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The map label for this gene is ahpC [C]

Identifier: 161525740

GI number: 161525740

Start: 2799414

End: 2800052

Strand: Reverse

Name: ahpC [C]

Synonym: Bmul_2571

Alternate gene names: 161525740

Gene position: 2800052-2799414 (Counterclockwise)

Preceding gene: 161525744

Following gene: 161525738

Centisome position: 81.2

GC content: 59.94

Gene sequence:

>639_bases
ATGAGTCTGCGTCTTGGCGACATCGCACCGGATTTCGAGCAGGAATCGAGCCTGGGCCCGATCAAGTTTCACGAGTGGCT
CGGCGATAGCTGGGGTGTCCTGTTCTCCCATCCGGCCGACTACACGCCGGTGTGCACGACGGAACTCGGGCTGACCGCGA
AGCTGAAGGACGAATTCGCGAAACGCAACGTGAAGGTGATCGCGCTGTCGGTCGACGGCGTCGAATCGCACAAAGGCTGG
ATCAACGACATCAACGAAACGCAGTCGACGGTCGTCGGTTTCCCGATCATCGCCGATGCGGATCGCAAGGTCTCGCAGCT
GTACGACATGATCCATCCGAACGCGAACGAGACGCTGACGGTGCGCTCGCTGTTCGTGATCGATCCGAACAAGAAGGTGC
GGCTGATCATCACGTATCCGGCCAGCACCGGGCGCAATTTCGACGAAGTGCTGCGCGTAATCGACTCGCTGCAACTGACC
GACAACTACAAGGTCGCGACGCCCGGCAACTGGAAGGACGGCGACGACGTCGTGATCGTGCCGTCGCTGCAGGATCCGGA
AGAACTGAAGAAGCGTTTCCCGAAGGGCTTCAATGCGGTGCGTCCGTATCTGCGTCTGACGCCGCAGCCGAACAAGTAA

Upstream 100 bases:

>100_bases
TAATAATCGTTCGCATGGCCCATTGCTTCCCGTAAGCTGATGGACTGTCCCGCGCCGACCGCGCGCGGTTTCAACTTGCA
TCGTTCGAGGAGGGAACACC

Downstream 100 bases:

>100_bases
AGCCATCGTCGCGCGCCGTATCGGCGGCATGCGCAAAACGGCCCGCCCGGCAGTCATGCCGGGCGGGCCGTGTCGTTTCC
GCCCATCGCGTGTAATACGG

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQESSLGPIKFHEWLGDSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKVIALSVDGVESHKGW
INDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DNYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQESSLGPIKFHEWLGDSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKVIALSVDGVESHKGW
INDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLT
DNYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQESSLGPIKFHEWLGDSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKVIALSVDGVESHKGWI
NDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTD
NYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=53.6036036036036, Blast_Score=231, Evalue=3e-61,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=32.1052631578947, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI5453549, Length=164, Percent_Identity=32.3170731707317, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI32483377, Length=164, Percent_Identity=31.0975609756098, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI5802974, Length=164, Percent_Identity=31.0975609756098, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=32.4675324675325, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=191, Percent_Identity=43.979057591623, Blast_Score=163, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=30.7291666666667, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=30.7291666666667, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17554494, Length=159, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=56.1320754716981, Blast_Score=232, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=30.5732484076433, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=50.2283105022831, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=53.3980582524272, Blast_Score=210, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=53.3980582524272, Blast_Score=209, Evalue=9e-55,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=53.3980582524272, Blast_Score=209, Evalue=9e-55,
Organism=Drosophila melanogaster, GI17738015, Length=200, Percent_Identity=32.5, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17157991, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641739, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=28.4090909090909, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23805; Mature: 23674

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQESSLGPIKFHEWLGDSWGVLFSHPADYTPVCTTELGLTAKLKDEFA
CCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRNVKVIALSVDGVESHKGWINDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCHHEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTDNYKVATPGNWKDGDDVVIV
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEECCCCCCCCCCCEEEE
PSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCCHHHCHHEEECCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQESSLGPIKFHEWLGDSWGVLFSHPADYTPVCTTELGLTAKLKDEFA
CCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRNVKVIALSVDGVESHKGWINDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCHHEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLIITYPASTGRNFDEVLRVIDSLQLTDNYKVATPGNWKDGDDVVIV
EEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEECCCCCCCCCCCEEEE
PSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCCHHHCHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]