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The map label for this gene is tldD [H]

Identifier: 161525814

GI number: 161525814

Start: 2886500

End: 2887966

Strand: Direct

Name: tldD [H]

Synonym: Bmul_2645

Alternate gene names: 161525814

Gene position: 2886500-2887966 (Clockwise)

Preceding gene: 161525813

Following gene: 161525815

Centisome position: 83.7

GC content: 68.17

Gene sequence:

>1467_bases
ATGAACATCATCGAACCCGGCATCCGCAACCTGGCGCTGGCGAAGGACATCCTGCTGACGCCGTACGGCCTCGACGAGAG
CCTGCTCACGCGCACGATCGCGGACATCTTCACGCACCGCGTCGACTACGCGGATCTGTACTTCCAGGCAACGCGCAGCG
AGGCGTGGAGCCTCGAGGAAGGCATCGTGAAGTCGGGCAGCTTCAGCATCGATCAGGGCGTCGGCGTGCGCGCGGTGGCG
GGCGACCGCACCGCGTTCGCGTATTCGGACGACCTGTCGCCGGAAGCGATCGCGCAGGCCGCCGCGGCGACGAAGGCGAT
CGCGGCCGCGGGCGGCGGCCGCCAGAAGGTGAAGGCGGCGACCTCGCTGAAAGGCATCTCGGGCCGCGACCTCTATCTGC
CGTCCGATCCGCTCGCGTCGCTCGACGCGACGGCCAAGGTGAAGCTGCTCGAACGCGTCGAGCAGATGGCGCGCAGCCGC
GACCCGCGCATCACGCAGGTCATGGCGGGCCTCGCCGGCGAATACGACGTCGTGCTCGTCGCGCGCAGCGACGGCGCGCT
CGCAGCCGACATCCGCCCGCTCGTACGCGTCTCGGTCACGGTCATCGCCGAGCAGAACGGTCGCCGCGAAATCGGCACCG
GCGGCGGCGGCGGCCGCTTCGACTACGGCTACTTCACCGACGACGTGCTGTCGCGCTACGTCGACGACGCGGTGCATGCC
GCGCTCGTGAACCTCGACGCGCGCCCCGCGCCGGCCGGCGCGATGACGGTCGTGCTCGGGCCGGGCTGGCCGGGCGTGCT
GCTGCACGAGGCGATCGGCCACGGTCTCGAGGGCGACTTCAACCGCAAGGGTTCGTCGGCGTTCGCGGGCCGCATCGGCG
AGCAAGTCGCCGCGAAGGGCGTGACGGTCGTCGACGACGGCACGCTGCCGAACCGTCGCGGCTCGCTCAACATCGACGAC
GAAGGCAACCCGACGCAGTGCACGACGCTGATCGAGGACGGGATCCTGAAGGGCTACATCCAGGACACGCTGAACGCGCG
CCTGATGAAGATGCCGGTCACGGGCAACGCGCGCCGCGAATCGTATGCGGCGCTGCCGATGCCGCGCATGACCAATACCT
ACATGCTCAACGGCGACAAGGATCCGCAGGAAATCATCGCGTCGGTGAAGAACGGTCTCTACGCGGTGAACTTCGGCGGC
GGCCAGGTCGACATCACGAACGGCAAGTTCGTGTTCTCGGCGTCCGAGGCGTACATGATCGAGAACGGCAAGATCACGTA
TCCGGTCAAGGGCGCGACGCTGATCGGCAGCGGCCCCGAATCGCTGAAGTACGTGAGCATGATCGGCAACGACATGTCGC
TCGACACGGGCGTCGGCGTATGCGGCAAGGAAGGCCAGAGCGTGCCGGTCGGCGTCGGCCAGCCGACCCTGCGCATCGAC
AAGATGACGGTCGGCGGTACGGCATAA

Upstream 100 bases:

>100_bases
CGCGTACTGACCTGAGCGGCCGGTCCGCTTGAAACGCCGCGCGGCCCACCCATCTGCGCGATACGCATCCGACAACTTTT
TGAGAGCACCCGATACCCGC

Downstream 100 bases:

>100_bases
CCGCATCGCCGCGCAGACAATCCGCGTATTTTTGACCGAACGCGCGGATTGTCCGCATTTTTGACGCACCCCGGTTGCCA
GCGGCACGGCGACCGGGTAT

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKVKAATSLKGISGRDLYLPSDPLASLDATAKVKLLERVEQMARSR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGTGGGGGRFDYGYFTDDVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA

Sequences:

>Translated_488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKVKAATSLKGISGRDLYLPSDPLASLDATAKVKLLERVEQMARSR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGTGGGGGRFDYGYFTDDVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA
>Mature_488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKVKAATSLKGISGRDLYLPSDPLASLDATAKVKLLERVEQMARSR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGTGGGGGRFDYGYFTDDVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=485, Percent_Identity=58.1443298969072, Blast_Score=543, Evalue=1e-155,
Organism=Escherichia coli, GI1790682, Length=444, Percent_Identity=24.3243243243243, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51449; Mature: 51449

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKVKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSLKGISGRDLYLPSDPLASLDATAKVKLLERVEQMARSRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGTGGGGGRFDYGYFTDDVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTA
EEECCCCC
>Mature Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKVKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSLKGISGRDLYLPSDPLASLDATAKVKLLERVEQMARSRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGTGGGGGRFDYGYFTDDVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKITYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTA
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]