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The map label for this gene is nrdR [H]

Identifier: 161525749

GI number: 161525749

Start: 2804701

End: 2805180

Strand: Reverse

Name: nrdR [H]

Synonym: Bmul_2580

Alternate gene names: 161525749

Gene position: 2805180-2804701 (Counterclockwise)

Preceding gene: 161525750

Following gene: 161525748

Centisome position: 81.35

GC content: 64.17

Gene sequence:

>480_bases
ATGCGCTGCCCGTTCTGCCGGCACGAAGACACGCAAGTCGTTGACTCCCGCGTGTCCGAGGATGGCGCCGCGATTCGCCG
GCGCCGTCGCTGCTCGGCTTGCGACAAGCGCTTCACGACGTACGAGCGGGTCGAGTTGAACCTGCCGGCCGTCGTGAAGA
AGGACGGCAGCCGCACCGAATTCGACCGTCGCAAGATCGTCGCCAGCATGCAACTCGCGCTGCGCAAGCGGCCCGTTGCT
GCGGATGCGATCGACGCGGCGGTCGCTCGTATCGAATATCAACTGCTCGCGACCGGCGAGCGTGAAGTGCGTAGCGAGAA
GCTCGGCGAACTCGTGATGAACGAGTTGCGCGGCCTCGATACGATTGCCTATGTCCGCTTCGCATCGGTGTATCGCCGGT
TCGAGGACGTGTCCGAATTTGCCGACGTGATCGAAGAGTTCCGTCGCGCCTCTCCCGCCAAGCCTCCGCGTAAGCGCTGA

Upstream 100 bases:

>100_bases
CGACGTGCTCGAGAACCCGGAAGACGCAGCGACGATCGAGCGCGTGCGCGCACAGGTCGCCGAGCTGACCAAGCGCTTCC
CGGTCTACCGCTGATCGACG

Downstream 100 bases:

>100_bases
CGCGCTGCGTCCGTTCATCGCCTGCTCCTGTCGTTCAGTTCGCGCCGATTGTGTCGGTTGCATGCGCTCGCCGTCAGTCG
GCCGTTCGGCATATGGTGCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKPPRKR

Sequences:

>Translated_159_residues
MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKPPRKR
>Mature_159_residues
MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKPPRKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=51.3888888888889, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18381; Mature: 18381

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCH
TIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKPPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCH
TIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKPPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA