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The map label for this gene is apaH [H]

Identifier: 161525687

GI number: 161525687

Start: 2737829

End: 2738665

Strand: Direct

Name: apaH [H]

Synonym: Bmul_2518

Alternate gene names: 161525687

Gene position: 2737829-2738665 (Clockwise)

Preceding gene: 161525682

Following gene: 161525696

Centisome position: 79.39

GC content: 68.22

Gene sequence:

>837_bases
ATGCTCGCTCCCATCGCCATCGGCGACATCCAAGGCTGTCATTCAGCTTTCGATTCGCTGCTGAAAAAACTCTCCGCCCC
CGCCGATACGCCGCTCTGGATCGCCGGCGACATCGTGAACCGCGGCCCCGGCTCGCTCGCCGCGCTGCGCGCGCTGGTCG
ACCTCGGCCCGCGCGTCACGGCTGTCCTGGGCAACCACGACCTGCACCTGCTCGCCGTCTCGGCCGGCATCCGCACCGAA
CGCCGCGGCGACACGATCGGCGAGATCCTCGACGCGCCCGACGCCGACGCACTGCTCGACTGGGTCCGCCACCGCCCGTT
CGCGCATTTCCAAGACGGCAAACTGCTCGTTCACGCGGGCGTGCTGCCGCAATGGGACGTGACGCTCGCCCTCGAGCTCG
CGGACGAGCTTCAGCAGGCACTACGCGCCCCCGACTGGCGCGAGACGCTGCAAAAGCTGTACGGCAACGAGCCGAACCAG
TGGAATCCGAACCTAAAAAAGCGCGACCGGATGCGCGTCGCGTTCAACGCTTTCACGCGCCTGCGGTTCTGCACCCCGGA
CGGGGCTATGGAATTCAAGGCGAACGGCGGCCCCGAGAGCGCGCCGCCCGGCCATCTGCCGTGGTTCGACGTGCCGGGCC
GCCGCACCGAAGACGTGACGGTCGTGTTCGGCCATTGGGCCGCGCTCGGCCTGATGCTGCGCGACAACGTGGTGGCGCTC
GATTCGGGATGCGTATGGGGAAATCAGCTGTCGGCCGTGCGCCTGACGGCCGATCCGGCACAGCGCACGGTCACGCAGGT
GCAATGCGAAGCATGCCGCACACCAGGCGGCGAATGA

Upstream 100 bases:

>100_bases
TCGCATCCGCAAGCGCCCGCGCCTGATATGGGACCGCCGTCGCGCGCTGCTCGTTTGTACGATTTTTTTCTCTTTACCCC
GATCTAGCAAATCCGACCTC

Downstream 100 bases:

>100_bases
CCGCAATGTAACGGCCGCAGCCCGCGCCAACGGGCCGCGGCACGATCAGCCTTCGCGCCCCGGCACCGGCTCTTCGGCGG
CACCGTCGCGGGCCGCGTCC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MLAPIAIGDIQGCHSAFDSLLKKLSAPADTPLWIAGDIVNRGPGSLAALRALVDLGPRVTAVLGNHDLHLLAVSAGIRTE
RRGDTIGEILDAPDADALLDWVRHRPFAHFQDGKLLVHAGVLPQWDVTLALELADELQQALRAPDWRETLQKLYGNEPNQ
WNPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPESAPPGHLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNVVAL
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRTPGGE

Sequences:

>Translated_278_residues
MLAPIAIGDIQGCHSAFDSLLKKLSAPADTPLWIAGDIVNRGPGSLAALRALVDLGPRVTAVLGNHDLHLLAVSAGIRTE
RRGDTIGEILDAPDADALLDWVRHRPFAHFQDGKLLVHAGVLPQWDVTLALELADELQQALRAPDWRETLQKLYGNEPNQ
WNPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPESAPPGHLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNVVAL
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRTPGGE
>Mature_278_residues
MLAPIAIGDIQGCHSAFDSLLKKLSAPADTPLWIAGDIVNRGPGSLAALRALVDLGPRVTAVLGNHDLHLLAVSAGIRTE
RRGDTIGEILDAPDADALLDWVRHRPFAHFQDGKLLVHAGVLPQWDVTLALELADELQQALRAPDWRETLQKLYGNEPNQ
WNPNLKKRDRMRVAFNAFTRLRFCTPDGAMEFKANGGPESAPPGHLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNVVAL
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRTPGGE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=257, Percent_Identity=43.9688715953307, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30334; Mature: 30334

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPIAIGDIQGCHSAFDSLLKKLSAPADTPLWIAGDIVNRGPGSLAALRALVDLGPRVT
CCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEE
AVLGNHDLHLLAVSAGIRTERRGDTIGEILDAPDADALLDWVRHRPFAHFQDGKLLVHAG
EEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEECCCCEEEEEC
VLPQWDVTLALELADELQQALRAPDWRETLQKLYGNEPNQWNPNLKKRDRMRVAFNAFTR
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHE
LRFCTPDGAMEFKANGGPESAPPGHLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNVVAL
EEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEEE
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRTPGGE
ECCCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLAPIAIGDIQGCHSAFDSLLKKLSAPADTPLWIAGDIVNRGPGSLAALRALVDLGPRVT
CCCCEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEE
AVLGNHDLHLLAVSAGIRTERRGDTIGEILDAPDADALLDWVRHRPFAHFQDGKLLVHAG
EEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEECCCCEEEEEC
VLPQWDVTLALELADELQQALRAPDWRETLQKLYGNEPNQWNPNLKKRDRMRVAFNAFTR
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHE
LRFCTPDGAMEFKANGGPESAPPGHLPWFDVPGRRTEDVTVVFGHWAALGLMLRDNVVAL
EEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEEE
DSGCVWGNQLSAVRLTADPAQRTVTQVQCEACRTPGGE
ECCCEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA