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The map label for this gene is pcaR [H]

Identifier: 161525738

GI number: 161525738

Start: 2797240

End: 2798031

Strand: Reverse

Name: pcaR [H]

Synonym: Bmul_2569

Alternate gene names: 161525738

Gene position: 2798031-2797240 (Counterclockwise)

Preceding gene: 161525740

Following gene: 161525737

Centisome position: 81.14

GC content: 69.95

Gene sequence:

>792_bases
ATGACACTTTCAACCATCGACGACACCACCATCGACGAGCGCAAGTTCGTCGTCGCGCTCGCGCGCGGGCTCGACTTGCT
GCGCGCGTTCCGGCCCGGCGAGACGATGCTCGGCAATCGCGACTTCGCGCAGCGCACCGGCTTGCCGAAGGCGACCGTGA
ACCGGCTCGCGTACACGCTGACGGTGCTCGGCTATCTGCGCTACGACGAGACGCTAGGCAAGTATGCGCTCGACGCCGGC
GTGCTGTCGCTCGGCTATGCGCTGCTGTCGGGCGCCGGCACGATCGATCTCGCGCGGCCGCACATGCAGGCGCTCGCGCG
CGAGATCGGTGCGGCCGTGTCGCTCGGTTGCCGGGACGGGCTCGACATGATCTACCTGGAGACGATCCGCAGCGAGACGG
CGCTGACGCTCGGGCTCGCGCCCGGCTCGCGGCTGTCGATGCTGACGAGCTCGATGGGTCGTGCCTATCTGGCCGTGCAG
CCCGACGACGTGCGGCGCGCGCTGTACGCGGAACTGCACAAGGCGGCCGGCGGCGCGGACGATGCGGATGCGCTGGTCGC
CGCGGCGCAGGCGGCGGTCGCCGAATTTCCGGAAAGCGGCTGCTGCTATTCGTTCCGCGCGTGGCACGCCGACGTCAATG
CGGCAGCCGTGCCGTTTCGCGAACCGCGCGAAGGGCGCTGGCTGATTCTCAGTTGCAGCGGGCCGGCGTCGTCGATGGGC
GAGGAGGTGTTCCGCACGCAGGTCGGGCCGAAGCTGAAGGCGCTCGCGCAGCGGCTCGGGCAGACGGTCTGA

Upstream 100 bases:

>100_bases
CCAATGAAAAGTTGCAGCGCTCATCGTGTCATCTCCTGACTTGACTGGAGTTCCGCTGTGCGGAACAATGTTTTGCAAAT
TGATCCCAGTGTAGCATCGG

Downstream 100 bases:

>100_bases
CGAACGGTCGCGCGAGACGGCAGCGGCGCCGTTCGGCGGCAGATCGCCGAAATCGGCAAACGCGTCCGGCCCGCGGTTGC
GGACCGAGCGGACCGCGCTC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAQRTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGAGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PDDVRRALYAELHKAAGGADDADALVAAAQAAVAEFPESGCCYSFRAWHADVNAAAVPFREPREGRWLILSCSGPASSMG
EEVFRTQVGPKLKALAQRLGQTV

Sequences:

>Translated_263_residues
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAQRTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGAGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PDDVRRALYAELHKAAGGADDADALVAAAQAAVAEFPESGCCYSFRAWHADVNAAAVPFREPREGRWLILSCSGPASSMG
EEVFRTQVGPKLKALAQRLGQTV
>Mature_262_residues
TLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAQRTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAGV
LSLGYALLSGAGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQP
DDVRRALYAELHKAAGGADDADALVAAAQAAVAEFPESGCCYSFRAWHADVNAAAVPFREPREGRWLILSCSGPASSMGE
EVFRTQVGPKLKALAQRLGQTV

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=165, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28158; Mature: 28026

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAQRTGLPKATVNRLAYTL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGAGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPDDVRRALYAELHKAAGGAD
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCC
DADALVAAAQAAVAEFPESGCCYSFRAWHADVNAAAVPFREPREGRWLILSCSGPASSMG
CHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCEECCCCCCCCCCEEEEECCCCHHHHH
EEVFRTQVGPKLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAQRTGLPKATVNRLAYTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGAGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPDDVRRALYAELHKAAGGAD
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCC
DADALVAAAQAAVAEFPESGCCYSFRAWHADVNAAAVPFREPREGRWLILSCSGPASSMG
CHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCEECCCCCCCCCCEEEEECCCCHHHHH
EEVFRTQVGPKLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]