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The map label for this gene is ruvB [H]

Identifier: 161525865

GI number: 161525865

Start: 2943969

End: 2945036

Strand: Direct

Name: ruvB [H]

Synonym: Bmul_2696

Alternate gene names: 161525865

Gene position: 2943969-2945036 (Clockwise)

Preceding gene: 161525864

Following gene: 161525866

Centisome position: 85.37

GC content: 68.35

Gene sequence:

>1068_bases
ATGATTGAAACCGACAAACTCGCCGCCGAGCGGATCATTGCCGCCACGCCCGCCTCGTCGCACGAGGAGGTGTTCGAACG
CGCGCTGCGGCCGCGCCAGCTCGACGACTACGTCGGCCAGGAAAAGGTGCGCGGCCAGCTCGAAATCTTCATCGAGGCGG
CCAAGCGCCGCCGCGAGCCGCTCGATCACGTGCTGCTGTTCGGGCCGCCGGGCCTCGGCAAGACCACGCTCGCGCACATC
ATCGCGCGTGAGATGGGCGTGAACCTGCGTCAGACCTCGGGCCCCGTGCTCGAGCGCGCGGGCGACCTCGCGGCCTTGCT
GACGAACCTCGAAGCCAACGACGTGCTGTTCATCGACGAGATCCACCGGCTGTCGCCGGTCGTCGAGGAAATCCTGTATC
CGGCGCTCGAGGATTACCAGATCGACATCATGATCGGCGAAGGGCCGGCCGCGCGCAGCGTGAAGCTCGATCTGCAGCCG
TTCACGCTGGTCGGCGCGACCACGCGCGCGGGCATGCTGACCAATCCGCTGCGCGACCGGTTCGGGATCGTCGCGCGCCT
CGAGTTCTACGATGCCGATCAGCTGTCGCGCATCGTGCAGCGCTCGGCGTCGCTGCTGAACGCGCAGATCGATCCGAACG
GCGCGCTCGAGATCGCGAAGCGCTCGCGCGGCACGCCGCGGATCGCGAACCGGCTGCTGCGTCGCGTGCGCGATTACGCG
GAAGTGAAGGCCGACGGCCAGATCACGGCGGCGATCGCCGACGCGGCGCTCGCGATGCTCGATGTCGATCCGGTCGGCTT
CGACCTGATGGACCGCAAGCTGCTCGAAGCGATCCTGCACAAGTTCGACGGCGGCCCGGTCGGCATCGACAACCTCGCTG
CCGCAATCGGCGAAGAGCGCGACACGATCGAGGACGTGCTCGAACCGTACCTGATCCAGCAGGGCTTCCTGCAGCGCACG
CCGCGCGGCCGCGTCGCGACGCTGCTCACGTACCGCCACTTCGGCCTGGCCGCGCCCGACGCCGGCAGTCCCGTGCAAAG
CATCTGGGACACGCCGGACGCGCAGTAA

Upstream 100 bases:

>100_bases
GTAACGGCCCGTCGCATCCAGTGTCGCGCGGCGTCGGCGCGCGCGACAGTCGGCCGTTCGGCCAGGTTGGCCGCGCCACG
CCGCGCGGTACAATGGCCGC

Downstream 100 bases:

>100_bases
CGCACGGCCCGACACCCGGCCCGCCATGACGACACCGCACAGCGCTCCGCCTTCTACCGCCGGCAGCTCGCGGTGGATCG
AACAGATCCGCAAGCGGGTC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIETDKLAAERIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRREPLDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDADQLSRIVQRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGQITAAIADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLAAPDAGSPVQSIWDTPDAQ

Sequences:

>Translated_355_residues
MIETDKLAAERIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRREPLDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDADQLSRIVQRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGQITAAIADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLAAPDAGSPVQSIWDTPDAQ
>Mature_355_residues
MIETDKLAAERIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRREPLDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDADQLSRIVQRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGQITAAIADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGIDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLAAPDAGSPVQSIWDTPDAQ

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=340, Percent_Identity=70.8823529411765, Blast_Score=476, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 39117; Mature: 39117

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDKLAAERIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRREP
CCCCHHHHHHHHHEECCCCCHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCC
LDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDE
CCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDR
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHH
FGIVARLEFYDADQLSRIVQRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDYA
HCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
EVKADGQITAAIADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGIDNLAAAIGEER
HHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCH
DTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLAAPDAGSPVQSIWDTPDAQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MIETDKLAAERIIAATPASSHEEVFERALRPRQLDDYVGQEKVRGQLEIFIEAAKRRREP
CCCCHHHHHHHHHEECCCCCHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCC
LDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDE
CCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDR
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHH
FGIVARLEFYDADQLSRIVQRSASLLNAQIDPNGALEIAKRSRGTPRIANRLLRRVRDYA
HCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
EVKADGQITAAIADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGIDNLAAAIGEER
HHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCH
DTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLAAPDAGSPVQSIWDTPDAQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA