPFDEGVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERAARVADFLERFDWHGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDAPPAANAAPGDDA
>Mature_369_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDMDTGELIADLTEHDQQVLLAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHLVDIAPFDEGVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERAARVADFLERFDWHGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDAPPAANAAPGDDA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=38.3928571428571, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI111955139, Length=390, Percent_Identity=34.3589743589744, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI111955063, Length=292, Percent_Identity=32.5342465753425, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=33.6134453781513, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=58.3333333333333, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=339, Percent_Identity=37.7581120943953, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=30.2469135802469, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=179, Percent_Identity=37.4301675977654, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6321773, Length=155, Percent_Identity=30.3225806451613, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=37.0786516853933, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=41.2162162162162, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI20129375, Length=336, Percent_Identity=37.797619047619, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39541; Mature: 39541

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDITLRMPVGTVITDMDTGELIADLTEHDQQVLLAKG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDIAPFDEGVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERAARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FLERFDWHGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDAPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCC
ANAAPGDDA
CCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDITLRMPVGTVITDMDTGELIADLTEHDQQVLLAKG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHEEHHHHHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDIAPFDEGVDPVAEATAIVGELRKYDEALYEKPRWLVLNKLDMVPEDERAARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FLERFDWHGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEAEDLAADVRFRDAPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCC
ANAAPGDDA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA